Results 121 to 130 of about 287,721 (287)

Gamma-aminobutyric acid for delaying type 1 diabetes mellitus: an update [PDF]

Annals of Pediatric Endocrinology & Metabolism
The current gold-standard management of hyperglycemia in individuals with type 1 diabetes mellitus (T1DM) is insulin therapy. However, this therapy is associated with a high incidence of complications, and delaying the onset of this disease produces a ...
Jane Carissa Sutedja, Bryan Gervais de Liyis, Made Ratna Saraswati   +2 more
doaj   +1 more source

Chrysanthemum morifolium extract protects HT22 cells from oxidative stress and enhances sleep via GABAergic modulation: contribution of luteolin-7-glucoside. [PDF]

J Sci Food Agric
Abstract BACKGROUND Chrysanthemum morifolium has long been utilized in traditional medicine for its antioxidant and sedative properties, yet its potential in sleep regulation and neuroprotection against oxidative stress remains underexplored. This study investigates the antioxidant and sleep‐enhancing effects of C.
Kim H, Chung SH, Kim S, Ko S, Jung JC, Lee HJ, Lee H.   +6 more
europepmc   +2 more sources

Inhibition of activity of GABA transporter GAT1 by δ-opioid receptor [PDF]

, 2012
Analgesia is a well-documented effect of acupuncture. A critical role in pain sensation plays the nervous system, including the GABAergic system and opioid receptor (OR) activation.
Fucke, Thomas, Gu, Quanbao, Pei, Gang, Pu, Lu, Ren, Shuanglai, Schwarz, Wolfgang, Xia, Peng, Xu, Nanjie   +7 more
core   +2 more sources

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source

Structural determination of the human taurine transporter TauT reveals the mechanism of substrate and inhibitor recognition

Cell Reports
Summary: Taurine, a sulfur-containing amino acid, is vital for human health because of its antioxidant, anti-inflammatory, and osmoregulatory properties. Its homeostasis is maintained by the Na+/Cl−-dependent taurine transporter (TauT).
Yishuo Lu, Dian Ding, Hongyi Chen, Peijun Jiang, Juan Luo, Hui Shan, Guangxi Wang, Jianyuan Luo, Yuxin Yin   +8 more
doaj   +1 more source

Real‐time quality and safety monitoring of fruit juice using paper‐based platform

Food Biomacromolecules, EarlyView.
Schematic illustration of a paper‐based biosensor for rapid detection of fruit juice spoilage. Abstract Food spoilage and safety concerns still remain critically challenging within the fruit juice industry, especially as conventional detection methods, though precise, are often too time‐consuming, costly, and reliant on centralized laboratories.
Priti Das, Srushti Bhoite, Noopur Patil, Shubhro Chakrabartty, Debjani Dutta   +4 more
wiley   +1 more source

Neurotransmitter-gated ion channels at fast chemical synapses: from structure to pathology [PDF]

, 2005
Fil: Bouzat, Cecilia Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Bahía Blanca. Instituto de Investigaciones Bioquímicas de Bahía Blanca. Universidad Nacional del Sur.
Bouzat, Cecilia Beatriz
core  

Percolation in living neural networks [PDF]

, 2006
We study living neural networks by measuring the neurons' response to a global electrical stimulation. Neural connectivity is lowered by reducing the synaptic strength, chemically blocking neurotransmitter receptors.
D. Stauffer, E. Maeda, Elisha Moses, Ilan Breskin, J. G. White, Jordi Soriano, M. Papa, Tsvi Tlusty, Y. Jimbo   +8 more
core   +2 more sources

Microbial influences on immune modulation and colorectal cancer progression through combined transcriptomic and microbiomic analysis

iMetaOmics, EarlyView.
Schematic representation of the distinct tumor microenvironment characteristics in CA1 and CA2 subtypes. CA1 illustrates an immune‐active tumor microenvironment characterized by elevated infiltration of immune cells, particularly CD8 + T cells and macrophages, and enhanced IFN‐γ signaling.
Shuting Xia, Likun Wang, Yangzhuo Xu, Jiaqi Zhang, Zeyang Zhou, Libing Sun, Heng Li, Chungen Xing, Jialu Mao, Yina Liu, Fulin Yang, Ling Zhong, Jiancheng Xu, Xiaodong Yang, Zhemin Zhou   +14 more
wiley   +1 more source

Pharmacological characterisation of murine α4β1δ GABAA receptors expressed in Xenopus oocytes [PDF]

, 2015
BACKGROUND: GABAA receptor subunit composition has a profound effect on the receptor's physiological and pharmacological properties. The receptor β subunit is widely recognised for its importance in receptor assembly, trafficking and post-translational ...
Smart, TG, Villumsen, IS, Wellendorph, P
core   +1 more source