Results 71 to 80 of about 54,914 (224)

Comparative Evaluation of the in-vitro Activity of Six β-lactam/β-lactamase Inhibitor Combinations against Gram Negative Bacilli [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2013
Background: The extensive use of the β-lactam antibiotics in hospitals and in the community has created major resistance problems which has led to increased morbidity, mortality and healthcare costs.
Smita Sood
doaj   +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

open access: yes
American Journal of Hematology, EarlyView.
Elisa Buzzatti   +25 more
wiley   +1 more source

Interpretation of Key Updates in the 36th Edition of Clinical and Laboratory Standards Institute M100 Standard

open access: yesiLABMED, EarlyView.
ABSTRACT The Clinical and Laboratory Standards Institute M100 document serves as a cornerstone standard for clinical microbiology laboratories in China. Maintaining the scientific rigor of its predecessors, the 36th edition incorporates updated epidemiological cutoff values, pharmacokinetic/pharmacodynamic data, and clinical efficacy evidence to revise
Kanghong Xu, Qi Wang, Hui Wang
wiley   +1 more source

Antarctic soil microbiomes encode structurally conserved and phylogenetically diverse beta‐lactamases

open access: yesiMetaOmics, EarlyView.
An integrative metagenomic framework combining sequence, structural, and functional inference reveals a phylogenetically diverse and structurally conserved repertoire of putative beta‐lactamases across Antarctic soil microbiomes, with predominance of class A and subclass B3 enzymes and limited but detectable associations with mobile genetic elements ...
José Coche‐Miranda   +8 more
wiley   +1 more source

Functional insights into Streptomyces isolates containing both clavulanic acid-like and carbapenem biosynthetic gene clusters

open access: yesmSphere
β-Lactam antibiotics and β-lactamase inhibitor combinations are essential for combating antimicrobial resistance, with many β-lactams, including clavulanic acid (CA), themselves being products of specialized metabolic pathways in bacteria. CA is a potent
Kapil Tahlan   +8 more
doaj   +1 more source

MOESM2 of Investigation of urban birds as source of β-lactamase-producing Gram-negative bacteria in Marseille city, France

open access: yes, 2019
Additional file 2. Sampling details according to the investigated locations.
Ngaiganam, Edgarthe   +6 more
openaire   +1 more source

Antimicrobial susceptibility patterns of β-lactamase producing <i>Staphylococcus Aureus</i>

open access: yesJournal of Armed Forces Medical College, Bangladesh, 1970
doi:10.3329/jafmc.v4i2.1838JAFMC Bangladesh Vol.4(2) 2008 14 ...
Luthunnahar Khan   +5 more
openaire   +2 more sources

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

Expanding the β‐Lactamase Family in the Human Microbiome

open access: yesAdvanced Science
β‐lactams, the most common antibiotics globally, have resistance primarily determined by β‐lactamases. Human microbiota and β‐lactams influence mutually; however, β‐lactamase variety and abundance in the human microbiome remain partially understood. This
Baolei Jia   +6 more
doaj   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

open access: yesiNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah   +5 more
wiley   +1 more source

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