Results 261 to 270 of about 1,680,534 (386)

Supplementary Figure S4 from β-Catenin Contributes to Lung Tumor Development Induced by EGFR Mutations

, 2023
Sohei Nakayama, Natasha Sng, Julián Carretero, Robert S. Welner, Yasuhiko Hayashi, Mihoko Yamamoto, Alistair J. Tan, Norihiro Yamaguchi, Hiroyuki Yasuda, Danan Li, Kenzo Soejima, Ross A. Soo, Daniel B. Costa, Kwok‐Kin Wong, Susumu Kobayashi   +14 more
openalex   +1 more source

Supplementary Table 2 from Illegitimate WNT Pathway Activation by β-Catenin Mutation or Autocrine Stimulation in T-Cell Malignancies

, 2023
Richard W.J. Groen, Monique E.C.M. Oud, Esther J.M. Schilder-Tol, Marije B. Overdijk, Derk ten Berge, Roel Nusse, Marcel Spaargaren, Steven T. Pals   +7 more
openalex   +1 more source

Gut Bacterium Lysinibacillus Sphaericus Exacerbates Aspirin‐induced Intestinal Injury by Production of Carboxylesterase EstB

Advanced Science, EarlyView.
Schematic overview illustrating the detrimental role of gut microbiota in aspirin‐induced intestinal injury. L. sphaericus and its secreted carboxylesterase EstB are identified as key drivers that catalyze aspirin hydrolysis into salicylic acid, thereby exacerbating intestinal injury. Inhibition of EstB by the dietary compound flavanomarein effectively
Zeyu Zhao, Qing Li, Xiaowu Bai, Ertao Zhai, Weigang Dai, Yan Qian, Tianhao Zhang, Zhixin Huang, Ziyu Huang, Fangang Meng, Jianhui Chen, Tao Zuo, Shirong Cai, Risheng Zhao   +13 more
wiley   +1 more source

PRC1 promotes immunosuppressive macrophages in sepsis via β-catenin/STAT3 signaling. [PDF]

Cell Mol Life Sci
Zuo Y, Zou S, Wang Z, Liu Y, Xie X, Shen B, Luo G, Lu X, Li N, Jiang W.   +9 more
europepmc   +1 more source

Downregulation of β-catenin blocks fibrosis via Wnt2 signaling in human keloid fibroblasts [PDF]

, 2017
Cai Yu-mei, Shize Zhu, Weiqun Yang, Mingmeng Pan, Chaoyang Wang, Wenyi Wu   +5 more
openalex   +1 more source

Senescent Synovial Intimal Fibroblasts Aggravate Osteoarthritis by Regulating Macrophage Polarization and Chondrocyte Phenotype Through ANGPTL4‐α5β1 Axis

Advanced Science, EarlyView.
Senescent synovial intimal fibroblasts (SIF) are identified as key drivers of osteoarthritis. They promote M1 macrophage polarization and cartilage degeneration via the ANGPTL4–α5β1 axis, regulated by transcription factors EGR1 and ATF3. Pharmacological inhibition of this pathway alleviates disease, revealing SIF senescence as a promising therapeutic ...
Muhai Deng, Yunsheng Jiang, Zhiyu Chen, Kaiquan Chen, Na Cao, Yang Huang, Zhengxue Quan, Cheng Chen   +7 more
wiley   +1 more source

MRPS16 Regulates NFATC2 Through the Wnt/β-Catenin Pathway to Promote Glioma Proliferation. [PDF]

J Cell Mol Med
Li X, Yu S, Wang M, Gong Z, Cheng Q, Wang X, Jiang X.   +6 more
europepmc   +1 more source

Figure S6 from Multilevel Regulation of β-Catenin Activity by SETD2 Suppresses the Transition from Polycystic Kidney Disease to Clear Cell Renal Cell Carcinoma

, 2023
Hanyu Rao, Xiaoxue Li, Min Liu, Jing Liu, Wenxin Feng, Huayuan Tang, Jin Xu, Wei‐Qiang Gao, Li Li   +8 more
openalex   +1 more source

Inferring Gene Regulatory Networks From Single‐Cell RNA Sequencing Data by Dual‐Role Graph Contrastive Learning

Advanced Science, EarlyView.
RegGAIN is a novel and powerful deep learning framework for inferring gene regulatory networks (GRNs) from single‐cell RNA sequencing data. By integrating self‐supervised contrastive learning with dual‐role gene representations, it consistently outperforms existing methods in both accuracy and robustness.
Qiyuan Guan, Jiating Yu, Jieyi Pan, Fan Yuan, Jiadong Ji, Rusong Zhao, Zhi‐Ping Liu, Bingqiang Liu, Ling‐Yun Wu, Duanchen Sun   +9 more
wiley   +1 more source

MUC13 is a crucial player in YAP1-β-catenin survival complex mediated cancer metastasis. [PDF]

Front Med (Lausanne)
Malik S, Sikander M, Yallapu MM, Chauhan SC.   +3 more
europepmc   +1 more source