Results 21 to 30 of about 51,483 (212)
Majalah Kedokteran Bandung, 2015 Iron overload is the common cause of morbidity and mortality in severe β-thalassemia patients. Many factors influence the iron status in severe β-thalassemia.
Susi Susanah, Ponpon Idjradinata
doaj +1 more source
Interaction of Hb South Florida (codon 1; GTG→ATG) and HbE, with β-thalassemia (IVS1-1; G→A): expression of different clinical phenotypes [PDF]
, 2009 Introduction: Interactions of different hemoglobin variants with thalassemia alleles can result in various clinical phenotypes. HbE-β-thalassemia generally manifests with severe anemia where individuals exhibit β-thalassemia major with regular blood ...
Chan, Lee Lee +5 more
core +1 more source
Efficacy of lactoferrin oral administration in the treatment of anemia and anemia of inflammation in pregnant and non-pregnant women: an interventional study [PDF]
, 2018 The discovery of the ferroportin-hepcidin complex has led to a critical review on the treatment of anemia and anemia of inflammation (AI). Ferroportin, the only known mammalian iron exporter from cells to blood, is negatively regulated by hepcidin, a ...
Antimo Cutone +6 more
core +2 more sources
Hematological Parameters in Individuals with Beta Thalassemia Trait in South Sumatra, Indonesia
Anemia, 2022 Background. β-Thalassemia has a very wide clinical variation, depending on the severity of the patient’s condition. Individuals with β-thalassemia traits are usually asymptomatic; however, laboratory examination will show mild anemia with microcytic ...
Dian Puspita Sari +5 more
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Hematology, 2022 Objectives: Thalassemia, the most common global monogenetic disorder, is highly prevalent in southern China. Epidemiological and molecular characterization of thalassemia is important for designing appropriate prevention strategies in high-risk areas ...
GuiDan Xu +10 more
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β-THALASSEMIA TRAIT MENGGUNAKAN ELEKTROFORESIS MIKROKAPILER
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY, 2018 Thalassemia is a genetic disorder disease which spread in the different parts of the world, including Indonesia. The incidence of β-thalassemia trait in Indonesia is between 3−8%. The objective of this study is to know the incidence of β-thalassemia trait in studentswho performed medical check-up, which obtain by using capilary electrophoresis, to ...
Nuryanti Nuryanti +2 more
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Analysis of Gγ-158(C→T) polymorphism in hemoglobin E/β-thalassemia major in Southern China [PDF]
, 2010 Background The Gγ-158(C→T) polymorphism plays important function in the clinical variability of HbE/β-thalassemia. There is little known about Gγ-158(C→T) polymorphism in HbE/β-thalassemia major in Southern China.
Rong Liu, Ming Wang, Yong Lai
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Annals of Medicine, 2023 Background Low HbF expression in HbE-β+-thalassemia may lead to misdiagnosis of HbE heterozygosity. We aimed to characterize the β- and α-globin genes and the modifying factors related to HbF expression in patients with an Hb phenotype similar to that of
Wittaya Jomoui +2 more
doaj +1 more source
Oxidative stress and age-related changes in T cells: Is thalassemia a model of accelerated immune system aging? [PDF]
, 2016 Iron overload in β-thalassemia major occurs mainly due to blood transfusion, an essential treatment for β-thalassemia major patients, which results in oxidative stress. It has been thought that oxidative stress causes elevation of immune system senescent
Asadi-Samani, Majid. +5 more
core +2 more sources
A Comparison of Intelligence Quotient in Children with and without β-Thalassemia Major
Galen Medical Journal, 2015 Background: Thalassemia is the most common hemoglobinopathy worldwide. Children with β-thalassemia major have several risk factors for cognitive problems. The aim of this study is to evaluate intelligence quotient in children with β-thalassemia major and healthy counterparts using Wechsler Intelligence Scale.
Samaneh Homayouni Meymandi +2 more
openaire +2 more sources