Results 151 to 160 of about 4,401,008 (278)

Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC

Hepatology, EarlyView., 2022
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu, Bingqing Xu, Xiaodong Wang, Wen‐Hua Wan, Jinying Lu, Deyuan Kong, Yu Jin, Wenhua You, Hua Sun, Xiaoxin Mu, Dongju Feng, Yun Chen   +11 more
wiley   +1 more source

Emerging Materials and Future Strategies for Solid Oxide Electrochemical Cells

Advanced Energy Materials, EarlyView.
Solid oxide electrochemical cells operate under strongly coupled electrochemical and thermodynamic conditions, where performance is constrained by interactions among crystal structure, defect chemistry, and interfacial evolution. This review, based on a structure‐defect‐property‐durability framework, reveals the roles of lattice symmetry and defect ...
Qiuchun Lu, Yufei Zhang, Han Zhao, Pooi See Lee, Daniel H.C. Chua   +4 more
wiley   +1 more source

Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma

Hepatology, EarlyView., 2022
Steatotic HCC can be diagnosed by MRI and forms a pro‐tumor immune microenvironment with high expression of PD‐L1, M2 polarization of macrophages and activation of CAFs, which may be a good target for combined immunotherapy. Abstract Background and Aims Immunotherapy has become the standard‐of‐care treatment for hepatocellular carcinoma (HCC), but its ...
Hiroki Murai, Takahiro Kodama, Kazuki Maesaka, Shoichiro Tange, Daisuke Motooka, Yutaka Suzuki, Yasuyuki Shigematsu, Kentaro Inamura, Yoshihiro Mise, Akio Saiura, Yoshihiro Ono, Yu Takahashi, Yota Kawasaki, Satoshi Iino, Shogo Kobayashi, Masashi Idogawa, Takashi Tokino, Tomomi Hashidate‐Yoshida, Hideo Shindou, Masanori Miyazaki, Yasuharu Imai, Satoshi Tanaka, Eiji Mita, Kazuyoshi Ohkawa, Hayato Hikita, Ryotaro Sakamori, Tomohide Tatsumi, Hidetoshi Eguchi, Eiichi Morii, Tetsuo Takehara   +29 more
wiley   +1 more source

Methods for Setting Device Specifications for Analog In‐Memory Computing Inference

Advanced Intelligent Systems, EarlyView.
Non‐volatile memories (NVMs) are being developed for analog in‐memory computing for energy‐efficient, high‐speed deep learning inference. As technology is moving to industry adoption, a method to define required NVM specifications is critical for improving performance and reducing manufacturing cost.
Zhenyu Wu, Xin Su, Malte J. Rasch, Ning Li   +3 more
wiley   +1 more source

Ultrasound–Calcination Synergistic Control of (Ce, La)PO4 Catalyst Structure for Enhanced Low‐Temperature NH3‐SCR Performance

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT In this study, (Ce, La)PO4 catalysts were synthesized via an ultrasound‐assisted method. The effects of ultrasound duration and calcination temperature on the low‐temperature NH3‐SCR performance were systematically investigated. The results indicated that the (Ce, La)PO4 catalyst prepared with an ultrasound treatment time of 20 min and a ...
Na Li, Kai Yan, Shuning Tan, Ruifang Wang, Zhiyu Zhang   +4 more
wiley   +1 more source

Inter‐microscope comparability of dental microwear texture data obtained from different optical profilometers: Part I Reproducibility of diet inference using different instruments

The Anatomical Record, EarlyView.
Abstract Dental microwear texture analysis (DMTA) has become a well‐established method for dietary inference and reconstruction in both extant and extinct mammals and other tetrapods. As the volume of available data continues to grow, researchers could benefit from combining published data from various studies to perform meta‐analyses.
Daniela E. Winkler, Mugino O. Kubo
wiley   +1 more source

Unraveling ovarian histology: The key morphological aspects that spur the development of the Fossa ovarii in equine

The Anatomical Record, EarlyView.
Abstract The equine ovary exhibits unique structural and developmental features that distinguish it from those of other domestic species, including the presence of an ovulation fossa and an inversion of cortical and medullary layers. This study aimed to investigate the morphostructural development of the equine fetal ovary, with particular emphasis on ...
Laura Ver Goltz, Silvio Pires Gomes, Bruno Cesar Schimming, Fabio Cesar Magioli Abdala, Maria Angélica Miglino, Tais Harumi de Castro Sasahara   +5 more
wiley   +1 more source

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

T cells, the next big target in axSpA?

Arthritis &Rheumatology, Accepted Article.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells.
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

A probiotic bacterium modulates antitumour γδ T-cell responses in lung cancer. [PDF]

Front Immunol
Goto Y, Dolton G, Thomas H, Morin T, Tajima Y, Imamura K, Sakata S, Oka K, Hayashi A, Takahashi M, Ueno T, Sakagami T, Tomita Y, Sewell AK, Motozono C.   +14 more
europepmc   +1 more source