Results 61 to 70 of about 19,726 (227)
Journal of Pharmacological Sciences, 2014 The rewarding effects of μ-receptor agonists can be suppressed under several pain conditions. We recently showed that clinically used μ-receptor agonists possess efficacies for relieving the neuropathic pain induced by chemotherapeutic drug in rats ...
Tomohisa Mori +10 more
doaj +1 more source
Activation of the μ‐opioid receptor by alicyclic fentanyls: Changes from high potency full agonists to low potency partial agonists with increasing alicyclic substructure [PDF]
, 2020 Anna Åstrand +5 more
openalex +1 more source
Individualism and working from home
Economic Inquiry, EarlyView.Abstract We show that culturally transmitted individualism is an important determinant of working from home (WFH). Using individual‐level data from the U.S. Current Population Survey (CPS) and the European Social Survey (ESS), we compare immigrants and their descendants from different cultural backgrounds residing in the same location.
Jan Bietenbeck +2 more
wiley +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow +2 more
wiley +1 more source
Bidirectional Regulation of Opioid and Chemokine Function
Frontiers in Immunology, 2020 The opioid family of GPCRs consists of the classical opioid receptors, designated μ-, κ-, and δ-opioid receptors, and the orphanin-FQ receptor, and these proteins are expressed on both neuronal and hematopoietic cells.
Thomas J. Rogers
doaj +1 more source
Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys
Equine Veterinary Journal, EarlyView.Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno +6 more
wiley +1 more source
Journal of Child Psychology and Psychiatry, Volume 66, Issue 4, Page 516-546, April 2025.Proliferation of the term “emotion dysregulation” in child psychopathology parallels the growing interest in processes that influence negative emotional reactivity. While it commonly refers to a clinical phenotype where intense anger leads to behavioral dyscontrol, the term implies etiology because anything that is dysregulated requires an impaired ...
Joseph C. Blader +2 more
wiley +1 more source
Neuropeptide oxytocin enhances μ opioid receptor signaling as a positive allosteric modulator
Journal of Pharmacological Sciences, 2018 Oxytocin (OT) is a 9-amine neuropeptide that plays an essential role in mammalian labor, lactation, maternal bonding, and social affiliation. OT has been reported to exert an analgesic effect in both humans and animals, and the results of certain animal ...
Yoshiyuki Meguro +15 more
doaj +1 more source
Critical Assessment of G Protein-Biased Agonism at the μ-Opioid Receptor [PDF]
, 2020 Alexander Gillis +6 more
openalex +1 more source
Older Age Is Associated With Long‐Term Retention in Buprenorphine Treatment for Opioid Use Disorder
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Opioid use disorder (OUD) among older adults is a fast‐growing public health problem. However, little is known about treatment outcomes among older adults in office‐based buprenorphine programs. Thus, our objective was to examine how age is associated with buprenorphine treatment outcomes among adults with OUD who initiate ...
Justina L. Groeger +11 more
wiley +1 more source