Results 51 to 60 of about 31,118 (247)
The co-stimulatory effects of MyD88-dependent Toll-like receptor signaling on activation of murine γδ T cells. [PDF]
PLoS ONE, 2014 γδ T cells express several different toll-like receptor (TLR)s. The role of MyD88- dependent TLR signaling in TCR activation of murine γδ T cells is incompletely defined. Here, we report that Pam3CSK4 (PAM, TLR2 agonist) and CL097 (TLR7 agonist), but not
Jinping Zhang +12 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine +40 more
wiley +1 more source
eLifeDuring thymic development, most γδ T cells acquire innate-like characteristics that are critical for their function in tumor surveillance, infectious disease, and tissue repair.
Somen K Mistri +11 more
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Frontiers in Immunology, 2020 Gamma delta (γδ) T cells kill transformed cells, and increased circulating γδ T cells levels correlate with improved outcome in cancer patients; however, their function within the breast tumor microenvironment (TME) remains controversial.
Gabrielle M. Siegers +6 more
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Arthritis Care &Research, Accepted Article.Objective High body mass index (BMI≥27 kg/m2) and aberrant gait biomechanics are primary risk factors for knee osteoarthritis (KOA), yet the specific loading patterns linked to clinical disease features remain unclear. Unsupervised machine learning (ML) was used to identify vertical ground reaction force (vGRF) waveform modes of variation and ...
Ashley N. Buck +10 more
wiley +1 more source
Heterogeneous characteristics of γδ T cells in peripheral blood of diffuse large B-cell lymphoma
Biomarker ResearchBackground Diffuse large B-cell lymphoma (DLBCL) is a highly heterogeneous disease with variable clinical and molecular features. Studies have highlighted the significant role of γδ T cells in the survival of leukemia patients. However, the heterogeneity
Peng-Lin Wang +7 more
doaj +1 more source
Compensatory mechanisms in γδ T cell-deficient chickens following Salmonella infection
Frontiers in ImmunologyAvian γδ T lymphocytes are highly abundant in the intestinal mucosa and play a critical role in immune defense against infectious diseases in chickens. However, their specific contributions to infection control remain poorly understood.
Felix Tetzlaff +7 more
doaj +1 more source
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.
PLoS ONE, 2015 Thymic development of αβ T lymphocytes into invariant natural killer (NK) T cells depends on their selection via agonistic lipid antigen presented by CD1d. If successful, newly selected NKT cells gain effector functions already in the thymus.
Inga Sandrock +6 more
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Advanced Functional Materials, EarlyView.Schematic illustration of the engineered RN@FDT for multimodal tumor therapy. a) Fabrication of FD&DOX/TFA‐loaded RGD‐NNV (RN@FDT) and the light‐triggered disassemble of RN@FDT. b) After internalized by tumor cells, RN@FDT are disintegrated under NIR‐II laser irradiation to boost PTT and induce cell apoptosis.
Jiahui Zhang +16 more
wiley +1 more source
γδ T cells confer protection against murine cytomegalovirus (MCMV).
PLoS Pathogens, 2015 Cytomegalovirus (CMV) is a leading infectious cause of morbidity in immune-compromised patients. γδ T cells have been involved in the response to CMV but their role in protection has not been firmly established and their dependency on other lymphocytes ...
Camille Khairallah +13 more
doaj +1 more source