Results 141 to 150 of about 893,542 (163)

Brain-targeting lipid nanoparticles of nicotinamide mononucleotide: preparation, optimization, and characterization. [PDF]

Front Chem
Lin Y, Zhao F, Wang J, Ping S, Wu K, Chen Y, Zheng X, Xu H.   +7 more
europepmc   +1 more source

Deacetylation of SRF catalyzed by SIRT7 protects against abdominal aortic aneurysm formation. [PDF]

Exp Mol Med
Xiong Y, Chen J, Lu W, Liu Y, Sheng C, Liu S, Xu B, Li Y, Pan B, Wang W.   +9 more
europepmc   +1 more source

Endothelial C/EBPβ/AEP pathway drives vascular deterioration and systemic aging. [PDF]

Sci Adv
Li B, Nie S, Wang M, An J, Qian Z, Meng X, Edgington-Mitchell LE, Zhang Z, Yang X, Ye K.   +9 more
europepmc   +1 more source

Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers

Cells, 2020
Maternal obesity impacts offspring metabolism. We sought to boost mitochondrial energy metabolism using the nicotinamide adenine dinucleotide (NAD+) precursor nicotinamide mononucleotide (NMN) to treat metabolic impairment induced by maternal and long ...
David A. Sinclair, Sabiha S Chowdhury, Neil A Youngson   +2 more
exaly   +2 more sources

Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns

Journal of Advanced Research, 2022
BackgroundElderly population has been progressively rising in the world, thus the demand for anti-aging heath products to assure longevity as well as to ameliorate age-related complications is also on the rise.
Baohong Zhang, Harshani Nadeeshani, Jinyao Li   +2 more
exaly   +2 more sources

Crystal structure of human nicotinamide mononucleotide adenylyltransferase in complex with NMN [PDF]

FEBS Letters, 2002
The final step in the biosynthesis of nicotinamide-adenine dinucleotide, a major coenzyme in cellular redox reactions and involved in intracellular signaling, is catalyzed by the enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT).
Mathias Ziegler, Udo Heinemann, Manfred Schweiger   +2 more
exaly   +2 more sources

Towards personalized nicotinamide mononucleotide (NMN) supplementation: Nicotinamide adenine dinucleotide (NAD) concentration

Mechanisms of Ageing and Development
Nicotinamide mononucleotide (NMN) is a precursor of nicotinamide adenine dinucleotide (NAD), which declines with age. Supplementation of NMN has been shown to improve blood NAD concentration. However, the optimal NMN dose remains unclear.
Pendse, Sohal, Vaidya, Aditi, Thasma, Sornaraja, Kumbhar, Vidyadhar, Kuerec, Ajla Hodzic, Wang, Weilan, Lin, Zhigang, Avhad, Ganesh, Maier, Andrea B.; id_orcid, Yi, Lin, Tao, Rongsheng, Andhalkar, Niranjan   +11 more
exaly   +3 more sources

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Safety evaluation after acute and sub-chronic oral administration of high purity nicotinamide mononucleotide (NMN-C®) in Sprague-Dawley rats

Food and Chemical Toxicology, 2021
Laurent Laganier, Matthias Canault, Alessia Grozio   +2 more
exaly  

The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

GeroScience, 2022
Andrea Maier, Lin Yi
exaly  

Host–microbiome interactions in nicotinamide mononucleotide (NMN) deamidation

FEBS Letters, 2023
Lindsay E Wu, Greg Colin Smith, Lake-Ee Quek   +2 more
exaly