Results 121 to 130 of about 1,672,197 (320)
Journal of Hospital Medicine, EarlyView.Abstract Background Nursing and healthcare‐associated pneumonia (NHCAP) is defined as pneumonia occurring in individuals with frequent healthcare contact, such as residents of care facilities or patients with impaired activities of daily living. The effectiveness of broad‐spectrum antibiotics in treating NHCAP remains unclear.
Jumpei Taniguchi +4 more
wiley +1 more source
Detection of extended spectrum B-lactamases in urinary isolates of Klebsiella pneumoniae in relation to Bla SHV, Bla TEM and Bla CTX-M gene carriage [PDF]
, 2011 Background: Resistance to contemporary broad-spectrum β-lactam antibiotics mediated by extended-spectrum β-lactamases (ESBLs) is increasing worldwide.
Eftekhar, F. +3 more
core +1 more source
Cephalosporinases associated with outer membrane vesicles released by Bacteroides spp. protect gut pathogens and commensals against beta-lactam antibiotics [PDF]
, 2014 Objectives: To identify β-lactamase genes in gut commensal Bacteroides species and to assess the impact of these enzymes, when carried by outer membrane vesicles (OMVs), in protecting enteric pathogens and commensals.
Brearley, Charles +6 more
core +1 more source
, 2017 Additional file 2: Table S2. Primer sequences used for A. baumannii in present study.
Raible, Kevin +6 more
openaire +1 more source
Anterolateral‐Thigh Fascia Lata Free Flap Versus Fibula Free Flap for Mandibular Osteoradionecrosis
The Laryngoscope, EarlyView.The anterolateral thigh fascia lata “rescue” free flap has been employed as a novel tool in the treatment of advanced partial thickness mandibular osteoradionecrosis. Compared with the traditional fibula free flap for the same indication, the “rescue” flap provides similar outcomes in terms of disease resolution, superior functional outcomes, and ...
Conrad K. Blunck +8 more
wiley +1 more source
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli
Biomolecules, 2020 Resistance to β-lactam antibacterials, importantly via production of β-lactamases, threatens their widespread use. Bicyclic boronates show promise as clinically useful, dual-action inhibitors of both serine- (SBL) and metallo- (MBL) β-lactamases.
Pauline A. Lang +12 more
doaj +1 more source
Asp-120 Locates Zn2 for Optimal Metallo-β-lactamase Activity [PDF]
, 2007 Metallo-β-lactamases are zinc-dependent hydrolases that inactivate β-lactam antibiotics, rendering bacteria resistant to them. Asp-120 is fully conserved in all metallo-β-lactamases and is central to catalysis.
Bennett, Brian +5 more
core +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Objective To evaluate the incidence of urinary tract infection (UTI) after combined cystoscopy and urodynamic testing. Methods A prospective analytical cohort study was conducted including adult patients undergoing cystoscopy, urodynamic testing, or both procedures during the same session at a quaternary referral center between May 1, 2023 ...
Camilo Andres Torres Sandoval +4 more
wiley +1 more source
Repurposing of Meropenem and Nadifloxacin for Treatment of Burn Patients? [PDF]
, 2009 The escalating number of multidrug resistant pathogens has demanded the swift development of new and potent antibiotics (ref. 2). Metallo-[beta]-lactamases (MBLs) continue to evolve, rendering the latest generation of carbapenem antibiotics useless (ref.
Christie E. Costa +5 more
core +1 more source
Multi-drug resistant Gram-negative bacteria: antibiotic-resistance and new treatment strategies [PDF]
, 2017 In this editorial, we treat the multi-drug-resistance of microorganisms such as Klebsiella pneumonia (Kp) and Acinetobacter baumanii and the issues concerning the management of these infections.
Angelis, Massimiliano De +2 more
core +1 more source