iNew Medicine, EarlyView.ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah +5 more
wiley +1 more source
Comparative Evaluation of the in-vitro Activity of Six β-lactam/β-lactamase Inhibitor Combinations against Gram Negative Bacilli [PDF]
Journal of Clinical and Diagnostic Research, 2013 Background: The extensive use of the β-lactam antibiotics in hospitals and in the community has created major resistance problems which has led to increased morbidity, mortality and healthcare costs.
Smita Sood
doaj +1 more source
Construction by polymerase chain reaction and intragenic DNA probes for three main types of transferable β-lactamases (TEM, SHV, CARB) [PDF]
FEMS Microbiology Letters, 1991 Intragenic DNA probes were synthesized by polymerase chain reaction using fragments of the genes of three major types of β-lactamases (TEM, SHV, CARB) as templates. The TEM probe hybridized with the genes encoding TEM-1, TEM-2 and six extended-spectrum related enzymes (TEM-3 to TEM-7, TEM-20) in colony hybridizations and Southern-blot analysis. The SHV
G. Arlet, A. Philippon
openaire +1 more source
Consequences of revised CLSI and EUCAST guidelines for antibiotic susceptibility patterns of ESBL- and AmpC β-lactamase-producing clinical Enterobacteriaceae isolates [PDF]
, 2017 Objectives This study aimed to: (i) analyse the antibiotic susceptibility testing (AST) profiles of extended spectrum β-lactamase (ESBL)- and AmpC β-lactamase-producing clinical Enterobacteriaceae isolates applying EUCAST 2013 AST guidelines; and (ii ...
Bloemberg, Guido V. +2 more
core +1 more source
Detection of SHV β-lactamases in Gram-negative bacilli using fluorescein-labeled antibodies [PDF]
, 2009 Background β-lactam resistance in Gram-negative bacteria is a significant clinical problem in the community, long-term care facilities, and hospitals. In these organisms, β-lactam resistance most commonly results from the production of β-lactamases.
Bethel Christopher R +5 more
core +1 more source
Potent monoclonal antibodies against multidrug‐resistant hypervirulent Klebsiella pneumoniae
Interdisciplinary Medicine, EarlyView.A novel immunization strategy using a low‐virulence, multidrug‐resistant strain yields synergistic monoclonal antibodies against hypervirulent Klebsiella pneumoniae. These antibodies provide cross‐serotype protection through a dual‐mechanism of pathogen clearance and immunomodulation, offering a promising non‐antibiotic therapeutic for resistant ...
Yushan Jiang +10 more
wiley +1 more source
mSphereβ-Lactam antibiotics and β-lactamase inhibitor combinations are essential for combating antimicrobial resistance, with many β-lactams, including clavulanic acid (CA), themselves being products of specialized metabolic pathways in bacteria. CA is a potent
Kapil Tahlan +8 more
doaj +1 more source
Journal of Global Antimicrobial Resistance, 2020 Objectives: The aim of this study was to correlate the results of a modified susceptibility testing method with outcomes of ceftazidime/avibactam (CAZ/AVI) therapy. Methods: Two bloodstream K.
Andrei Zidaru +6 more
doaj +1 more source
Development of an improved Pseudoalteromonas haloplanktis TAC125 strain for recombinant protein secretion at low temperature [PDF]
, 2008 Background: In a previous paper, we reported the accomplishment of a cold gene-expression system for the recombinant secretion of heterologous proteins in Pseudoalteromonas haloplanktis TAC125.
CIRULLI C. +3 more
core +1 more source