Results 61 to 70 of about 1,867 (125)

A Structure–Activity Relationship Study of Trypargine and Opacaline β-Carbolines

Marine Drugs
The marine environment represents a rich source of novel antimicrobial compounds. This study investigated the isolation and synthesis of antimicrobial agents from the New Zealand ascidian Pseudodistoma opacum to identify natural products and derivatives ...
Dan Chen, Florent Rouvier, Jean Michel Brunel, Brent R. Copp, Melissa M. Cadelis   +4 more
doaj   +1 more source

Calorimetric, Thermogravimetric, and Theoretical Study of Norharmane, Harmane, and Harmine: Insights into the Energetics of β-Carbolines

Thermo
The thermochemical properties of Norharmane, Harmane, and Harmine were investigated using DSC, combustion calorimetry, thermogravimetry, and G3B3 computational methods.
Ana Ivette Delgado-Moreno, Raúl Ricardo Quiñonez-López, María de Jesús Palacios-Sánchez, Oscar Guillermo Zúñiga-González, Francisco Javier Moscoso-Sánchez, Eulogio Orozco-Guareño, Jesús Baudelio Campos-García   +6 more
doaj   +1 more source

Manganese dioxide mediated one-pot synthesis of methyl 9H-pyrido[3,4-b]indole-1-carboxylate: Concise synthesis of alangiobussinine

Beilstein Journal of Organic Chemistry, 2011
The carboline ring system is an important pharmacophore found in a number of biologically important targets. Development of synthetic routes for the preparation of these compounds is important in order to prepare a range of analogues containing the ...
Jessica Baiget, Sabin Llona-Minguez, Stuart Lang, Simon P. MacKay, Colin J. Suckling, Oliver B. Sutcliffe   +5 more
doaj   +1 more source

Formation of Tetrahydro-β-Carbolines in Thermally Processed Foods and Their Detection Methods [PDF]

Shipin Kexue
Tetrahydro-β-carbolines (THβCs) are a class of alkaloids widely existing in foods, and the formation pathways of THβCs in the human body include endogenous and exogenous ones. The endogenous pathway is related to the metabolism of tryptophan in the human
CAO Jiamin, LI Xuechen, XU Jiahao, YANG Yong, HUI Teng
doaj   +1 more source

Total Synthesis and Biological Activity of Marine Alkaloid Eudistomins Y1–Y7 and Their Analogues

Marine Drugs, 2013
Eudistomin Y class compounds are a series of β-carbolines which was originally isolated from a marine turnicate or ascidian near the South Korea Sea.
Tao Jiang, Shengbiao Wan, Moulay A. Alaoui-Jamali, Sumei Ren, Puyong Zhang, Krikor Bijian, Huijuan Jin   +6 more
doaj   +1 more source

Synthesis of β-Carbolines with Electrocyclic Cyclization of 3-Nitrovinylindoles. [PDF]

Int J Mol Sci, 2023
Aksenov NA, Arutiunov NA, Aksenov AV, Kirilov NK, Aksenova IV, Aksenov DA, Aleksandrova EV, Rubin M, Kornienko A.   +8 more
europepmc   +1 more source

Pre-clinical interaction of ayahuasca, a brew used in spiritual movements, with morphine and propofol

Brazilian Journal of Pharmaceutical Sciences, 2018
Ayahuasca is a beverage with psychoactive properties used in religious and ceremonial rituals by some religious groups. The main active components of ayahuasca are dimethyltryptamine and the harmala alkaloids with β-carboline structure acting as ...
Júlia Movilla Pires, Fúlvio Rieli Mendes, Ana Paula Salum Pires, Maurício Yonamine, José Luiz Gomes do Amaral, Elisaldo Araújo Carlini   +5 more
doaj   +1 more source

Cytotoxic and Insecticidal Activities of Derivatives of Harmine, a Natural Insecticidal Component Isolated from Peganum harmala

Molecules, 2010
In a continuing effort to develop novel β-carbolines endowed with better insecticidal activity, a simple high-yielding method for the synthesis of harmine compounds starting from L-tryptophan has been developed and a series of 1,3-substituted β-carboline
Guohua Zhong, Meiying Hu, Qunfang Weng, Yaomou Zhang, Yong Zeng   +4 more
doaj   +1 more source

Ayahuasca: Uses, Phytochemical and Biological Activities

Natural Products and Bioprospecting, 2019
Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it ...
Edgar Antonio Estrella-Parra, Julio Cesar Almanza-Pérez, Francisco Javier Alarcón-Aguilar   +2 more
doaj   +1 more source

β-carboline alkaloids from Stellaria dichotoma as anti-fibrotic therapeutics against chronic kidney disease

Industrial Crops and Products
β-Carboline alkaloids possess significant industrial value and considerable potential for drug development. In pursuit of potential therapeutic agents for chronic kidney disease (CKD), twenty-one β-carboline alkaloids (1–21), including seven new β ...
Bixuan Cao, Zengguang Zhang, Ye Kang, Hang Lv, Mimi Zhang, Ping Yi, Li Han, Zhongyuan Liu, Xueshi Huang   +8 more
doaj   +1 more source