Results 31 to 40 of about 26,684 (165)
吉林省地区朝鲜族和汉族健康人群LPL基因HindⅢ酶切位点多态性分布的研究
目的分析我国吉林省地区朝鲜族和汉族健康人群脂蛋白酯酶(lipoprotein lipase,LPL)基因HindⅢ酶切位点多态性的分布。方法应用聚合酶链反应(polimerase chain reaction,PCR)等技术检测66例朝鲜族和90例汉族LPL基因多态性,并将其基因型和等位基因在两族人群中的分布进行统计学分析。结果朝鲜族人群LPL基因P+P+基因型,P+P-基因型和P-P-基因型频率分别为57.58%,33.33%和9.09%;汉族人群分别为73.33%,24.44%和2.22 ...
安仙泉 +5 more
doaj
Learning Styles, Engagement and Anxiety in AI‐Mediated Writing: A Multimodal Feedback Study
ABSTRACT Artificial intelligence (AI) tools now permeate English academic writing. However, evidence on how feedback modalities align with student differences and with psychological mechanisms remains limited. Prior work often reduced learning styles to simple matches with delivery modes and treated learning engagement and writing anxiety as peripheral.
Yi Ren +3 more
wiley +1 more source
目的基于等位基因特异性PCR(allele-specific PCR,AS-PCR)原理,建立一种QPCR检测CLU基因与阿尔兹海默病(AD)相关性SNP位点基因型的筛选方法。方法根据CLU基因上的rs11136000,rs2279590和rs9331888 3个SNP位点设计特异性的野生型、突变型引物,使用实时荧光定量PCR(QPCR)对AD患者外周血样本进行SNP基因分型,以DNA基因测序法结果作为参考标准。结果 10例样本的QPCR定量分型结果显示 ...
李逸豪 +8 more
doaj
目的 研究院内MDRAB相关耐药基因及分子流行病学特征,为抗菌药物合理使用及医院感染控制提供依据。方法 对2019年2月至2019年10月间院内分离的15株MDRAB用多位点序列分型(MLST)鉴定菌株之间的亲缘关系,PCR法检测β-内酰胺类耐药基因、质粒介导的喹诺酮类耐药基因、氨基糖苷类耐药基因及消毒剂qacE△1基因。结果 MLST分析发现15株MDRAB有ST195(46.7%)、ST369(20%)、ST208(13.3%)、ST368(13.3%)和ST540(6.7%)5个序列类型 ...
姜梅杰 +4 more
doaj
Synthesizing Empirical Research on Learner Metacognition in Second Language Writing
ABSTRACT Despite considerable research interest in learner metacognition in second language (L2) writing, there is not yet a review that synthesizes the existing empirical findings and discusses their implications. To fill the void, this systematic review synthesized 39 empirical studies on learner metacognition in L2 writing and examined their salient
Chen Li, Icy Lee, Zhicheng Mao
wiley +1 more source
The effect of PNPLA3 ploymorphism in the intervention of non-alcoholic fatty liver disease [PDF]
研究目的 运动是治疗非酒精性脂肪性肝疾病的一个重要方法,而脂肪滋养蛋白基因(PNPLA3)是非酒精性脂肪性肝疾病的一个重要的基因遗传因子。本研究的目的是为了探讨脂肪滋养蛋白基因的多态性表达是否影响到运动干预非酒精性脂肪性肝疾病的过程。 研究方法 本研究共招募40-65岁中心性肥胖受试者1059人,进行常规体检,并运用彩超检测脂肪肝。并随机抽取476名肥胖受试者进行1H-MRS对其肝内甘油三酯进行定量测定。在这476名肥胖受试者中,随机抽取220人分为三组,强化运动组(先进行6个月的强化运动期 ...
黄竹锋
core
HHEX基因多态性与中国北方汉族人群精神分裂症及合并2型糖尿病发病的遗传学研究
目的探讨2型糖尿病易感基因HHEX与中国汉族人群2型糖尿病、精神分裂症以及精神分裂症合并2型糖尿病发病的关系。方法采用群体遗传学研究策略,以中国北方汉族人群331例精神分裂症患者、166例精神分裂症合并2型糖尿病患者、229例单纯2型糖尿病患者和389例健康对照个体为研究对象,采用TaqMan探针方法检测HHEX基因rs1111875位点基因型。结果拟合优度χ2检验分析显示rs1111875基因型频数分布在上述4个群体中均符合Hardy-Weinberg平衡定律(P>0.05 ...
赵晓霞 +7 more
doaj
ABSTRACT Many existing rubrics for L2 argumentative writing prioritize form‐based linguistic accuracy and complexity while insufficiently addressing substantive argumentative rigor and effectiveness. This limitation is further complicated by cross‐cultural variation in rhetorical conventions and educational practices, which challenge the direct ...
Zihan Xu, Peiyun Liu
wiley +1 more source
Gene structure analysis and differentially splicing between Plasmodium yoelii subspecies [PDF]
啮齿类动物约氏疟原虫(Plasmodiumyoelii)是研究宿主-寄生虫相互关系和疟原虫病理分子基础的一种重要的动物模型。尽管约氏疟原虫YM虫株的基本基因组信息已被测定,在最近也有许多啮齿类动物疟原虫的RNA-seq序列信息已见报道,但不同疟原虫品系或者亚种之间可能存在基因编码区及mRNA转录结构上的差异。构建多种疟原虫品系和亚种的cDNA文库将有助于我们对疟原虫遗传模式和转录组结构的认识。 本研究,我们用约氏疟原虫NSM虫株有或无MQ药物压力的红内期原虫样本构建了两个cDNA文库并对其进行深度测序 ...
刘建文
core
Application of Multiple Genetic Markers in Determination of Full and Half Sibling Relationship: A Case Report#br# [PDF]
Objective To investigate the application of the comprehensive use of multiple genetic markers in full and half sibling relationship testing through the identification of a case of suspected sibling relationship.
LIAO Yong, WU Feng, HOU Dong-lin,et al.
core +1 more source

