Results 11 to 20 of about 697,712 (159)
Carcinogenesis of β-Propiolactone: A Computational Study. [PDF]
Chem Res Toxicol, 2020 The discovery that β-propiolactone (BPL), once a commercially important chemical, causes various tumors in experimental animals has led to a significant decrease in its use.
Španinger E, Bren U.
europepmc +2 more sources
Viruses, 2023 Inactivated vaccines are promising tools for tackling the COVID-19 pandemic. We applied several protocols for SARS-CoV-2 inactivation (by β-propiolactone, formaldehyde, and UV radiation) and examined the morphology of viral spikes, protein composition of
Larisa V. Kordyukova +6 more
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Optimization of RHDV type 1 and 2 inactivation modes
Ветеринария сегодня, 2021 The purpose of these studies was to optimize RHDV type 1 and 2 (RHDV1 and RHDV2) inactivation modes to use the obtained antigens in inactivated vaccines and diagnosticums.
E. D. Kunikova +4 more
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Vaccines, 2021 Tilapia lake virus (TiLV) is a newly emerging pathogen responsible for high mortality and economic losses in the global tilapia industry. Currently, no antiviral therapy or vaccines are available for the control of this disease.
Weiwei Zeng +10 more
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The pivotal role of β-lactone stereochemistry in the development of SARS-CoV-2 M<sup>pro</sup> inhibitors. [PDF]
Protein SciAbstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Świderek K, Moliner V.
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When Bigger is Better: Lanthanum Complexes of Bis(phenoxy-amidine) FAlen Ligands as Unique Catalysts for the Isoselective Ring-Opening Polymerization of Racemic β-Lactones. [PDF]
Angew Chem Int Ed EnglDiscrete lanthanum complexes supported by new bis(phenoxy‐amidine) ligands act as highly efficient ring‐opening polymerization (ROP) catalysts of simple and functional β‐propiolactones rac‐BLR under mild conditions, returning in a controlled manner the corresponding linear polymers PBLR with high isoselectivity, no matter the nature and polarity of the
Bui TT +7 more
europepmc +3 more sources
Characterization and application of carboxylate-type zwitterions synthesized by one-step
Journal of Ionic Liquids, 2022 Zwitterions have been attracting great attention and the synthesis of carboxylate-type zwitterions is complicated than those of sulfonate-type zwitterions.
Tetsuo Komori +8 more
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Organocatalyzed Synthesis and Degradation of Functionalized Poly(4-allyloxymethyl--propiolactone)s [PDF]
, 2021 The chemical synthesis of degradable poly(β-hydroxyalkanoate) (PHA) produced by microorganisms allows the control of the solubility, crystallinity, hydrophobicity, degradability, thermal, and mechanical properties by introducing functionality on the ...
Minseong Kim +11 more
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Журнал микробиологии, эпидемиологии и иммунобиологии, 2021 Introduction. Cases of Chikungunya fever have been reported in more than 100 countries in Europe, Oceania, Africa, Asia, the Caribbean, and America. The musculoskeletal disorders typical for Chikungunya fever can last from several months to a year and ...
G. M. Ignatyev +4 more
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Viruses, 2022 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused huge social and economic distress. Given its rapid spread and the lack of specific treatment options, SARS-CoV-2 needs to be inactivated according to strict biosafety measures during
Shouzhi Yu +12 more
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