Results 51 to 60 of about 1,683,242 (173)
, 2008 利用基因表达谱数据进行肿瘤亚型分类,对于癌症研究有着非常重要的意义。由于基因表达数据的维数很高,必须从大量基因中选取一些特征基因用于分类,才能取得好的效果。但以往方法所提取的特征基因,彼此之间存在较高的相关性。本文提出了一种基于高维向量分析的特征基因提取方法:首先利用基因与理想基因间相似度作为评价准则得到候选集,然后去除候选集中相关性强的冗余基因。用此方法选出的特征基因是与分类相关但彼此无关的 ...
王守觉, 周凌飞
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Rare Metals, Volume 45, Issue 11, November 2026.ABSTRACT Osteoarthritis (OA) therapy remains constrained by the coexistence of irreversible cartilage loss and a persistently hostile joint microenvironment characterized by oxidative stress, synovial inflammation, and impaired tissue‐regenerative signaling.
Xinyu Wu +11 more
wiley +1 more source
GHK‐Cu Delays Aging Through the Repair of Mitochondrial Dysfunction
Rare Metals, Volume 45, Issue 11, November 2026.ABSTRACT Althugh glycyl‐L‐histidyl‐L‐lysine copper (GHK‐Cu) shows antiaging potential, its precise molecular mechanisms remain unclear. Using Caenorhabditis elegans (C. elegans) as an in vivo aging model, we observed that GHK‐Cu extended organismal lifespan and improved stress resilience.
Haoquan Yu +8 more
wiley +1 more source
World Food Policy, Volume 12, Issue 2, November 2026.ABSTRACT This study explores environmental justice issues in coastal food systems, focusing on conflicts between small‐scale fisheries and the energy sector due to differing goals in managing food and energy sources. It does so by examining the interdependence between institutions, policies, and different types of knowledge; key elements in building ...
Mateus Henrique Amaral +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2019 目的基于等位基因特异性PCR(allele-specific PCR,AS-PCR)原理,建立一种QPCR检测CLU基因与阿尔兹海默病(AD)相关性SNP位点基因型的筛选方法。方法根据CLU基因上的rs11136000,rs2279590和rs9331888 3个SNP位点设计特异性的野生型、突变型引物,使用实时荧光定量PCR(QPCR)对AD患者外周血样本进行SNP基因分型,以DNA基因测序法结果作为参考标准。结果 10例样本的QPCR定量分型结果显示 ...
李逸豪 +8 more
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World Water Policy, Volume 12, Issue 4, November 2026.ABSTRACT Biochemical oxygen demand (BOD) remains a core indicator of organic pollution in freshwater monitoring, but its role in water policy and practice is changing as water‐quality assessment moves toward predictive, integrative, and decision‐support approaches.
Isadora Favero Roque Cenci +5 more
wiley +1 more source
, 2009 以生长于田间的玉米掖单13(耐旱基因型玉米)和丹玉13(不耐旱基因型玉米)为试验材料,应用ICP对供试玉米的初生根和第一、二、三、四、五、六、七、八和第九层次生根的大量元素氮、磷、钾、钙和镁等项指标进行了测定和比较分析。结果表明:除个别根外,耐旱基因型玉米不同类型根中的全氮含量和速效氮含量极显著低于不耐旱基因型玉米根系(P0 ...
宋凤斌, 刘胜群, 王晓波
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过氧化物酶增生物-激活受体γ2基因多态性与2型糖尿病的相关性
Zhongguo shiyan zhenduanxue, 2010 目的探讨PPARγ2基因多态性与2型糖尿病的关系。方法以rs1875796为遗传标记,应用多聚酶链-限制性片段长度多态性（PCR-RFLP）技术检测250例2型糖尿病患者和337例健康对照人群PPARγ2基因型。结果 Rs1875796基因型频率CC:CT:TT在2型糖尿病和正常对照组的频率分布分别为2.8%:27.2%:70.0%和2.7%:25.5%:71.8%;C等位基因和T等位基因在2型糖尿病组和正常对照组的频率分布分别为16.4%:83.6%和15.4%:84.6%,两组间的等位基因 ...
高鹏, 吴江, 杜丹华, 张颖
doaj
World Water Policy, Volume 12, Issue 4, November 2026.ABSTRACT This paper describes and analyzes recharge practices in Bács‐Kiskun County, Hungary, within what can be categorized as the farmer domain. Such locally embedded aquifer recharge practices remain underexplored in Hungary. Current research and funding largely focus on large‐scale Managed Aquifer Recharge (MAR) interventions emphasizing intended ...
Helen Sundberg, Michael Gilek
wiley +1 more source
东北汉族人群抵抗素基因rs1862513（G/C）多态性与2型糖尿病相关性研究
Zhongguo shiyan zhenduanxue, 2017 目的探讨东北汉族抵抗素基因rs1862513（G/C）位点与2型糖尿病发病及临床表型相关性。方法应用连接酶反应分型法检测79例2型糖尿病患者及79例正常对照者rs1862513（G/C）多态性。结果 2型糖尿病组和对照组抵抗素rs1862513（G/C）位点基因型分布分别为GG49.5%、GC44.3%、CC6.2%和GG40.2%、GC47.4%、CC12.4%;等位基因频率分别为G型71.6%、C 28.4%和G型63.9%、C型36.1%,该位点的基因型分布和等位基因频率在两组间分布均无统计学意义（
陈珍珍 +4 more
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