β-Nicotinamide Mononucleotide Inhibits Cellular Senescence in Mouse C2C12 Skeletal Muscle Cells [PDF]
Journal of Aging Researchβ-Nicotinamide mononucleotide (NMN), as the precursor of nicotinamide adenine dinucleotide (NAD+), has remarkable therapeutic potential in aging-associated diseases.
Jing Mi +8 more
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Metabolic Engineering of Pseudomonas putida KT2440 for β-Nicotinamide Mononucleotide Biosynthesis from Glucose and Aspartate [PDF]
Microorganismsβ-Nicotinamide mononucleotide (NMN) is an important intermediate in nicotinamide adenine dinucleotide (NAD+) metabolism and has attracted increasing interest as a bioactive compound and biomanufacturing product.
Luna Gao +7 more
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Nicotinamide mononucleotide alleviates the streptozotocin-mediated ferroptosis of islet β-cells via the Nrf2/GPX4 pathway [PDF]
Brazilian Journal of Medical and Biological ResearchThe effects of nicotinamide mononucleotide (NMN) on streptozotocin (STZ)-induced islet β-cell dysfunction and the underlying mechanisms have not been fully elucidated.
Decheng Lu +4 more
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Safety of beta‐nicotinamide mononucleotide (β‐NMN) pursuant the regulation (EU) 2015/2283 and the bioavailability of nicotinamide from this source in the context of Directive 2002/46/EC [PDF]
EFSA JournalFollowing a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on beta‐nicotinamide mononucleotide (β‐NMN) as a novel food (NF) pursuant to Regulation (EU) 2015/2283 ...
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) +27 more
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Exploring the therapeutic potential of β-nicotinamide mononucleotide (NMN) in regulating canine NT-proBNP levels [PDF]
Journal of Advanced Veterinary and Animal ResearchObjectives: N-terminal pro–B-type natriuretic peptide (NT-proBNP) is a key biomarker for assessing cardiac function in companion animals and plays a critical role in the diagnosis and management of heart disease.
Zipeng Jiang, Liang Mei, Zhiyi Huang
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SelO-mediated nicotinamide adenine dinucleotide hydrolysis and its implications for metabolic therapies. [PDF]
Clin Transl MedClinical and Translational Medicine, Volume 16, Issue 8, August 2026.
Zhang T, Wang T, Fu Y.
europepmc +2 more sources
β-Nicotinamide mononucleotide preserves muscle strength in septic male mice [PDF]
Scientific ReportsSepsis remains a leading cause of mortality and long-term disability, with survivors frequently developing intensive care unit–acquired weakness (ICU-AW) as part of post-intensive care syndrome.
Mari Saida +8 more
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Anti-inflammatory effects of nicotinamide mononucleotide (NMN) in human skeletal muscle after BFR-exercise [PDF]
Journal of the International Society of Sports NutritionBackground β-Nicotinamide mononucleotide (NMN) inhibits acute inflammation in injured animal tissues.Aim We examined whether NMN supplementation attenuates inflammation induced by blood flow restriction-resistance exercise (BFR-exercise) in human ...
Dai-Lin Yang +10 more
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Metabolic Engineering of Escherichia coli for the Production of β-Nicotinamide Mononucleotide [PDF]
Shipin Kexue, 2023 A modular metabolic engineering for Escherichia coli was designed for efficient production of β-nicotinamide mononucleotide (β-NMN). First, eight enzymes involved in the shunt metabolic pathways of nicotinamide (NAM) and β-NMN were inactivated to reduce ...
AN Junxia, WANG Qianqian, WANG Zhaoying, LIU Huan, XU Qingyang, FAN Xiaoguang
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Advance in Understanding the Effect of β-Nicotinamide Mononucleotide on Physiological Functions [PDF]
Shipin Kexue, 2023 The overweight or obese population in sub-health status and the aging population in China are increasing year by year. The intracellular level of nicotinamide adenine dinucleotide (NAD+) decreases dramatically with age and obesity. NAD+ is the key target
CHEN Tao, CAO Hui, DONG Li, JI Zhe, CAO Jianmin
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