Results 71 to 80 of about 52,668 (245)

MIC profiling of ceftazidime/avibactam against two carbapenemase-producing Klebsiella pneumoniae isolates

Journal of Global Antimicrobial Resistance, 2020
Objectives: The aim of this study was to correlate the results of a modified susceptibility testing method with outcomes of ceftazidime/avibactam (CAZ/AVI) therapy. Methods: Two bloodstream K.
Andrei Zidaru, Brianna M. Eales, Weiqun Wang, Paul R. Merlau, Todd M. Lasco, Amelia K. Sofjan, Vincent H. Tam   +6 more
doaj   +1 more source

MOESM2 of Molecular characterization of β-lactamase genes in clinical isolates of carbapenem-resistant Acinetobacter baumannii

, 2017
Additional file 2: Table S2. Primer sequences used for A. baumannii in present study.
Raible, Kevin, Bhaswati Sen, Law, Nancy, Bias, Tiffany, Emery, Christopher, Ehrlich, Garth, Joshi, Suresh   +6 more
openaire   +1 more source

Anterolateral‐Thigh Fascia Lata Free Flap Versus Fibula Free Flap for Mandibular Osteoradionecrosis

The Laryngoscope, EarlyView.
The anterolateral thigh fascia lata “rescue” free flap has been employed as a novel tool in the treatment of advanced partial thickness mandibular osteoradionecrosis. Compared with the traditional fibula free flap for the same indication, the “rescue” flap provides similar outcomes in terms of disease resolution, superior functional outcomes, and ...
Conrad K. Blunck, Alexander Havens, Michael A. Fritz, Brandon L. Prendes, Derek J. Vos, Amani Alvi, Sara Liu, Dane J. Genther, Peter J. Ciolek   +8 more
wiley   +1 more source

Expanding the β‐Lactamase Family in the Human Microbiome

Advanced Science
β‐lactams, the most common antibiotics globally, have resistance primarily determined by β‐lactamases. Human microbiota and β‐lactams influence mutually; however, β‐lactamase variety and abundance in the human microbiome remain partially understood. This
Baolei Jia, Ju Hye Baek, Jae Kyeong Lee, Ying Sun, Kyung Hyun Kim, Ji Young Jung, Che Ok Jeon   +6 more
doaj   +1 more source

Incidence of Urinary Tract Infection After Combined Cystoscopy and Urodynamic Testing: A Prospective Cohort Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To evaluate the incidence of urinary tract infection (UTI) after combined cystoscopy and urodynamic testing. Methods A prospective analytical cohort study was conducted including adult patients undergoing cystoscopy, urodynamic testing, or both procedures during the same session at a quaternary referral center between May 1, 2023 ...
Camilo Andres Torres Sandoval, María Juliana Arcila, Andrés Duarte Osorio, Juan Guillermo Cataño, Sebastian Peña Rodriguez   +4 more
wiley   +1 more source

Structure-guided drug repurposing identifies aristospan as a potential inhibitor of β-lactamase: insights from virtual screening and molecular dynamics simulations

Frontiers in Pharmacology
The rise of β-Lactamase mediated antibiotic resistance is a major concern for public health; hence, there is an urgent need to find new treatment approaches.
Moyad Shahwan, Moyad Shahwan, Mohd Shahnawaz Khan, Azna Zuberi, Nojood Altwaijry, Anas Shamsi   +5 more
doaj   +1 more source

Human metallo-β-lactamase enzymes degrade penicillin

Scientific Reports, 2019
Nonribosomal peptides are assemblages, including antibiotics, of canonical amino acids and other molecules. β-lactam antibiotics act on bacterial cell walls and can be cleaved by β-lactamases.
Seydina M. Diene, Lucile Pinault, Vivek Keshri, Nicholas Armstrong, Saber Khelaifia, Eric Chabrière, Gustavo Caetano-Anolles, Philippe Colson, Bernard La Scola, Jean-Marc Rolain, Pierre Pontarotti, Didier Raoult   +11 more
doaj   +1 more source

Modifying Antibiotic Activity of Synthetic Thiadiazine Analogs Against MDR Bacteria and ADMET Analysis

ChemistryOpen, EarlyView.
The study demonstrated that thidiazine compounds potentiated the action of antibiotics. The compounds associated with norfloxacin against S. aureus showed greater significance in relation to the other medications. The indiscriminate use of antibiotics has led to the selection of resistant bacterial strains, significantly reducing the effectiveness of ...
João Arthur de Oliveira Borges, Priscilla Ramos Freitas, Isaac Moura Araújo, Ray Silva de Almeida, Igor José dos Santos Nascimento, João Xavier de Araújo‐Júnior, Edeildo Ferreira da Silva‐Júnior, Thiago Mendonça de Aquino, Francisco Jaime Bezerra Mendonça Junior, Emmanuel Silva Marinho, Hélcio Silva dos Santos, Radosław Kowalski, Grażyna Kowalska, Henrique Douglas Melo Coutinho, Saulo Relison Tintino, Ana Carolina Justino de Araújo   +15 more
wiley   +1 more source

Phenotypic Characterization and Antibiotic Resistance Patterns of Extended-Spectrum β-Lactamase- and AmpC β-Lactamase-Producing Gram-Negative Bacteria in a Referral Hospital, Saudi Arabia

Canadian Journal of Infectious Diseases and Medical Microbiology, 2019
Background. Emergence of pathogenic bacteria carrying β-lactamase-resistant determinants has become a major health problem in the hospital setting. The study aimed to determine antibiotic-resistant patterns and frequency of extended-spectrum β-lactamase-
Mutasim E. Ibrahim, Mohammed Abbas, Abdullah M. Al-Shahrai, Bahaeldin K. Elamin   +3 more
doaj   +1 more source

Green Synthesis of ZnO Nanoparticles From Spirulina platensis: Antimicrobial and Cytotoxic Evaluation With Molecular Docking Studies

ChemistryOpen, EarlyView.
Algal‐extract‐derived ZnO nanoparticles show shape anisotropy and are bio capped by phytochemicals. These green‐synthesized NPs strongly inhibit S. aureus and K. pneumoniae biofilms. Molecular docking suggests stable binding of surface biomolecules to microbial targets, highlighting synergistic antibacterial mechanisms.
Muhammad Rizwan, Izaz Khan, Syed Sikandar Shah, Amir hamza khan, Abdurahman Hajinur Hirad, Saira Naz, Arshad Farid, Taimoor Khan, Said Hassan   +8 more
wiley   +1 more source