Results 11 to 20 of about 87,683 (298)
An update on the synthesis and reactivity of spiro-fused β-lactams [PDF]
Arkivoc, 2018 Beta-Lactam ring-containing compounds play a pivotal role in drug design and synthetic chemistry. Spirocyclic beta-lactams, representing an important beta-lactam subclass, have recently attracted considerable interest with respect to new synthetic ...
D'hooghe, Matthias, Dao Thi, Hang
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Giant linear plasmids of β-lactam antibiotic producing Streptomyces [PDF]
FEMS Microbiology Letters, 1995 A survey of the total cellular DNA from five β-lactam antibiotic-producing Streptomyces spp. by pulsed field gel electrophoresis was conducted to investigate the presence of linear plasmids. Streptomyces clavuligerus NRRL 3585 contained two giant linear plasmids of 120 and 430 kb, in addition to the well-characterized 11.7 kb linear plasmid ...
Donald J. Netolitzky +3 more
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A method to transform the β-lactam antibiotic producerStreptomyces wadayamensis [PDF]
FEMS Microbiology Letters, 1986 We have developed a transformation system for Streptomyces wadayamensis, a cephamycin C producer. 1−5 × 109 protoplasts can be obtained when late logarithmic phase cultures of this microorganisms are incubated with 10 mg/ml of lysozyme. Polyethylene glycol-Ca2+-mediated transformation of these protoplasts yielded 106 transformants per μg of pIJ702 or ...
C. Acebal, V. Rubio, G. Márquez
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Spherical and rod shaped protoplasts from β-lactam antibiotic treated cultures of Bacillus subtilis [PDF]
FEMS Microbiology Letters, 1988 Addition of β-lactams to exponentially growing cultures of an autolytically deficient Bacillus subtilis metc3 lyt-2 strain FJ6 caused increase in optical density to stop after 1 h when it had about doubled, and thereafter to remain constant for at least 6 h.
G. Wright, H.J. Rogers
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Initiation of murein biosynthesis inEscherichia colicells treated with β-lactam antibiotics [PDF]
FEMS Microbiology Letters, 1987 The study of the synthesis and accumulation of murein in cells initiating growth in the presence of β-lactam antibiotics indicated: (i) Murein rearrangement contributes substantially to cell enlargement during the first doubling in cell mass; (ii) Penicillin-binding protein 2 has the potential capability to synthesize most, if not all, the new murein ...
Antonio G. Pisabarro +3 more
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Stereoselective cyanation of 4-formyl and 4-imino-?-lactams: application to the synthesis of polyfunctionalized ?-lactams [PDF]
Tetrahedron, 2012 Peer ...
Alcaide, Benito +3 more
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NMR spectrometric assay for determining enzymatic hydrolysis of β-lactam antibiotics with bacteria in aqueous solution [PDF]
FEMS Microbiology Letters, 1984 An application of a nuclear magnetic resonance (NMR) spectrometer for the measurement of β-lactamase activity in clinical material containing bacteria is presented. By means of proton (1H)-NMR, it was easy to measure quantitatively β-lactamase activity in human bacteriuria, without performing any such pretreatment as isolation of bacteria or extraction
Koji O'hara, Yoko Shiomi, Megumi Kono
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Allergy, Asthma & Clinical Immunology, 2020 Background Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsistent.
Philipp Schrüfer +3 more
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Safety of Cefazolin in Prophylaxis in Β-Lactam Allergic Children
Bezmiâlem Science, 2022 Objective:Cefazolin is a first-generation cephalosporin, particularly effective against gram positive agents such as staphylococci and streptococci. Despite this narrow spectrum, it is important in surgical prophylaxis.
Ayşe SÜLEYMAN +3 more
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BMC Complementary Medicine and Therapies, 2021 Background β-lactam antibiotics are a class of broad-spectrum antibiotics consisting of all antibiotic agents that contain a β-lactam ring in their molecular structures. β-lactam antibiotics are only known to be isolated from fungi (e.g.
Tiffany Turner +3 more
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