Results 91 to 100 of about 936,414 (160)

Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala

Molecules, 2010
In a continuing effort to develop novel β-carbolines endowed with better insecticidal activity, a simple high-yielding method for the synthesis of harmine compounds starting from L-tryptophan has been developed and a series of 1,3-substituted β-carboline
Guohua Zhong, Meiying Hu, Qunfang Weng, Yaomou Zhang, Yong Zeng   +4 more
doaj   +1 more source

Enantioselective Catalytic Methods for the Elaboration of Chiral Tetrahydro-β-carbolines and Related Scaffolds

, 2017
Tetrahydro-β-carbolines are important synthetic intermediates in the total synthesis of natural products and of compounds exhibiting strong bioactivities.
Nicolas Glinsky-Olivier, Xavier Guinchard   +1 more
core   +1 more source

β-Carbolines that accumulate in human tissues may serve a protective role against oxidative stress

, 2000
β-Carbolines are tricyclic nitrogen heterocycles formed in plants and animals as Maillard reaction products between amino acids and reducing sugars or aldehydes. They are being detected increasingly in human tissues, and their physiological roles need to
Pari, Koteppa, Balasubramanian, Dorairajan, Sivakama Sundari, C., Chandani, Sushil, C.Sivakama Sundari, Koteppa Pari, Sushil Chandani, Dorairajan Balasubramanian   +7 more
core   +1 more source

Oxidation of Tetrahydro-β-carbolines by Persulfate

, 2019
The development of persulfate-mediated oxidation of tetrahydro-β-carbolines is reported. This mild reaction facilitates the formation of a variety of 2-formyl N-substituted tryptamines and the related derivatives as key intermediates in moderate to ...
Haijun Chen (580445), Jing Luo (146659), Yu Gao (69071), Fu Ye (7036157), Jing Luo, Fu Ye, Haijun Chen, Yu Gao   +7 more
core   +1 more source

Highly diastereoselective crystallization-induced asymmetric transformation of 1,3-disubstituted-tetrahydro-β-carbolines in water

, 2017
A green and highly stereoselective method for the synthesis of cis or trans-1,3-disubstituted-tetrahydro-β-carbolines has been developed using water as the solvent.
Xiao-Xin Shi, Zhong-Shou Huang, Hui-Ya Qu, Tian-Zhuo Meng, Yi Zhang, Qi-Qi Fan   +5 more
core   +1 more source

β-carboline alkaloids from Stellaria dichotoma as anti-fibrotic therapeutics against chronic kidney disease

Industrial Crops and Products
β-Carboline alkaloids possess significant industrial value and considerable potential for drug development. In pursuit of potential therapeutic agents for chronic kidney disease (CKD), twenty-one β-carboline alkaloids (1–21), including seven new β ...
Bixuan Cao, Zengguang Zhang, Ye Kang, Hang Lv, Mimi Zhang, Ping Yi, Li Han, Zhongyuan Liu, Xueshi Huang   +8 more
doaj   +1 more source

Electrochemical oxidative rearrangement of tetrahydro-β-carbolines in a zero-gap flow cell. [PDF]

Chem Sci, 2022
Zheng Y, Cheung YT, Liang L, Qiu H, Zhang L, Tsang A, Chen Q, Tong R.   +7 more
europepmc   +1 more source

“Pictet-Spengler-like” Synthesis of Tetrahydro-β-carbolines under Hydrolytic Conditions. Direct Use of Azalactones as Phenylacetaldehyde Equivalents

, 2016
“Pictet-Spengler-like” Synthesis of Tetrahydro-β-carbolines under Hydrolytic Conditions.
James J. Droste (3018369), Gwyn L. Murdoch (3037149), Deborah A. Evrard (2356759), James E. Audia (1398949), Jeffrey S. Nissen (3018375)   +4 more
core   +1 more source

Deep eutectic solvent mediated synthesis of β-carbolines and related natural products via Pictet–Spengler reaction and aerobic oxidation

Tetrahedron Green Chem
An eco-friendly, one-pot synthesis of β-carboline derivatives using deep eutectic solvent is reported. This protocol utilizes commercially available aldehydes and tryptamine, involving Pictet–Spengler cyclization followed by aerobic oxidation.
Bhuvana Narasimman
doaj   +1 more source

Synthesis, Molecular Docking and Antiplasmodial Activities of New Tetrahydro-β-Carbolines. [PDF]

Int J Mol Sci, 2021
Jaromin A, Gryzło B, Jamrozik M, Parapini S, Basilico N, Cegła M, Taramelli D, Zagórska A.   +7 more
europepmc   +1 more source