Results 61 to 70 of about 877,496 (234)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Dietary β-1,3-Glucan Promotes Growth Performance and Enhances Non-Specific Immunity by Modulating Pattern Recognition Receptors in Juvenile Oriental River Prawn (Macrobrachium nipponense)

Fishes
As a typical pathogen-associated molecular pattern (PAMP), β-1,3-glucan can engage with pattern recognition receptors (PRRs) to initiate an immune response.
Tailei Xu, Junbao Wang, Hao Xu, Zifan Wang, Yujie Liu, Hongfeng Bai, Yixiang Zhang, Youqin Kong, Yan Liu, Zhili Ding   +9 more
doaj   +1 more source

Impact of changes at the Candida albicans cell surface upon immunogenicity and colonisation in the gastrointestinal tract

The Cell Surface, 2022
The immunogenicity of Candida albicans cells is influenced by changes in the exposure of microbe-associated molecular patterns (MAMPs) on the fungal cell surface. Previously, the degree of exposure on the C.
Gabriela M. Avelar, Ivy M. Dambuza, Liviana Ricci, Raif Yuecel, Kevin Mackenzie, Delma S. Childers, Judith M. Bain, Arnab Pradhan, Daniel E. Larcombe, Mihai G. Netea, Lars P. Erwig, Gordon D. Brown, Sylvia H. Duncan, Neil A.R. Gow, Alan W. Walker, Alistair J.P. Brown   +15 more
doaj   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Comparative analysis of β-glucan content in wild and cultivated barley (Hordeum vulgare)

The Indian Journal of Agricultural Sciences, 2018
β-glucan is an important element found in cereal cell walls, which is tremendously beneficial to human health and significant in industrial produce.
MUTHANTHIRIGE DON, LALITH CHANDARA NISHANTHA, XIAN ZHAO, DIDDUGODAGE CHAMILA JEEWANI, GUANGWEI XING, JIANXIN BIAN, XIAOJUN NIE, WEINING SONG   +7 more
doaj   +1 more source

Effect of β-glucan-induced trained immunity on leptospirosis.

, 2019
(A) Survival curves of hamsters in the infected control group (n = 8), the β-glucan control group (n = 8) and the group stimulated with β-glucan and leptospires (n = 8). Hamsters were stimulated with β-glucan 5 days prior to leptospira challenge.
Dianjun Wu (3603755), Zhao Jin (1559038), Wenlong Zhang (283123), Yongguo Cao (469062), Ning Song (533762), Jiaqi Wang (369548), Xufeng Xie (3603758), Tianbao Lv (7645727)   +7 more
core   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1

Cell Reports, 2020
Summary: β-glucan is a potent inducer of epigenetic and functional reprogramming of innate immune cells, a process called “trained immunity,” resulting in an enhanced host response against secondary infections.
Simone J.C.F.M. Moorlag, Nargis Khan, Boris Novakovic, Eva Kaufmann, Trees Jansen, Reinout van Crevel, Maziar Divangahi, Mihai G. Netea   +7 more
doaj   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Characterization of β-glucan obtained from Candida albicans of caprine mastitis

Open Veterinary Journal
Background: Beta-glucan (β-glucan) is a polysaccharide containing β-glycosidic bonds that is an important structure part of different yeast cells.
Saddam Hussein Mahmoud, Shaimaa Nabhan Yassein   +1 more
doaj   +1 more source