Results 141 to 150 of about 33,979 (285)
Exploiting fundamental γδ T cell immunobiology in cancer immunotherapy
Immunotherapies such as immune checkpoint blockade (ICB) and chimeric antigen receptorT (CAR-T) cells, have transformed the therapeutic landscape of cancer, but have predominantly impacted certain malignancies/patient groups, with major areas of unmet ...
Willcox, Benjamin, Willcox, Carrie
core +1 more source
Advanced Energy Materials, EarlyView.A Gd‐doped Cu2O electrocatalyst disrupts rigid interfacial hydrogen‐bonding networks, creating a free‐water‐rich microenvironment. This accelerates proton‐coupled electron transfer, enabling selective high‐rate CO2‐to‐ethanol conversion with 48.5% Faradaic efficiency at industrially relevant current densities.
Hyunwoo Kim +11 more
wiley +1 more source
Angewandte Chemie, EarlyView.Hsf1 undergoes phase separation around target DNA, activating stress‐responsive transcription. DNA binding tunes conformational dynamics of Hsf1DBD, which propagates through large‐scale domain rearrangements involving DBD–IDR interactions to regulate phase separation. This hierarchical framework illustrates how local structural events at the side chain
Soichiro Kawagoe +2 more
wiley +2 more sources
Characterization of normal human CD3+ CD5- and γδ T cell receptor positive T lymphocytes
, 1990 SUMMARY The functional and phenotypic properties of normal human CD3+ CD5- T cells which have a higher frequency of cytotoxic cells than CD3+CD5+ T lymphocytes have been described.
E F SROUR +5 more
core +1 more source
Pesticide MRLs as Trade Barriers: Evidence From Vietnam's Coffee and Rice Exporters
Agribusiness, EarlyView.ABSTRACT As tariffs have declined globally through bilateral and regional trade agreements, food safety standards have emerged as significant determinants of agricultural trade flows. This study examines the impact of maximum residue limits (MRLs) for five pesticides—Azoxystrobin, Chlorpyrifos, Chlorantraniliprole, Clothianidin, and Cyhalothrin—on ...
Nhat Mai Nguyen +2 more
wiley +1 more source
Angewandte Chemie, EarlyView.A deep‐red‐excited osmium(II) photosensitizer (Os2) induces immunogenic cell death (ICD) under 740 nm irradiation and triggers robust anti‐tumor immune responses both in vitro and in vivo. ABSTRACT Immunogenic cell death (ICD), which converts tumor cells into their own vaccine, plays a pivotal role in the development of novel anticancer therapies. Here,
Yiyi Zhang +12 more
wiley +2 more sources
Recent Advances in Functional Liver Volumetry: Emphasis on 99mTc‐GSA SPECT/CT Fusion Imaging
Annals of Gastroenterological Surgery, EarlyView.Functional liver volumetry enables more accurate assessment of the future liver remnant by integrating anatomical and functional information, improving risk stratification before major hepatectomy. Among available techniques, 99mTc‐GSA SPECT/CT fusion imaging enables precise regional functional assessment and more reliable prediction of post ...
Toru Beppu +4 more
wiley +1 more source
Human γδ T cells in the tumor microenvironment: Key insights for advancing cancer immunotherapy
Molecules and Cells: The role of γδ T cells in antitumor responses has gained significant attention due to their major histocompatibility complex (MHC)-independent killing mechanisms, which are functionally distinct from conventional αβ T cells.
Won Hyung Park, Heung Kyu Lee
doaj +1 more source
The Role of the Gut Microbiota in Allogeneic Hematopoietic Cell Transplantation
American Journal of Hematology, EarlyView.ABSTRACT Allogeneic hematopoietic cell transplantation (allo‐HCT) is an effective treatment for patients with high‐risk hematologic malignancies. Over the last decade, gut microbiota composition during allo‐HCT has been associated with patients' outcomes.
Wenjing Hao +4 more
wiley +1 more source
Long-lived central memory γδ T cells confer protection against murine cytomegalovirus reinfection.
PLoS PathogensThe involvement of γδ TCR-bearing lymphocytes in immunological memory has gained increasing interest due to their functional duality between adaptive and innate immunity.
Nathalie Yared +17 more
doaj +1 more source