Results 211 to 220 of about 753,928 (305)

The Diagnostic Odyssey of a Biochemically Confirmed Case of ML II: The First Western Patient With LYSET Deficiency

Clinical Genetics, Volume 110, Issue 1, Page 125-130, July 2026.
We identify a female patient with a homozygous nonsense variant (p.Gln38Ter) in the LYSET gene. This is the first western report of a challenging case of an extensive diagnostic odyssey and demonstrates that the LYSET gene must be considered in the differential diagnosis when M6P‐labeled lysosomal enzymes are altered.
Fernanda Sperb‐Ludwig, Taciane Alegra, Leonardo Martinello da Rosa, Nataniel Floriano Ludwig, Renata Voltolini Velho, Ida Vanessa Doederlein Schwartz   +5 more
wiley   +1 more source

β‑Glucosidase Discovery and Design for the Degradation of Oleuropein

ACS Omega, 2018
Kathryn G. Guggenheim, Lauren M. Crawford, Francesca Paradisi, Selina C. Wang, Justin B. Siegel   +4 more
doaj   +1 more source

Neutron crystallography of the covalent intermediate of β-glucosidase reveals remodeling of the catalytic center. [PDF]

Proc Natl Acad Sci U S A
Yano N, Kashima T, Arakawa H, Lin CC, Ishiwata A, Namiki H, Takaya N, Tanaka K, Kusaka K, Fushinobu S.   +9 more
europepmc   +1 more source

Efficacy and safety of switching to iGlarLixi from premixed insulin therapy in patients with type 2 diabetes: A real‐world experience

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Aims Fixed‐ratio combinations such as iGlarLixi are recommended over premixed insulin as first‐line injectable therapy for type 2 diabetes mellitus (T2DM), yet real‐world evidence on transitions from premix to iGlarLixi remains limited. This study aimed to evaluate the efficacy and safety of switching from premixed insulin to iGlarLixi in a ...
Chun‐Jui Huang, Shun‐Jie Yang, Cheng‐Pin Cheng, Chun‐Hsing Lin, Ya‐Chun Lee, Harn‐Shen Chen   +5 more
wiley   +1 more source

Computational Insights into Glucose Tolerance and Stimulation in a Family 1 β-glucosidase. [PDF]

J Chem Inf Model
Dias AHS, Skaf MS, Silveira RL.
europepmc   +1 more source

A systematic review and meta‐analysis of the relative benefit of dual versus single oral hypoglycaemic therapy following diagnosis with type 2 diabetes (T2D)

Diabetic Medicine, Volume 43, Issue 7, July 2026.
Abstract Introduction Achieving and sustaining target glycated haemoglobin (HbA1c) levels is fundamental in the management of type 2 diabetes (T2D). We here aimed to assess whether initial dual oral therapy outperforms monotherapy in reaching glycaemic targets in patients with treatment‐naive or early‐stage T2D.
Mairead Kelly, Sushant Saluja, Hugh Logan Ellis, Sarah Jamil, Martin B. Whyte, Adrian Heald   +5 more
wiley   +1 more source

Impact of Changes in Buffer Ionic Concentration and Mutations on a GH1 β‑Glucosidase Homodimer. [PDF]

ACS Omega
Chagas RS, Marana SR.
europepmc   +1 more source

Bifidobacterium bifidum G9‐1 Intake Improves Gastrointestinal Symptoms in Type 2 Diabetes Mellitus: An Open‐Label, Randomized Controlled Trial (Binary STAR Study)

Diabetes, Obesity and Metabolism, Volume 28, Issue 7, Page 5952-5967, July 2026.
ABSTRACT Aims To evaluate the effects of probiotics Bifidobacterium bifidum G9‐1 (BBG9‐1) on gastrointestinal symptoms in patients with Type 2 diabetes mellitus (T2DM) with diarrhoea or constipation. Materials and Methods In a 12‐week open‐label randomised controlled trial, 100 participants were randomized 1:1 to a control or BBG9‐1 group, with 12 mg ...
Genki Kobayashi, Yoshitaka Hashimoto, Tomoyuki Matsuyama, Noriyuki Kitagawa, Saori Majima, Takafumi Senmaru, Emi Ushigome, Hiroshi Okada, Naoko Nakanishi, Masahide Hamaguchi, Michiaki Fukui   +10 more
wiley   +1 more source

Characterization of Recombinant GH 43 β-Xylosidases and a GH 3 β-Glucosidase from <i>Levilactobacillus brevis</i> for the Hydrolysis of Lignocellulose-Derived Substrates. [PDF]

J Microbiol Biotechnol
Vasquez R, Mendoza RM, Cañas VA, Song JH, Lee JS, Bagon B, Kang DK.   +6 more
europepmc   +1 more source

Long‐Term Cultivation of Perennial Energy Crops Enhance Ecosystem Multifunctionality on Marginal Red Soil Without Trade‐Offs

GCB Bioenergy, Volume 18, Issue 7, July 2026.
Switchgrass (SG) and Miscanthus (MS) boost ecosystem multifunctionality in marginal soils. Strong synergies, not trade‐offs, exist among ecosystem services under SG and MS. MS surpasses SG in provisioning and supporting services for higher multifunctionality. MS is ideal for maximizing multifunctionality, carbon sequestration, and stability.
Yini Wu (伍旖旎), Yi Xu (许依), Tongcheng Fu (傅童成), Meng Li (李蒙), Moritz von Cossel, Grant Campbell, Pete Smith, Yasir Iqbal, Zili Yi (易自力), Shuai Xue (薛帅)   +9 more
wiley   +1 more source