Results 1 to 10 of about 51,448 (177)

A novel HBD gene mutation associated with normal-range hb A2 in β-thalassemia carriers [PDF]

Annals of Hematology
β-thalassemia is one of the most common single-gene inherited conditions in the world, prevalence of β-thalassaemia in south China is 3–4%,increased Hb A2 level is one of the most important markers of β-thalassemia heterozygous carriers.Interaction of ...
Lei Zhang, Jingxin Yang, Xingping Li, Yang Liu, Chao Liu, Shan Duan, Lijun Zhang, Wenlan Liu, Ming Chang   +8 more
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The impact of the expression signatures of LncRNAs HBBP1 and XIST on the diagnostic significance of patients with β-Thalassemia [PDF]

Annals of Hematology
β-thalassemia is an inherited blood disorder with long-term associated complications. The purpose of this study was to evaluate the clinical significance of the lncRNA-HBBP1 and lncRNA-XIST expression profiles in the diagnosis of β-thalassemia patients ...
Abdallah M. Gameel, Shimaa Abdelsattar, Zeinab A. Kasemy, Mai El-Sayad Abd El-Hamid, Eman Masoud Abd ElGayed, Basma M. Abdelgawed, Amira Fathy El-Fiky, Mariam E. Labib, Sabry M. Abdelmageed, Mahmoud Ahmed El Hawy, Yasmin Mohsen, Hanan M. Bedair   +11 more
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Membranoproliferative glomerulonephritis in β-thalassemia intermedia; a case report [PDF]

Journal of Nephropathology, 2022
Introduction: β-thalassemia intermedia reduces the body’s ability to produce adult hemoglobin and causes anemia. In contrast to β-thalassemia major, β-thalassemia intermedia patients do not require lifelong transfusion and are often independent of blood ...
Maryam Shafiee, Seyed Alireza Zomorodian, Seyed Mohammad Owji, Jamshid Roozbeh Shahroodi, Mahsa Torabi Jahromi   +4 more
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Association Between KLF1, BCL11A and HBS1L‐MYB Polymorphisms and Phenotypes With β‐Thalassemia Patients in Hainan [PDF]

Molecular Genetics & Genomic Medicine
Background The factors influencing the phenotypic heterogeneity of patients with β‐thalassemia have been receiving much attention in the field of hematology research.
Junjie Hu, Huaye Chen, Wei Gong, Min Feng, Shidong Fu, Weihua Xu, Zhichao Ma, Shengmiao Fu, Xinping Chen   +8 more
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Changes in coagulation status in patients with β-thalassemia in Iraq: A case-control study

Medical Journal of Babylon, 2022
Background: The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF).
Hussein Abdalzehra Wadaha, Hassan Dede Meshay, Mohammed Haseeb Khamees   +2 more
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Compound Heterozygous Sickle Cell-β-Thalassemia: A Case Report from Upper Assam, India [PDF]

National Journal of Laboratory Medicine, 2016
Sickle cell-β-thalassemia [Hb S/β- thalassemia] is a rare type of hemoglobinopathy. The clinical characteristics of Hb S/β- thalassemia are highly variable from a completely asymptomatic state to a severe disorder like homozygous sickle cell disease.
Anju Barhai Teli , Rumi Deori , Sidhartha Protim Saikia , Bipul Ch. Kalita   +3 more
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A Prospective Study for the Outcomes of Thalassemia in Kirkuk 2016 [PDF]

Kirkuk Journal of Science, 2017
Background: Thalassemia is one of the most globally common chronic hematological disorder. This inherited disorder is characterized by an abnormal production of hemoglobin protein resulting in a life-threatening disease of two main types α and β.In ...
Asal Aziz Tawfeeq
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Molecular Spectrum, Ethnic and Geographical Distribution of Thalassemia in the Southern Area of Hainan, China

Frontiers in Pediatrics, 2022
BackgroundThalassemia is one of the most common genetic diseases in southern China. Accurate population frequency data regarding the occurrence and distribution of thalassemia are important for designing appropriate prevention strategies for thalassemia.
Ying Yu, Chunjiao Lu, Ying Gao, Cuiyun Li, Dongxue Li, Jie Wang, Jie Wang, Hui Wei, Zhaohui Lu, Zhaohui Lu, Guoling You, Guoling You   +11 more
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Molecular Characterization of α- and β-Thalassaemia Among Children From 1 to 10 Years of Age in Guangxi, A Multi-Ethnic Region in Southern China

Frontiers in Pediatrics, 2021
Background: Thalassemia is one of the most common genetic diseases in southern China. Howerver, population in different regions or different population has their own spectrums of thalassemia.
Sheng He, Dongming Li, Shang Yi, Xiuning Huang, Chaofan Zhou, Biyan Chen, Yangjin Zuo, Li Lin, Faqin Chen, Hongwei Wei   +9 more
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THE CORRELATION OF β/α MRNA RATIO WITH CLINICAL AND HEMATOLOGICAL PARAMETERS IN PATIENTS WITH β-THALASSEMIA SYNDROME

The Iraqi Journal of Medical Sciences, 2022
Background: Thalassemias are a group of genetically transmitted blood diseases characterized by defects in the production of α- or β-chains of hemoglobin called α-thalassemia and β-thalassemia, respectively.
May H. Yousif, Hind S. Al-Mamoori
doaj   +1 more source