Results 61 to 70 of about 947,788 (251)

Ultrasound-Assisted Transglutaminase Catalysis of the Cross-Linking and Microstructure of αs-Casein, β-Casein and κ-Casein

, 2021
The effects of ultrasonic treatment (UT)-assisted transglutaminase (TGase) catalysis on the physicochemical properties of individual αs-casein (αs-CN), β-casein (β-CN), and κ-casein (κ-CN) were investigated.
Chun-Chi Chen, Ken-Lin Chang, Jung-Feng Hsieh, Wen-Tai Li, Hsien-Wei Tseng, Liang-Yu Chen, Bang-Yuan Chen, Chao-Jung Chen   +7 more
core   +1 more source

Macrophage RSAD2 Couples mtDNA Synthesis With a Self‐Amplifying Inflammatory Circuit to Orchestrate Tissue Repair

Advanced Science, EarlyView.
Macrophage RSAD2 dually regulates CMPK2—the rate‐limiting enzyme for mitochondrial DNA synthesis—by suppressing its ubiquitination and promoting its phosphorylation via Csnk2a2 recruitment. This amplifies mtDNA production, which simultaneously activates a cGAS‐STING‐IRF3‐RSAD2 feedforward loop and the NLRP3 inflammasome, driving a self‐sustaining ...
Haomiao Yuan, Shukui Du, Chunfei Li, Xinjie Li, Shuyang Mu, Anran Qu, Hengxu Yan, Chongchong Xu, Jinnong Yang, Jingkai Sun, Yijun Wang, Jiayang Xiao, Fuyuan Zhang, Linlin Wang, Tiegang Li, Rui Zhao, Dawei Guan   +16 more
wiley   +1 more source

A1 β-casein and A2 β-casein: effects on the gastrointestinal motility, digestion, and absorption

Journal of Functional Foods
This study compared A1 and A2 β-casein using a constipated mouse model and ex vivo intestinal sac assays. A2 β-casein significantly improved constipation-related outcomes—enhancing body weight recovery, shortening the first black stool time, increasing ...
Shihang Li, Shijun Sun, Wenzhuang Shen, Meiling Sun, Pengyu Xiang, Xiaoyu Mao, Xuxiang Lu, Hongtao Xu, Yujun Jiang, Xinyan Yang   +9 more
doaj   +1 more source

Developing Metal–Polyphenol Network‐Based Single‐Protein Particle Encapsulation System for Sustained Release of Whey Protein to Mitigate Sarcopenia

Advanced Science, EarlyView.
Sarcopenia has emerged as a major health challenge in the aging population. Developing a sustained‐release system for whey protein may enhance its effectiveness in mitigating sarcopenia. Herein, a novel “single‐protein particle encapsulation” (SPPE) system is developed to protect whey protein and control its release.
Yafei Zhang, Yuning Zhang, Yongjian Ai, Yao Lu, Heng Quan, Zhen Zhang, Yuqi Wang, Yujia Luo, Xiaoxu Zhang, Yingying Lin, Sijia Song, Huiyuan Guo   +11 more
wiley   +1 more source

Casein kinase 2 controls synapse organization and stability [PDF]

, 2013
Synapse remodeling is a local and dynamic process, requiring constant modifications of the neuronal network. Post-translational modifications, such as reversible phosphorylation by kinases and phosphatases, play a crucial role in synapse development and ...
Bulat, Victoria
core   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

EW induces β-casein biosynthesis.

, 2013
(A) and (B): representative western blot showing the levels of the protein β-casein in MCF-7 and MDA-MB-231 cells respectively, after 7 and 11 days of treatment with EW.
Gabriella Dobrowolny (174836), Simona Dinicola (465421), Maria Grazia Masiello (503403), Angela Catizone (132381), Sara Proietti (503404), Giulia Ricci (212589), Alessandra Cucina (465423), Mariano Bizzarri (465425), Fabrizio D’Anselmi (465418), Alessandro Palombo (465424), Alessia Pasqualato (465422)   +10 more
core   +1 more source

Beyond Charge: Field‐Effect Transistors in Multimodal Biosensing Platforms for Biomolecular Interaction Studies

Advanced Electronic Materials, EarlyView.
This review summarizes the developments in field‐effect transistor (FET)‐based dual‐mode sensor platforms and what can be learned from them. It identifies charge as a crucial factor in biomolecular interactions at interfaces, outlines the challenges of hybrid systems, and highlights their benefits.
Roger Hasler, Ciril Reiner‐Rozman, Christoph Kleber, Jakub Dostalek, Wolfgang Knoll   +4 more
wiley   +1 more source

A study of genetic polymorphisms of milk β-lactoglobulin, α S1 -casein, β-casein, and κ-casein in five dairy breeds [PDF]

, 1972
Gene frequencies of the milk β-lactoglobulin, α S1 -casein, β-casein, and κ-casein loci have been estimated from 1663 cows of five dairy breeds. Departure from Hardy-Weinberg equilibrium was found only in the κ-casein system in Jerseys.
Gaunt, Stanley N., Stanley N. Gaunt, Li, Francis H. F., Francis H. F. Li   +3 more
core   +1 more source

Amyloid fibril formation by αS1- and β-casein implies that fibril formation is a general property of casein proteins

, 2022
Caseins are a diverse family of intrinsically disordered proteins present in the milks of all mammals. A property common to two cow paralogues, αS2- and κ-casein, is their propensity in vitro to form amyloid fibrils, the highly ordered protein ...
Carver, John A., Bahraminejad, Elmira, Paliwal, Devashi, Holt, Carl, Thorn, David C., Sunde, Margaret   +5 more
core   +1 more source