Results 11 to 20 of about 12,711 (166)
Use of carrion fly iDNA metabarcoding to monitor invasive and native mammals
Conservation Biology, Volume 37, Issue 5, October 2023., 2023 Abstract Severely fragmented habitats increase the risk of extirpation of native mammal populations through isolation, increased edge effects, and predation. Therefore, monitoring the movement of mammal populations through anthropogenically altered landscapes can inform conservation. We used metabarcoding of invertebrate‐derived DNA (iDNA) from carrion
Kristen Fernandes +5 more
wiley +1 more source
Journal of Diabetes, Volume 15, Issue 5, Page 382-396, May 2023., 2023 HighlightsAutophagy is closely related to retinal neurovascular units in diabetes retinopathy. Different cells participate in the occurrence and development of diseases through autophagy, and targeted autophagy may be a new direction of treatment in the future. Emphasized the close relationship between diabetic retinopathy (DR) and autophagy Summarized
Xiongyi Yang +6 more
wiley +1 more source
Mechanisms of diabetic foot ulceration: A review 糖尿病足溃疡发生机制综述
Journal of Diabetes, Volume 15, Issue 4, Page 299-312, April 2023., 2023 Highlights With the increase in the elderly population, diabetic foot ulcers (DFUs) severely affect human health and societies worldwide. They will pose significant medical, social, and socioeconomic challenges. Reviewing the existing studies on the pathogenesis of DFUs, most of them focus on clinical nursing and treatment.
Haibo Deng +8 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 10, Page 695-710, October 2022., 2022 Highlights Electroacupuncture (EA) regulates the intestinal flora by promoting intestinal motility. EA regulated the intestinal flora to reduce the level of systemic inflammation. EA lowering the blood glucose by the IKKβ/NF‐κB‐JNK‐IRS‐1‐AKT signal pathway.
Jing An +7 more
wiley +1 more source
Glomerular cell cross talk in diabetic kidney diseases 糖尿病肾病中肾小球细胞间的相互作用
Journal of Diabetes, Volume 14, Issue 8, Page 514-523, August 2022., 2022 Highlights Glomerular cell cross talk is essential for maintaining the glomerular filtration barrier. In‐depth exploration of intraglomerular signaling pathway changes during diabetic kidney disease may help discover new therapeutic targets. Abstract Diabetic kidney disease (DKD) is a severe microvascular complication of diabetes mellitus.
Ruixue Dong, Youhua Xu
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 4, Page 247-260, April 2022., 2022 Highlights Phosphoinositide 3‐kinase (PI3K)/Akt signaling is an emerging promising therapeutic target for diabetes. Modulation of the PI3K/Akt signaling pathway, via protein and peptide‐based biologics, parasite‐derived molecules, plant extracts, or through microRNA interactions, will regulate the processes that determine the function of β‐cells and ...
Inah Camaya +2 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 3, Page 192-204, March 2022., 2022 Highlights Many proinflammatory cytokines could be decreased after 1 week of intensive insulin therapy using continuous subcutaneous insulin infusion (CSII). This was the first report showing that the cytokines of interleukin‐6 receptor (IL‐6R), tissue inhibitor of metalloproteinase‐2 (TIMP‐2), platelet‐derived growth factor type BB (PDGF‐BB), and ...
Junyu He +6 more
wiley +1 more source
Journal of Diabetes, Volume 14, Issue 1, Page 34-51, January 2022., 2022 Highlights Meta‐analysis of α‐ and β‐cell transcriptomes reveals modified energy metabolism, immune response, autophagy, and cellular stress pathways in cells from type 2 diabetes mellitus. The proportion of immature and senescent β‐cells is increased in islets from type 2 diabetes mellitus.
Emily Sara Marques +4 more
wiley +1 more source
Renoprotective effects of brown adipose tissue activation in diabetic mice 棕色脂肪激活对糖尿病小鼠的肾脏保护作用
Journal of Diabetes, Volume 11, Issue 12, Page 958-970, December 2019., 2019 Highlights This study demonstrates that of brown adipose tissue (BAT) with CL316,243 attenuates the progress of diabetic kidney disease (DKD). Mechanistically, the activation of BAT improved concentrations of circulating adipokines and microRNAs, which further affected the diabetic kidney and reactivated the AMP‐activated protein kinase/sirtuin 1 ...
Ying‐Ying Cai +10 more
wiley +1 more source
The Oncologist, Volume 24, Issue 12, Page e1437-e1442, December 2019., 2019 Abstract Testicular cancer is one of the few tumor types that have not yet benefited from targeted therapy. Still no new active agents for treating this cancer have been identified over the past 15 years. Once patients are refractory to cisplatin‐based chemotherapy, they will be expected to die from testicular cancer.
Bijun Lian +14 more
wiley +1 more source