Results 11 to 20 of about 353 (81)
FREQUENCIES OF POLYMORPHISMS IN THE CYTOCHROME’S P450 GENES OF WARFARIN TRANSFORMATION IN A EUROPEAN POPULATION OF EASTERN SIBERIA [PDF]
Background. Genotypes of the cytochrome p450 isoform (CYP2C9 and CYP4F2) determine warfarin dose requirements. Frequencies of risk alleles and genotypes of CYP2C9 and CYP4F2 gene vary in different races and ethnic groups.Aim.
T. A. Bairova +14 more
doaj +3 more sources
The role of pharmacogenetics in Efficacy and safety of protease inhibitor based therapy in human immunodeficiency virus type (HIV) infection. [PDF]
Antiretroviral therapy has markedly reduced morbidity and mortality for persons living with human immunodeficiency virus (HIV). HIV can now be classified as a chronic disease; until a cure is found, patients are likely to require life-long therapy ...
A. Yu. Sambyalova +3 more
doaj +3 more sources
Pharmacogenetics of antiepileptic drugs (literature review) [PDF]
The article presents modern concepts of genes, polymorphisms which can influence the pharmacological response of the patient receiving antiepileptic drugs.
E. . Bochanova
doaj +2 more sources
Рекомендации по применению фармакогенетического тестирования в клинической практике [PDF]
Клиническая фармакогенетика — это раздел клинической фармакологии и клинической генетики, изучающий место и роль генетических факторов в формировании ответа организма человека на лекарственные средства (ЛС): эффективность, не эффективность, развитие ...
doaj +2 more sources
Сочетание алкогольнойзависимости и депрессии:трудности и особенности терапии
Депрессия встречается у 25–40 % пациентов с алкогольной зависимостью (АЗ). Несмотря на эффективность фармакотерапии при раздельно существующих АЗ и депрессии, применение лекарственных средств при коморбидной патологии недостаточно протестировано и ...
Николишин, Е. +4 more
doaj +1 more source
Pharmacogenetics of hypoglycemic agents [PDF]
Despite the increase in the number of hypoglycemic agents, 35%–40% of patients with diabetes are unable to achieve adequate glycemic control. One of the reasons is the genetic heterogeneity of diabetes mellitus, requiring different treatment approaches ...
Aleksandr Yuryevich Mayorov +3 more
core +3 more sources
PHARMACOGENETIC ASPECTS OF THE USE OF PERIOPERATIVE DRUGS IN PEDIATRICS. Review [PDF]
Relevance. It is known that in children the frequency of perioperative critical events due to the introduction of drugs is more than 5%. For example fentanyl, which is used as an adjunct to surgical anesthesia, is a major factor in increasing the number ...
M.V. Khaitovych +2 more
core +2 more sources
Фармакогенетика антиэпилептических препаратов [PDF]
There are some generalized data on a problem pharmacogenetics researches antiepileptic drugs on the basis of the analysis of the accessible native and foreign literature in this review.В настоящем обзоре на основе анализа отечественной и зарубежной ...
D. V. Dmitrenko +5 more
core +2 more sources
Pharmacogenetics of chemical addictions [PDF]
An overview of a number of research papers examines application of pharmacogenetic tests in narcology. It has been proven that a system of pharmacogenetic tests can be used for the development of a polygenic predictive system which can provide a ...
A. R. Asadullin +2 more
core +2 more sources
The clinical significance of the patient genetic characteristics in the individual pharmacological response to oral anticoagulants is considered. Possible tactics of warfarin dosing and new oral anticoagulants choice on the basis of pharmacogenetic ...
D. A. Sychev +3 more
doaj +1 more source

