Results 131 to 140 of about 52,668 (245)

Gel electrofocusing combined with zymogram techniques for the characterization of β-lactamases from gram negative bacteria [PDF]

FEMS Microbiology Letters, 1977
B. Olsson, C.-E. Nord, T. Wadström, B. Wretlind   +3 more
openaire   +1 more source

MOESM1 of Single nucleotide polymorphisms in genes encoding penicillin-binding proteins in β-lactamase-negative ampicillin-resistant Haemophilus influenzae in Japan

, 2018
Additional file 1. Reference sequences used in this study.
Misawa, Kazuhisa, Tarumoto, Norihito, Tamura, Shinsuke, Morichika Osa, Hamamoto, Takaaki, Yuki, Atsushi, Kouzaki, Yuji, Imai, Kazuo, Runtuwene Ronald, Yamaguchi, Toshiyuki, Murakami, Takashi, Shigefumi Maesaki, Suzuki, Yutaka, Kawana, Akihiko, Maeda, Takuya   +14 more
openaire   +1 more source

Enhancing diabetic foot osteomyelitis diagnosis with metagenomics next‐generation sequencing, proof of concept

Diabetic Medicine, Volume 43, Issue 4, April 2026.
The use of mNGS with the MinION tool clearly provides a significant advantage compared to routine culture by identifying a higher diversity of pathogens in diabetic foot osteomyelitis. It also highlights the value of this method in clinical decision making, despite the technical challenges inherent in metagenomic sequencing.
Madjid Morsli, Chloé Magnan, Florian Salipante, Adeline Dubois, Sophie Schuldiner, Nicolas Cellier, Albert Sotto, Jean‐Philippe Lavigne, Catherine Dunyach‐Remy   +8 more
wiley   +1 more source

The depletion of serine beta‐lactamase‐like protein (LACTB) ameliorates metabolic dysfunction–associated steatotic liver disease by reducing ubiquitin‐mediated degradation of carnitine palmitoyltransferase 2

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 2962-2977, April 2026.
Abstract Aims Metabolic dysfunction–associated steatotic liver disease (MASLD) represents one of the most common chronic liver disorders worldwide, and its incidence continues to rise each year. Serine β‐lactamase‐like protein (LACTB) is a serine protease that plays a crucial role in lipid metabolism and hepatocellular carcinoma, but its function in ...
Wujiang Shi, Xin Liu, Nan Wang, Qianwen Zhang, Jianjun Gao, Canghai Guan, Yapeng Li, Chengru Yang, Shaowu Bi, Xinlei Zou, Xiangyu Zhong   +10 more
wiley   +1 more source

Emphysematous Pyelonephritis After Embolization of a Nonfunctioning Kidney Graft

Nephrology, Volume 31, Issue 4, April 2026.
ABSTRACT Emphysematous pyelonephritis (EPN) is a rare but severe infection with a high mortality rate characterised by gas formation within the renal parenchyma. Although primarily affecting native kidneys, EPN may exceptionally develop in nonfunctioning renal allografts.
Marina Arnaiz, Marta Alonso, Carlos Narváez, Florentino Villanego, Luis Alberto Vigara, Rodrigo García‐Baquero, Teresa García, José Luis Álvarez‐Ossorio, Auxiliadora Mazuecos   +8 more
wiley   +1 more source

Multiscale Hybrid Surface Topographies Orchestrate Immune Regulation, Antibacterial Defense, and Tissue Regeneration

Advanced Healthcare Materials, Volume 15, Issue 11, 20 March 2026.
Hybrid wrinkled topographies coordinate immune, tissue, and bacterial interactions. The surfaces promote osteointegration, tune macrophage polarization, and inhibit biofilm formation, highlighting a multifunctional strategy for next‐generation implant design.
Mohammad Asadi Tokmedash, Jacob Robins, J. Scott VanEpps, Minji Kim, Jouha Min   +4 more
wiley   +1 more source

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, Volume 13, Issue 16, 18 March 2026.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, Volume 13, Issue 14, 9 March 2026.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Isolation and characterisation of the potent broad spectrum β-lactamase AME 1 from Streptomyces antibioticus ssp. Antibioticus [PDF]

FEMS Microbiology Letters, 1983
A.M. Erne, H. Zähner, R.G. Werner
openaire   +1 more source

Programming Next‐Generation Synthetic Biosensors by Genetic Circuit Design

Advanced Science, Volume 13, Issue 14, 9 March 2026.
Synthetic biology enables genetic circuit‐based biosensing to detect diverse targets, process signals, and transduce them into readable outputs or intracellular regulatory activities. However, field deployment and real‐world application of such synthetic biosensors face considerable challenges in sensitivity, specificity, speed, stability, and ...
Yuanli Gao, Cheng Huang, Jiaxuan Deng, Lei Wang, Baojun Wang   +4 more
wiley   +1 more source