Results 11 to 20 of about 937,622 (274)
Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Hadfield, Peter S. +4 more
core +5 more sources
Spherical and rod shaped protoplasts from β-lactam antibiotic treated cultures of Bacillus subtilis [PDF]
Addition of β-lactams to exponentially growing cultures of an autolytically deficient Bacillus subtilis metc3 lyt-2 strain FJ6 caused increase in optical density to stop after 1 h when it had about doubled, and thereafter to remain constant for at least 6 h.
G. Wright, H.J. Rogers
openaire +1 more source
NMR spectrometric assay for determining enzymatic hydrolysis of β-lactam antibiotics with bacteria in aqueous solution [PDF]
An application of a nuclear magnetic resonance (NMR) spectrometer for the measurement of β-lactamase activity in clinical material containing bacteria is presented. By means of proton (1H)-NMR, it was easy to measure quantitatively β-lactamase activity in human bacteriuria, without performing any such pretreatment as isolation of bacteria or extraction
Koji O'hara, Yoko Shiomi, Megumi Kono
openaire +1 more source
The state and consideration for skin test of β-lactam antibiotics in pediatrics
β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao +3 more
doaj +1 more source
Initiation of murein biosynthesis inEscherichia colicells treated with β-lactam antibiotics [PDF]
The study of the synthesis and accumulation of murein in cells initiating growth in the presence of β-lactam antibiotics indicated: (i) Murein rearrangement contributes substantially to cell enlargement during the first doubling in cell mass; (ii) Penicillin-binding protein 2 has the potential capability to synthesize most, if not all, the new murein ...
Antonio G. Pisabarro +3 more
openaire +1 more source
β-Lactam vs Non-β-Lactam Antimicrobial Prophylaxis and Surgical Site Infection.
Importance β-lactam-based surgical antimicrobial prophylaxis (SAP) is the standard for most surgical procedures. Alternatively, and mostly due to allergies, non-β-lactam-based prophylaxis is used.
Largiadèr S +8 more
europepmc +2 more sources
Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer +3 more
doaj +1 more source
PREPARATION OF ANTIBACTERIAL BENTONITE β LACTAM ANTIBIOTIC COMPOSITE
The adsorption of Doripenem (beta-lactam antibiotic belonging to the subgroup carbapenem) from aqueous solution using bentonite as the adsorbent was studied at various pH of the solution. The doripenem loaded in bentonite which called doripenem-bentonite
Gladdy Waworuntu +4 more
doaj +1 more source
Background β-lactam antibiotics are a class of broad-spectrum antibiotics consisting of all antibiotic agents that contain a β-lactam ring in their molecular structures. β-lactam antibiotics are only known to be isolated from fungi (e.g.
Tiffany Turner +3 more
doaj +1 more source
The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
core +3 more sources

