Results 81 to 90 of about 19,726 (227)
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Gastroparesis is a chronic gastric motility disorder marked by delayed gastric emptying in the absence of mechanical obstruction. For patients with symptoms refractory to medical and dietary therapy, Gastric Peroral Endoscopic Myotomy (G‐POEM) has emerged as a minimally invasive, pylorus‐targeted intervention that directly addresses pyloric ...
Kobina Essilfie‐Quaye +6 more
wiley +1 more source
Binding Pathways of a G-Protein Biased μ-opioid Receptor agonist under Clinical Evaluation [PDF]
, 2016 Sebastian Schneider +2 more
openalex +1 more source
Investigation on μ-opioid receptor in Sera of Iraqi Male addiction Tramadol or Methamphetamine
, 2021 Rulla Sabah +2 more
openalex +1 more source
Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions
MedComm, Volume 7, Issue 2, February 2026.Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian +8 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 1, February 2026.ABSTRACT The concurrent use of opioids and benzodiazepines (BZDs) has raised safety concerns due to increased risks of respiratory depression and death. To evaluate mortality risks linked to different patterns of co‐prescription, we conducted a retrospective cohort study using data from a private hospital system between 2008 and 2018.
Fang‐Yu Su +3 more
wiley +1 more source
CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.ABSTRACT Loperamide is a widely used nonprescription peripherally acting opioid indicated for diarrhea. Loperamide undergoes extensive first‐pass metabolism, primarily by cytochrome (CYP) 3A and CYP2C8, with minor contributions from CYP2B6 and CYP2D6, and intestinal efflux by P‐glycoprotein (P‐gp).
Zhu Zhou +6 more
wiley +1 more source
Differential modulation of κ and μ opioid antinociception by the glycine/NMDA receptor agonist D‐serine [PDF]
, 1994 John C. Hunter +3 more
openalex +1 more source
United European Gastroenterology Journal, Volume 14, Issue 1, February 2026.ABSTRACT Background and aims No medications are currently approved for the prevention of recurrent acute pancreatitis. This trial evaluated whether naldemedine, a peripherally acting μ‐opioid receptor antagonist, reduces the risk of acute pancreatitis in patients with recurrent acute pancreatitis. Methods This was a multicentre, double‐blinded, placebo‐
Mathias E. Cook +13 more
wiley +1 more source
Peptidases Prevent μ-Opioid Receptor Internalization in Dorsal Horn Neurons by Endogenously Released Opioids [PDF]
, 2003 Bingbing Song, Juan Carlos G. Marvizón
openalex +1 more source
Effective management of chronic lumbar back pain in five dogs using an erector spinae plane block
Veterinary Record Case Reports, Volume 14, Issue 1, February 2026.Abstract This retrospective case series evaluates the use of the ultrasound‐guided erector spinae plane block for managing chronic lumbar pain in five dogs unresponsive to conventional systemic analgesia. Each patient received a bilateral erector spinae plane block at either the L2/L3 or L3/L4 level under general anaesthesia. The injectate consisted of
Nathalie Haslinger, Katrin Ertelt
wiley +1 more source