Assessment of Heparanase-Mediated Angiogenesis Using Microvascular Endothelial Cells: Identification of λ-Carrageenan Derivative as a Potent Anti Angiogenic Agent [PDF]
Marine Drugs, 2017 Heparanase is overexpressed by tumor cells and degrades the extracellular matrix proteoglycans through cleavage of heparan sulfates (HS), allowing pro-angiogenic factor release and thus playing a key role in tumor angiogenesis and metastasis.
Nicolas Poupard +11 more
doaj +3 more sources
λ-Carrageenan P32 Is a Potent Inhibitor of Rabies Virus Infection. [PDF]
PLoS ONE, 2015 Rabies, caused by rabies virus (RABV), is an acute, fatal encephalitic disease that affects many warm-blooded mammals. Currently, post-exposure prophylaxis regimens are effective for most rabies cases, but once the clinical signs of the disease appear ...
Zhaochen Luo +11 more
doaj +3 more sources
A λ-Carrageenan-Enriched Sulfated Galactan from Gigartina radula Attenuates Atopic Dermatitis via Coordinated Anti-Inflammatory and Immunomodulatory Mechanisms [PDF]
Marine DrugsAtopic dermatitis (AD) is a chronic, relapsing inflammatory skin disease driven by immune dysregulation and epidermal barrier dysfunction. Current therapeutic options are often limited by safety concerns or suboptimal tolerability.
Kexin Du +8 more
doaj +2 more sources
Comparative analysis of different macromolecular crowding agents in human tenocyte cultures [PDF]
Biomaterials and BiosystemsTendon engineered substitutes remain clinically unavailable, largely due to the need for prolonged culture periods to allow for sufficient extracellular matrix deposition.
Andrea Rossoni +3 more
doaj +2 more sources
ChemFoodChemThis study explores the formation of insoluble biopolyelectrolyte complexes based on blackberry anthocyanin (BAE) and λ‐carrageenan (λ‐CRG). It aims to optimize the conditions that promote complexation between anthocyanin (ANC) molecules and λ ...
Tomás Garrido +5 more
doaj +2 more sources
Advances in Carrageenases: Molecular Engineering, Immobilization Techniques, and Biomedical Potential of Carrageenan Oligosaccharides [PDF]
Marine DrugsCarrageenan is a sulfated polysaccharide extracted from red algae, widely utilized in the food and pharmaceutical industries due to its unique gelling properties and biological activities.
Qiangzhuang Xie +7 more
doaj +2 more sources
Influence of λ-Carrageenan Induced Gut Microbiota Disorder on Glucose Metabolism of Mice(λ-卡拉胶诱导的肠道菌群紊乱对小鼠糖代谢的影响) [PDF]
Shipin kexue jishu xuebao, 2023 Carrageenan is a common food additive, but its effect on changing the structure of gut microbiota was questioned. In this study, the C57BL/6 mice were given three dosages of λ-carrageenan, including low, medium and high dose (1.7,8.3,41.7mg/kg) for 12 ...
ZHAI Leilei(翟雷雷) +5 more
doaj +1 more source
The complete λ-carrageenan depolymerization cascade from a marine Pseudoalteromonad revealed by structural analysis of the enzymes. [PDF]
J Biol ChemCarrageenans are a complex group of polysaccharides derived from the cell walls of red macroalgae. They are an abundant, yet recalcitrant nutrient source for most marine heterotrophic bacteria.
Vickers CJ +10 more
europepmc +2 more sources
Frontiers in Sustainable Food Systems, 2022 Phycocyanin is a protein-chromophore structure present in Arthrospira platensis commonly used as a blue-colorant in food. Color losses of phycocyanin can be reduced by electrostatic complexation with λ-carrageenan.
Stephan Buecker +4 more
doaj +1 more source
Carbohydrate Polymer Technologies and Applications, 2022 Packaging manufactured from petroleum is stable, and its waste threatens marine life. This study proposes the use of harmless edible materials manufactured from marine plants. Carrageenan is among the natural polysaccharides derived from red algae. Water
Natsumi Hirota, Kazukiyo Nagai
doaj +1 more source