Results 21 to 30 of about 2,390 (158)
Plants, 2023 This study aimed at the evaluation of the antioxidant and cognitive-enhancing effect of methanol–aqueous extract from Helichrysum italicum ssp. italicum aerial parts.
Reneta Gevrenova +6 more
doaj +1 more source
CRISPR-Cas9-Based Discovery of the Verrucosidin Biosynthesis Gene Cluster in Penicillium polonicum
Frontiers in Microbiology, 2021 Penicillium polonicum, commonly found on food matrices, is a mycotoxigenic species able to produce a neurotoxin called verrucosidin. This methylated α-pyrone polyketide inhibits oxidative phosphorylation in mitochondria and thereby causes neurological ...
Silvia Valente +11 more
doaj +1 more source
Divergent rhodium-catalyzed electrochemical vinylic C–H annulation of acrylamides with alkynes
Nature Communications, 2021 α-Pyridones and α-pyrones are ubiquitous structural motifs found in natural products and components of biologically active small molecules. Here, the authors report an oxidant-free Rh-catalyzed electrochemical divergent vinylic C–H annulation of ...
Yi-Kang Xing +6 more
doaj +1 more source
Bioactive Monoterpenes and Polyketides from the Ascidian-Derived Fungus Diaporthe sp. SYSU-MS4722
Marine Drugs, 2022 There has been a tremendous increase in the rate of new terpenoids from marine-derived fungi being discovered, while new monoterpenes were rarely isolated from marine-derived fungi in the past two decades. Three new monoterpenes, diaporterpenes A–C (1–3),
Guifa Zhai +5 more
doaj +1 more source
Marine Drugs, 2022 With the increasingly serious antimicrobial resistance, discovering novel antibiotics has grown impendency. The Antarctic abundant microbial resources, especially fungi, can produce unique bioactive compounds for adapting to the hostile environment.
Ting Shi +6 more
doaj +1 more source
Two new -Methoxy--Pyrones From the Mangrove Sediment-Derived SCSIO NS126
Natural Product Communications, 2021 Two new α -methoxy- γ -pyrone analogs, 2-methoxy-3-methyl-5,6-diethyl- γ -pyrone ( 2 ) and 2-methoxy-3,5-dimethyl-6-propyl- γ -pyrone ( 3 ), together with 2-methoxy-3,5-dimethyl-6-ethyl- γ -pyrone ( 1 ), firstly isolated from natural sources, were ...
Kunlong Li +6 more
doaj +1 more source
ANALGESIC ACTIVITY OF SOME NEW SYNTHETIC DIBENZO-α-PYRONES DERIVATIVES
INTERNATIONAL JOURNAL OF RESEARCH IN AYURVEDA & PHARMACY, 2014 Following standard Hurtley reaction, by using 2 - Bromobenzoic acid, resorcinol and NaOH in the presence of CuSO 4 solution as a catalyst, a clay coloured solid of dibenzo - α - pyrone was prepared. This resulting solid of DBαP was then reacted with various amines respectively, formaldehyde and ethanol and refluxed for 1.5 h as per Mannich reaction ...
Shalini Sawhney +3 more
openaire +1 more source
Coumarins, Xanthones and Related Compounds
Molecules, 2016 It has long been known that coumarins (γ-pyrones) and xanthones (α-pyrones) together form a large class of naturally occurring compounds exhibiting a wide range of biological activities.[...]
Pascal Richomme
doaj +1 more source
Molecular Docking of Cryptoconcatones to α-Tubulin and Related Pironetin Analogues
Plants, 2023 Cryptoconcatones A-L represent a series of 12 dihydropyrone derivatives isolated from the evergreen tree Cryptocarya concinna Hance, which is well distributed in southeast Asia.
Gérard Vergoten, Christian Bailly
doaj +1 more source
Nocapyrones: α- and γ-Pyrones from a Marine-Derived Nocardiopsis sp.
Marine Drugs, 2014 One new α-pyrone (nocapyrone R (1)), and three known γ-pyrones (nocapyrones B, H and L (2–4)) were isolated from the culture extract of a Nocardiopsis strain collected from marine sediment.
Youngju Kim +7 more
doaj +1 more source