Results 81 to 90 of about 936,414 (160)

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

Nature Communications
Tetrahydro-β-carboline skeletons are prominent and ubiquitous in an extraordinary range of indole alkaloid natural products and pharmaceutical compounds. Powerful synthetic approaches for stereoselective synthesis of tetrahydro-β-carboline skeletons have
Xiaochen Tian, Tengfei Xuan, Jingkun Gao, Xinyu Zhang, Tao Liu, Fengbiao Luo, Ruochen Pang, Pengcheng Shao, Yun-Fang Yang, Yang Wang   +9 more
doaj   +1 more source

Sc(OTf)₃‑Catalyzed C2-Selective Cyanation/Defluorination Cascade of Perfluoroalkylated 3‑Indolylmethanols and Application to the Synthesis of 3‑Fluoro(perfluoroalkyl)-β-carbolines

An unprecedented Sc­(OTf)3-catalyzed C2-selective cyanation/defluorination cascade of perfluoroalkylated 3-indolylmethanols with TMSCN is described, which provides a novel and practical strategy for the synthesis of structurally diverse 3-(2-cyano ...
Weidong Rao (1598017), Dandan Shang (11458496), Jichao Chen (108786), Qing Bao (1852243), Li Feng (77923), Jingjing Sang (11458493), Rui Hu (505795)   +6 more
core   +1 more source

Développement de nouvelles méthodologies pour la synthèse de spirotétrahydro-β-carbolines

, 2014
The aim of this work was to optimize a new way of synthesis of spirotetrahydro-β-carbolines. A three-steps strategy from the 3-(2-nitrovinyl)indole was elaborated with the following linear sequence : Michael addition, reduction of the nitro function into
Baron, Marc
core   +3 more sources

Formation of Tetrahydro-β-Carbolines in Thermally Processed Foods and Their Detection Methods [PDF]

Shipin Kexue
Tetrahydro-β-carbolines (THβCs) are a class of alkaloids widely existing in foods, and the formation pathways of THβCs in the human body include endogenous and exogenous ones. The endogenous pathway is related to the metabolism of tryptophan in the human
CAO Jiamin, LI Xuechen, XU Jiahao, YANG Yong, HUI Teng
doaj   +1 more source

Inhibition of Monoamine Oxidase from Bovine Retina by β-Carbolines

, 1994
The behaviour of some β-carboline derivatives as inhibitors of monoamine oxidase has been studied in bovine retina. Inhibition was found not to show any significant time dependence.
M Unzeta, M D Balsa, J M Lizcano, A. Fernández De Arribam   +3 more
core   +1 more source

Calorimetric, Thermogravimetric, and Theoretical Study of Norharmane, Harmane, and Harmine: Insights into the Energetics of β-Carbolines

Thermo
The thermochemical properties of Norharmane, Harmane, and Harmine were investigated using DSC, combustion calorimetry, thermogravimetry, and G3B3 computational methods.
Ana Ivette Delgado-Moreno, Raúl Ricardo Quiñonez-López, María de Jesús Palacios-Sánchez, Oscar Guillermo Zúñiga-González, Francisco Javier Moscoso-Sánchez, Eulogio Orozco-Guareño, Jesús Baudelio Campos-García   +6 more
doaj   +1 more source

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

Beilstein Journal of Organic Chemistry, 2011
The carboline ring system is an important pharmacophore found in a number of biologically important targets. Development of synthetic routes for the preparation of these compounds is important in order to prepare a range of analogues containing the ...
Jessica Baiget, Sabin Llona-Minguez, Stuart Lang, Simon P. MacKay, Colin J. Suckling, Oliver B. Sutcliffe   +5 more
doaj   +1 more source

Total Synthesis and Biological Activity of Marine Alkaloid Eudistomins Y1–Y7 and Their Analogues

Marine Drugs, 2013
Eudistomin Y class compounds are a series of β-carbolines which was originally isolated from a marine turnicate or ascidian near the South Korea Sea.
Tao Jiang, Shengbiao Wan, Moulay A. Alaoui-Jamali, Sumei Ren, Puyong Zhang, Krikor Bijian, Huijuan Jin   +6 more
doaj   +1 more source

Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles. [PDF]

Int J Mol Sci, 2023
Aksenov NA, Arutiunov NA, Aksenov AV, Kirilov NK, Aksenova IV, Aksenov DA, Aleksandrova EV, Rubin M, Kornienko A.   +8 more
europepmc   +1 more source

Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol

Brazilian Journal of Pharmaceutical Sciences, 2018
Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as ...
Júlia Movilla Pires, Fúlvio Rieli Mendes, Ana Paula Salum Pires, Maurício Yonamine, José Luiz Gomes do Amaral, Elisaldo Araújo Carlini   +5 more
doaj   +1 more source