Results 131 to 140 of about 893,542 (154)

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

open access: yesCells, 2020
Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) to treat metabolic impairment induced by maternal and long ...
David A. Sinclair   +2 more
exaly   +2 more sources

Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN [PDF]

open access: yesFEBS Letters, 2002
The final step in the biosynthesis of nicotinamide-adenine dinucleotide, a major coenzyme in cellular redox reactions and involved in intracellular signaling, is catalyzed by the enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT).
Mathias Ziegler   +2 more
exaly   +2 more sources

Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns

open access: yesJournal of Advanced Research, 2022
BackgroundElderly population has been progressively rising in the world, thus the demand for anti-aging heath products to assure longevity as well as to ameliorate age-related complications is also on the rise.
Baohong Zhang   +2 more
exaly   +2 more sources

The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

open access: yesGeroScience, 2022
In animal studies, β-nicotinamide mononucleotide (NMN) supplementation increases nicotinamide adenine dinucleotide (NAD) concentrations and improves healthspan and lifespan with great safety.
Andrea Maier, Lin Yi
exaly   +2 more sources

Towards personalized nicotinamide mononucleotide (NMN) supplementation: Nicotinamide adenine dinucleotide (NAD) concentration

open access: yesMechanisms of Ageing and Development
Nicotinamide mononucleotide (NMN) is a precursor of nicotinamide adenine dinucleotide (NAD), which declines with age. Supplementation of NMN has been shown to improve blood NAD concentration. However, the optimal NMN dose remains unclear.
Pendse, Sohal   +11 more
exaly   +3 more sources

Home - About - Disclaimer - Privacy