Results 151 to 160 of about 59,395 (233)

Ivermectin Toxicity in Humans and Animals: Clinical Spectrum, Mechanisms, and Management

open access: yesJournal of Applied Toxicology, Volume 46, Issue 6, Page 1856-1870, June 2026.
ABSTRACT Ivermectin is a widely used macrocyclic lactone with established efficacy against a broad range of parasitic infections in humans and animals and a long‐standing reputation for clinical safety. However, increasing evidence indicates that ivermectin can produce clinically relevant toxicity under specific conditions, particularly involving the ...
Serkan Yilmaz   +3 more
wiley   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao   +4 more
wiley   +1 more source

Formulation and Pharmacological Evaluation of a Medicine‐Food Homology Herb‐Based Formula for Sleep Enhancement

open access: yesPhytochemicals in Food and Medicine, Volume 1, Issue 2, June 2026.
This outlines the progress for developing a sleep‐modulating herbal formula (SMF). It begins with the identification of effective compounds and quality control, then uses network pharmacology and molecular docking to explain the mechanisms behind the observation found on the behavioural and neurobiological results in animal study.
Jasmine U. Ting   +7 more
wiley   +1 more source

Changes in DOM Quality Determine Prokaryotic Activities and Extracellular Release in the NW Mediterranean Sea: An Experimental Approach

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 3, June 2026.
Changes in DOM composition influence prokaryotic species growth in the Mediterranean Sea, shaping their metabolic responses and organic matter processing. In our study, higher DOP consumption and alkaline phosphatase activity led to the accumulation of recalcitrant DOM, highlighting how microbial community shifts drive distinct pathways in carbon ...
Eva Ortega‐Retuerta   +9 more
wiley   +1 more source

Quantifying microbiota impact on plant traits for the guidance of breeding programs

open access: yes
New Phytologist, EarlyView.
Manuel Blouin   +5 more
wiley   +1 more source

SemaGBA: A System Dynamics Model of the Semaglutide‐Responsive Gut‐Brain Axis A Model of How the Brain and Semaglutide Regulate Appetite and Weight

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue 6, Page 5184-5194, June 2026.
ABSTRACT Aims Semaglutide is a GLP‐1 receptor agonist for the treatment of type 2 diabetes and obesity. Its clinical effects are well established, but the underlying mechanisms remain unclear. This study aims to use computational modelling to generate hypotheses about semaglutide's long‐term metabolic (body weight, net energy intake, blood glucose ...
Vivan C. W. Kennis, Natal A. W. van Riel
wiley   +1 more source

Asymptomatic Versus Symptomatic Alzheimer's Disease Neuropathology: A Systematic Review of Differences Reported in Post‐Mortem Studies

open access: yesNeuropathology and Applied Neurobiology, Volume 52, Issue 3, June 2026.
Graphical summary of post‐mortem brain tissue findings that differ between symptomatic and asymptomatic AD. Current evidence suggests reduced accumulation of Aβ and p‐tau oligomers, particularly at synapses, preserved neuronal and synaptic integrity and metabolic activity and a dynamic profile of glial and immune responses in ASYMAD.
Thiago Guilherme Rêgo Barros   +6 more
wiley   +1 more source

Microbial Controls on Dissolved Organic Nitrogen Cycling During Long‐Term Degradation Experiments

open access: yesGeophysical Research Letters, Volume 53, Issue 10, 28 May 2026.
Abstract Dissolved organic nitrogen (DON) is critical for marine microbial growth by providing carbon and nitrogen. Although DON is rapidly cycled, some compounds within this pool can persist for long‐periods of time. To better understand how DON is cycled by marine microorganisms, we conducted 548‐day incubations using surface‐derived dissolved ...
Richard LaBrie   +5 more
wiley   +1 more source

Priming of plant innate immunity by β-aminobutyric acid improved barley resistance to grain aphid (Sitobion avenae). [PDF]

open access: yesBMC Plant Biol
Alamri A   +5 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy