Results 31 to 40 of about 42,354 (173)

Hematological Parameters in Individuals with Beta Thalassemia Trait in South Sumatra, Indonesia

Anemia, 2022
Background. β-Thalassemia has a very wide clinical variation, depending on the severity of the patient’s condition. Individuals with β-thalassemia traits are usually asymptomatic; however, laboratory examination will show mild anemia with microcytic ...
Dian Puspita Sari, Pustika Amalia Wahidiyat, Iswari Setianingsih, Ina S. Timan, Djajadiman Gatot, Aria Kekalih   +5 more
doaj   +1 more source

β-THALASSEMIA TRAIT MENGGUNAKAN ELEKTROFORESIS MIKROKAPILER

INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018
Thalassemia is a genetic disorder disease which spread in the different parts of the world, including Indonesia. The incidence of β-thalassemia trait in Indonesia is between 3−8%. The objective of this study is to know the incidence of β-thalassemia trait in studentswho performed medical check-up, which obtain by using capilary electrophoresis, to ...
Nuryanti Nuryanti, Ratna Akbari Ganie, Adi Koesoema Aman   +2 more
openaire   +2 more sources

Molecular understanding of unusual HbE-β+-thalassemia with Hb phenotype similar to HbE heterozygote: simple and rapid differentiation using HbE levels

Annals of Medicine, 2023
Background Low HbF expression in HbE-β+-thalassemia may lead to misdiagnosis of HbE heterozygosity. We aimed to characterize the β- and α-globin genes and the modifying factors related to HbF expression in patients with an Hb phenotype similar to that of
Wittaya Jomoui, Surada Satthakarn, Sitthichai Panyasai   +2 more
doaj   +1 more source

Prevalence and molecular characterization of common thalassemia among people of reproductive age in the border area of Guangxi-Yunnan-Guizhou province in Southwestern China

Hematology, 2022
Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent in southern China. Epidemiological and molecular characterization of thalassemia is important for designing appropriate prevention strategies in high-risk areas ...
GuiDan Xu, ChunFang Wang, JunLi Wang, Min Lin, ZhengYi Chang, JuHua Liang, XiaoHao Chen, ShiMao Zhong, XueJuan Nong, WuJun Wei, YiBin Deng   +10 more
doaj   +1 more source

The Associations between HLA DQB1 different Alleles and β-thalassemia Major [PDF]

Minia Journal of Medical Research, 2020
Thalassemias are the commonest inherited hemoglobinopathies in the world. Approximately 68,000 children are born with various thalassemia syndromes each year. β-Thalassemia represents a major public health problem in Egypt. beta thalassemia. It is caused
Amel Kamal Eldin, ,Emad Abd El Naem, Mostafa Elsayed, Nada Zaki Mahmoud   +3 more
doaj   +1 more source

Study of discriminant factor M/H ratio in screening for β thalassemia trait

IP Journal of Diagnostic Pathology and Oncology, 2020
Introduction: Beta Thalassemia syndrome is a group of hereditary disorders characterized by genetic deficiency in the synthesis of beta globin chains located on chromosome 11. A major diagnostic challenge is to differentiate between mild microcytic hypochromic anaemia due to BTT from other causes such as iron deficiency (IDA), sideroblastic anaemia etc.
openaire   +2 more sources

Co-Inheritance of Heterozygous β⁰-Thalassemia with Single Functional α-Globin Gene: Challenges of Carrier Detection in Pre-Marital Screening Program for Thalassemia

Thalassemia Reports, 2022
This is a report of a couple with abnormal hematological indices who were investigated for α & β-thalassemia mutations. Based on CBC and capillary hemoglobin electrophoresis results, the male and female subjects were β & α-thalassemia carriers ...
Hossein Jalali, Hossein Karami, Mohammad Reza Mahdavi, Mehrad Mahdavi   +3 more
doaj   +1 more source

The hypercoagulation state among major β-thalassemia patients at H. Adam Malik Hospital, Medan, Indonesia

Bali Medical Journal, 2019
Background: Thalassemia is the most common hereditary blood disorder in the world and Indonesia. Major β-thalassemia is classified as Transfusion-Dependent Thalassemia (TDT). Specific changes in the composition of red cell membrane lipids and hemosiderosis may lead to hypercoagulation.
Jane Tetraulina Silitonga, Adi Koesoema Aman, Bidasari Lubis   +2 more
openaire   +1 more source

Prevalence of B-Thalassemia Carriers Among a Cohort of University Students in Hawler Province of Iraqi Kurdistan

Iraqi Journal of Pharmaceutical Sciences ( P-ISSN: 1683 - 3597 , E-ISSN : 2521 - 3512), 2017
         A representative sample of a thousand volunteer university students was screened for evidence of thalassemia minor.Complete blood counts using automated blood cell analysers and blood smears were examined. Patients having anemia, abnormal red cell indices or morphological features of thalassemia minor like hypochromia, microcytosis, target ...
Abdulkadir A. Alnakshabandi, Huda A. Muhammad   +1 more
openaire   +3 more sources

MOESM1 of A validated cellular biobank for β-thalassemia

, 2016
Additional file 1: Table S1. List of the subjects (patients and healthy subjects) present in the Thal-Biobank.
Cosenza, Lucia, Breda, Laura, Breveglieri, Giulia, Zuccato, Cristina, Finotti, Alessia, Lampronti, Ilaria, Borgatti, Monica, Chiavilli, Francesco, Gamberini, Maria, Satta, Stefania, Manunza, Laura, Martis, Franca, Moi, Paolo, Rivella, Stefano, Gambari, Roberto, Bianchi, Nicoletta   +15 more
openaire   +1 more source