The novel Sinupret® dry extract exhibits anti-inflammatory effectiveness in vivo [PDF]
Sinupret® is frequently used as a herbal medicinal product to treat sinusitis, and it was assumed that anti-inflammatory effects might contribute to its overall beneficial properties. Here, we investigated the effects of a Sinupret® drug mixture (SIN) as
Dehm F. +5 more
core +1 more source
Discovery of prostamide F2α and its role in inflammatory pain and dorsal horn nociceptive neuron hyperexcitability. [PDF]
It was suggested that endocannabinoids are metabolized by cyclooxygenase (COX)-2 in the spinal cord of rats with kaolin/λ-carrageenan-induced knee inflammation, and that this mechanism contributes to the analgesic effects of COX-2 inhibitors in this ...
Luisa Gatta +6 more
doaj +1 more source
Background and aim: Psoriasis (Ps) is a chronic skin inflammatory disorder, that progresses to scaly-red dermal plaque formations associated with inflammation.
Acharya Balkrishna +7 more
doaj +1 more source
Assembly PCR synthesis of optimally designed, compact, multi-responsive promoters suited to gene therapy application [PDF]
MRC-DTA studentship award British Pharmacological Society Integrative ...
AC Carpentier +53 more
core +2 more sources
Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive processing in rat pain models [PDF]
Background: Harnessing the actions of the resolvin pathways has the potential for the treatment of a wide range of conditions associated with overt inflammatory signalling.
Bennett, Andrew +4 more
core +5 more sources
Structural optimization and biological evaluation of 2-substituted 5-hydroxyindole-3-carboxylates as potent inhibitors of human 5-lipoxygenase. [PDF]
Pharmacological suppression of leukotriene biosynthesis by inhibitors of 5-lipoxygenase (5-LO) is a strategy to intervene with inflammatory and allergic disorders.
BÜHRING U +8 more
core +1 more source
Local Skin Inflammation in Cutaneous Leishmaniasis as a Source of Variable Pharmacokinetics and Therapeutic Efficacy of Liposomal Amphotericin B. [PDF]
Disfiguring skin lesions caused by several species of the Leishmania parasite characterize cutaneous leishmaniasis (CL). Successful treatment of CL with intravenous (i.v.) liposomal amphotericin B (LAmB) relies on the presence of adequate antibiotic ...
Alavijeh, Mo +7 more
core +2 more sources
DNA immunization has been used to study vaccination methods and for production of specific antibodies. The present study aimed to apply DNA immunization to prepare specific IgYs, which react against rabies virus N protein (RV-N) and can be used to ...
Nanase Kubo +4 more
doaj +1 more source
A Sensitive Gait Parameter for Quantification of Arthritis in Rats
Quantification of arthritis is helpful for investigating pain mechanisms of arthritis and for developing new drugs. We assessed and identified a feasible parameter for quantification of rat arthritis using a novel gait analyzing system.
Kensuke Orito +5 more
doaj +1 more source
In Vitro and In Vivo Anti-Inflammatory Potential of Cannabichromene Isolated from Hemp
Cannabichromene (CBC), a non-psychoactive cannabinoid found in Cannabis sativa, has recently been shown to possess several medicinal properties. However, how CBC produces anti-inflammatory effects and the mechanisms of this remain poorly studied ...
Min Hong +9 more
doaj +1 more source

