Results 91 to 100 of about 4,070 (167)

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

Nature Communications
Tetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic approaches for stereoselective synthesis of tetrahydro-β-carboline skeletons have
Xiaochen Tian, Tengfei Xuan, Jingkun Gao, Xinyu Zhang, Tao Liu, Fengbiao Luo, Ruochen Pang, Pengcheng Shao, Yun-Fang Yang, Yang Wang   +9 more
doaj   +1 more source

Total Synthesis and Biological Activity of Marine Alkaloid Eudistomins Y1–Y7 and Their Analogues

Marine Drugs, 2013
Eudistomin Y class compounds are a series of β-carbolines which was originally isolated from a marine turnicate or ascidian near the South Korea Sea.
Tao Jiang, Shengbiao Wan, Moulay A. Alaoui-Jamali, Sumei Ren, Puyong Zhang, Krikor Bijian, Huijuan Jin   +6 more
doaj   +1 more source

Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L. [PDF]

, 2005
To study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated from a methanolic extract from the seeds of P. harmala L.
Berrougui, Hicham, Ettaib, Abdelkader, Herrera González, María Dolores, López Lázaro, Miguel, Mamouchi, Mohamed, Martín Cordero, Carmen   +5 more
core  

Synthesis of 1,4‐Disubstituted and 1‐Substituted β‐Carbolines via 3‐Substituted 2‐Acylindoles [PDF]

β-Carbolines represent a large class of bioactive natural products, whereby most of these alkaloids bear residues at C1, and occasionally at C3, and only limited examples of 1,4-disubstituted β-carbolines are known.
Bracher, Franz, Jourjine, Ilya A. P., Thees, Katharina, Untergehrer, Martin   +3 more
core   +1 more source

Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol

Brazilian Journal of Pharmaceutical Sciences, 2018
Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as ...
Júlia Movilla Pires, Fúlvio Rieli Mendes, Ana Paula Salum Pires, Maurício Yonamine, José Luiz Gomes do Amaral, Elisaldo Araújo Carlini   +5 more
doaj   +1 more source

Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles. [PDF]

Int J Mol Sci, 2023
Aksenov NA, Arutiunov NA, Aksenov AV, Kirilov NK, Aksenova IV, Aksenov DA, Aleksandrova EV, Rubin M, Kornienko A.   +8 more
europepmc   +1 more source

Discovery of novel antitumor nitric oxide-donating b-elemene hybrids through inhibiting the PI3K/Akt pathway [PDF]

, 2017
A series of novel furoxan-based NO-donating b-elemene hybrids were designed and synthesized to improve the anticancer efficacy of natural b-elemene.
Chen, Jichao, Lin, Aijun, Wang, Tianyu, Wu, Liang, Xie, Weijia, Xu, Jinyi, Xu, Shengtao, Yao, Hequan, Zhang, Pengfei, Zhu, Zheying   +9 more
core   +2 more sources

Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala

Molecules, 2010
In a continuing effort to develop novel β-carbolines endowed with better insecticidal activity, a simple high-yielding method for the synthesis of harmine compounds starting from L-tryptophan has been developed and a series of 1,3-substituted β-carboline
Guohua Zhong, Meiying Hu, Qunfang Weng, Yaomou Zhang, Yong Zeng   +4 more
doaj   +1 more source

The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization [PDF]

, 2016
Ayahuasca is an Amazonian psychoactive brew of two main components. Its active agents are β-carboline and tryptamine derivatives. As a sacrament, ayahuasca is still a central element of many healing ceremonies in the Amazon Basin and its ritual ...
Bokor, Petra, Frecska, Ede, Winkelman, Michael   +2 more
core   +2 more sources

Ayahuasca: Uses, Phytochemical and Biological Activities

Natural Products and Bioprospecting, 2019
Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it ...
Edgar Antonio Estrella-Parra, Julio Cesar Almanza-Pérez, Francisco Javier Alarcón-Aguilar   +2 more
doaj   +1 more source