A novel HBD gene mutation associated with normal-range hb A2 in β-thalassemia carriers [PDF]
Annals of Hematologyβ-thalassemia is one of the most common single-gene inherited conditions in the world, prevalence of β-thalassaemia in south China is 3–4%,increased Hb A2 level is one of the most important markers of β-thalassemia heterozygous carriers.Interaction of ...
Lei Zhang +8 more
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The impact of the expression signatures of LncRNAs HBBP1 and XIST on the diagnostic significance of patients with β-Thalassemia [PDF]
Annals of Hematologyβ-thalassemia is an inherited blood disorder with long-term associated complications. The purpose of this study was to evaluate the clinical significance of the lncRNA-HBBP1 and lncRNA-XIST expression profiles in the diagnosis of β-thalassemia patients ...
Abdallah M. Gameel +11 more
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Membranoproliferative glomerulonephritis in β-thalassemia intermedia; a case report [PDF]
Journal of Nephropathology, 2022 Introduction: β-thalassemia intermedia reduces the body’s ability to produce adult hemoglobin and causes anemia. In contrast to β-thalassemia major, β-thalassemia intermedia patients do not require lifelong transfusion and are often independent of blood ...
Maryam Shafiee +4 more
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Changes in coagulation status in patients with β-thalassemia in Iraq: A case-control study
Medical Journal of Babylon, 2022 Background: The pathogenesis β-thalassemia is characterized by anemia resulting from reduced β-globin synthesis with low hemoglobin A (HbA) production and higher production of hemoglobin A2 (HbA2) and fetal hemoglobin (HbF).
Hussein Abdalzehra Wadaha +2 more
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Compound Heterozygous Sickle Cell-β-Thalassemia: A Case Report from Upper Assam, India [PDF]
National Journal of Laboratory Medicine, 2016 Sickle cell-β-thalassemia [Hb S/β- thalassemia] is a rare type of hemoglobinopathy. The clinical characteristics of Hb S/β- thalassemia are highly variable from a completely asymptomatic state to a severe disorder like homozygous sickle cell disease.
Anju Barhai Teli +3 more
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A Prospective Study for the Outcomes of Thalassemia in Kirkuk 2016 [PDF]
Kirkuk Journal of Science, 2017 Background: Thalassemia is one of the most globally common chronic hematological disorder. This inherited disorder is characterized by an abnormal production of hemoglobin protein resulting in a life-threatening disease of two main types α and β.In ...
Asal Aziz Tawfeeq
doaj +1 more source
Assessment of Molecular Changes of Transfusion Dependent Beta Thalassemia Children in El Minia Governorate and Their Correlations with Patients Clinical Outcomes [PDF]
Minia Journal of Medical Research, 2020 Beta Thalassemia represents a major public health problem in Egypt. The carrier rate varies between 5.5% to > 9%. It is estimated that there are 1000/1.5 million per year live births born with beta thalassemia.(1) β thalassemia occurs when there is a ...
, Aliaa Hegazi +3 more
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Investigating the level of Hba1c and insulin level in β-thalassemia patients
MEDISAINS: Jurnal Ilmiah Ilmu-Ilmu Kesehatan, 2023 Background: β-thalassemia is an inherited blood disorder characterized by reduced or no synthesis of β globin chain, resulting in chronic anemia, so blood transfusion is required as curative therapy. Repeated blood transfusions lead to iron overload that can lead to multiple organ damage, including pancreatic organs.Objective: This study aimed to ...
Husnan Mujiburrahman +4 more
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Frontiers in Pediatrics, 2022 BackgroundThalassemia is one of the most common genetic diseases in southern China. Accurate population frequency data regarding the occurrence and distribution of thalassemia are important for designing appropriate prevention strategies for thalassemia.
Ying Yu +11 more
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Vitamin D, Calcium and Phosphor in Patients with β-Thalassemia Major [PDF]
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2019 There has been many reports that patients with β-thalassemia major have bone problems such as thinning of the bone, bone fragility and pathological fractures. For so many years it was believed that the bone problems is mainly caused by marrow expansion due to compenstation of the bone marrow to handle the chronic anaemia and hiypoxia in β-thalassemia
Ade Hariza Harahap +2 more
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