Evaluation of Metals in a Defined Medium for Pichia pastoris Expressing Recombinant β-Galactosidase
Culture growth and recombinant protein yield of the Pichia pastoris GS115 methanol utilization positive system were studied in response to the types and levels of metals present in the growth medium and the supplemental salts typically used for these fermentations.
Plantz, Bradley A.+3 more
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Cancer cell membrane‐based nanoparticles (CCM‐NPs) and cancer cell‐derived small extracellular vesicles (CsEVs) are emerging as promising drug delivery systems for targeted cancer treatment. Advances in nanotechnology have paved the way for innovative drug delivery systems that enhance the effectiveness of cancer treatment.
Wei Zhang+4 more
wiley +1 more source
The effect of the electric field on lag-phase, ethanol and β-galactosidase production of a recombinant S. cerevisiae growing on lactose [PDF]
The production of ethanol and β-galactosidase from cheese whey and other sub-products from industries can be a good way of minimizing environmental problems and producing valuable products from low-cost raw materials. A recombinant S.
Castro, Inês+2 more
core
Boolean Models of Bistable Biological Systems
This paper presents an algorithm for approximating certain types of dynamical systems given by a system of ordinary delay differential equations by a Boolean network model.
A. Novick+16 more
core +1 more source
Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. [PDF]
Glioblastoma is associated with a poor overall survival despite new treatment advances. Antiangiogenic strategies targeting VEGF based on tyrosine kinase inhibitors (TKIs) are currently undergoing extensive research for the treatment of glioma.
Amantini, C+7 more
core +1 more source
Axitinib induces DNA damage response leading to senescence, mitotic catastrophe, and increased NK cell recognition in human renal carcinoma cells. [PDF]
Tyrosine kinase inhibitors (TKIs) including axitinib have been introduced in the treatment of renal cell carcinoma (RCC) because of their anti-angiogenic properties.
Amantini, C+6 more
core +1 more source
DLC2 modulates angiogenic responses in vascular endothelial cells by regulating cell attachment and migration. [PDF]
Deleted in liver cancer 1 (DLC1) is a RhoGTPase activation protein-containing tumor suppressor that associates with various types of cancer. Although DLC2 shares a similar domain structure with that of DLC1, the function of DLC2 is not well characterized.
Chen, N-T+5 more
core +3 more sources
Mechanistic Investigation of β-Galactosidase-Activated MR Contrast Agents
We report a mechanistic investigation of an isomeric series of beta-galactosidase-activated magnetic resonance contrast agents. Our strategy focuses on the synthesis of macrocyclic caged-complexes that coordinatively saturate a chelated lanthanide. Enzyme cleavage of the complex results in an open coordination site available for water that creates a ...
Urbanczyk Pearson, Lauren M.+7 more
openaire +5 more sources
IMOBILIZAÇÃO DA ENZIMA Î’-GALACTOSIDASE DE Aspergillus oryzae EM RESINAS DE TROCA IÔNICA
Este trabalho apresenta como objetivo estudar o processo de imobilização da enzima β-galactosidase de Aspergillus oryzae por adsorção, utilizando como suporte resinas de troca iônica Duolite A-568, Duolite S-761, Dowex Marathon A, Dowex Marathon C e Amberlite 252 Na.
Santana, Larissa Nayhara Soares+2 more
openaire +1 more source
Wheat as a kind of diet material can be used for broiler production. However, due to non‐starch polysaccharides (NSP) in wheat, wheat may lead to lower growth performance and worth health. This experiment used solid‐state fermentation pro‐enzymes (SFP enzymes) to reverse the negative effect of wheat.
Jiaheng Li+8 more
wiley +1 more source