Results 21 to 30 of about 1,551 (116)

ANALGESIC ACTIVITY OF SOME NEW SYNTHETIC DIBENZO-α-PYRONES DERIVATIVES

INTERNATIONAL JOURNAL OF RESEARCH IN AYURVEDA & PHARMACY, 2014
Following standard Hurtley reaction, by using 2 - Bromobenzoic acid, resorcinol and NaOH in the presence of CuSO 4 solution as a catalyst, a clay coloured solid of dibenzo - α - pyrone was prepared. This resulting solid of DBαP was then reacted with various amines respectively, formaldehyde and ethanol and refluxed for 1.5 h as per Mannich reaction ...
Shalini Sawhney, Y Kumar, Ankita Sahai, B Shrivastava   +3 more
openaire   +1 more source

Coumarins, Xanthones and Related Compounds

Molecules, 2016
It has long been known that coumarins (γ-pyrones) and xanthones (α-pyrones) together form a large class of naturally occurring compounds exhibiting a wide range of biological activities.[...]
Pascal Richomme
doaj   +1 more source

Pd/C-Catalyzed Intramolecular C–H Arylation for the Synthesis of Phenanthridinones and Dibenzo-α-pyrones

SynOpen, 2017
Pd/C was found to be an efficient and convenient metal catalyst for intramolecular C–H arylation reactions in the synthesis of phenanthridinones and dibenzo-α-pyrones. A variety of phenanthridinones and dibenzo-α-pyrones were synthesized under the highly
Lingyu Zhao, Guodong Shen, Tongxin Zhang, Zhen Wang, Yuhua Liang   +4 more
doaj   +1 more source

Molecular Docking of Cryptoconcatones to α-Tubulin and Related Pironetin Analogues

Plants, 2023
Cryptoconcatones A-L represent a series of 12 dihydropyrone derivatives isolated from the evergreen tree Cryptocarya concinna Hance, which is well distributed in southeast Asia.
Gérard Vergoten, Christian Bailly
doaj   +1 more source

Nocapyrones: α- and γ-Pyrones from a Marine-Derived Nocardiopsis sp.

Marine Drugs, 2014
One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2–4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment.
Youngju Kim, Hiromu Ogura, Kazuaki Akasaka, Tsutomu Oikawa, Nobuyasu Matsuura, Chiaki Imada, Hisato Yasuda, Yasuhiro Igarashi   +7 more
doaj   +1 more source

Sulfur-containing benzofurans and α-pyrones from the mangrove-derived fungus Talaromyces sp. WHUF0341

Frontiers in Marine Science, 2022
Two new sulfur-containing benzofurans, talarobenzofurans A and B (1 and 2), one new benzofuran talarobenzofuran C (3) and two new α-pyrones talaropyrones A and B (5 and 6), along with five known compounds eurothiocin A (4), nodulisporipyrone A (7 ...
Ruohan Zhang, Ruohan Zhang, Jinxin Zhang, Jinxin Zhang, Ruiyun Huo, Ruiyun Huo, Yaxin Xue, Kui Hong, Ling Liu, Ling Liu   +9 more
doaj   +1 more source

Assignment of Absolute Configurations of Two Promising Anti-Helicobacter pylori Agents from the Marine Sponge-Derived Fungus Aspergillus niger L14

Molecules, 2021
A chemical investigation into endozoic fungus Aspergillus niger L14 derived from the marine sponge of Reniera japonica collected off Xinghai Bay (China) resulted in the isolation of two dimeric naphtho-γ-pyrones, fonsecinone A (1) and isoaurasperone A (2)
Jia Liu, Ronglu Yu, Jia Jia, Wen Gu, Huawei Zhang   +4 more
doaj   +1 more source

Bioactive α-Pyrone Derivatives from the Endophytic Fungus Diaporthe sp. CB10100 as Inducible Nitric Oxide Synthase Inhibitors

Frontiers in Chemistry, 2021
Inducible nitric oxide synthase (iNOS) produces NO from l-arginine and plays critical roles in inflammation and immune activation. Selective and potent iNOS inhibitors may be potentially used in many indications, such as rheumatoid arthritis, pain, and ...
Hong Pu, Hong Pu, Hong Pu, Jianxin Liu, Yeji Wang, Yuhui Peng, Wanying Zheng, Yang Tang, Boping Hui, Chunmei Nie, Xueshuang Huang, Yanwen Duan, Yanwen Duan, Yanwen Duan, Yong Huang, Yong Huang   +15 more
doaj   +1 more source

Combinatory Exposure to Urolithin A, Alternariol, and Deoxynivalenol Affects Colon Cancer Metabolism and Epithelial Barrier Integrity in vitro

Frontiers in Nutrition, 2022
The human gastrointestinal tract is an important site of nutrient absorption and a crucial barrier against xenobiotics. It regularly faces “chemical cocktails” composed of food constituents, their human and microbial metabolites, and foodborne ...
Julia Groestlinger, Carina Seidl, Elisabeth Varga, Giorgia Del Favero, Giorgia Del Favero, Doris Marko   +5 more
doaj   +1 more source

Integration of Antimicrobials and Delivery Systems: Synergistic Antibiofilm Activity with Biodegradable Nanoemulsions Incorporating Pseudopyronine Analogs

Antibiotics, 2023
Multi-drug-resistant (MDR) bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), pose a significant challenge in healthcare settings.
Jungmi Park, Neel Mahida, Gabrielle Ho, Elizabeth Pena, Jessa Marie V. Makabenta, Stanley Aneke, Mingdi Jiang, Leah M. Bouthillette, Stephanie E. Holz, Muhammad Aamir Hassan, Amanda L. Wolfe, Vincent M. Rotello   +11 more
doaj   +1 more source