Results 51 to 60 of about 36,876 (177)

转化生长因子β1基因多态性与食管癌的关系

open access: yesZhongguo shiyan zhenduanxue, 2010
目的研究转化生长因子β1(TGF-β1)基因启动子区-800G/A和第1外显子+915G/C基因多态性各等位基因及基因型在食管癌患者中的分布频率,初步分析其基因型及血清水平与食管癌的相关性。方法采用序列特异性引物聚合酶链反应(PCR-SSP)和聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术,检测118例食管癌患者和130例正常对照组TGF-β1的基因多态性,包括TGF-β1基因启动子-800G/A、第1外显子+915G/C位点,同时采用酶联免疫吸附试验(ELISA)检测血清TGF-β1水平 ...
唐任光   +5 more
doaj  

Exploring English Language Learners’ Vocabulary Knowledge and Usage When Speaking

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT Vocabulary forms a fundamental component of speaking ability, as it enables speakers to convey meaning accurately, fluently, and effectively. Although the relationship between vocabulary and speaking has been investigated to some extent, gaps remain in understanding the link between learners’ vocabulary knowledge and their speaking proficiency,
Junyan Guo, Martin East
wiley   +1 more source

“It Can't be Translated Into a Conventional English Phrase”: Crafting Academic Identities Through Translingual Writing

open access: yesInternational Journal of Applied Linguistics, EarlyView.
ABSTRACT This qualitative multiple case study explores multilingual postgraduate students’ academic identities through writing at an EMI university in Hong Kong, with a focus on how they gain legitimacy in knowledge‑making with their multilingual repertoires. Grounded in a poststructuralist understanding of identities as fluid and negotiated, the study
Siqi Song, Ken Lau
wiley   +1 more source

Predictive evolutionary genomics: principles, validation, and practice

open access: yesNew Phytologist, EarlyView.
Summary Climate change and habitat loss are driving rapid evolutionary responses in populations world‐wide, which creates an urgent need for evolutionary forecasting in conservation and agriculture. Such forecasting can be categorized into three time scales: trait‐based models that use multivariate quantitative genetic equations to project correlated ...
Daniel Ortiz‐Barrientos   +5 more
wiley   +1 more source

颅内动脉瘤信号传导相关基因的筛选

open access: yesZhongshan Daxue xuebao. Yixue kexue ban, 2007
【目的】基因芯片技术建立颅内动脉瘤患者血液单核细胞基因表达谱,筛选与信号传导相关的基因表达情况。【方法】50例颅内动脉瘤患者外周血,10例正常成人作为对照组,分离血液单核细胞,提取总RNA,与含22215个人类基因的Affymetrix寡核苷酸基因芯片杂交、洗脱、染色和扫描,分析检测的数据。荧光定量RT-PCR验证芯片结果。【结果】检测的22215个基因中,颅内动脉瘤共差异表达的基因有325个,差异水平均达2倍以上的基因有35个,生物信息学分析发现信号传导相关基因有7个,其中上调基因5个,下调基因2个。【
石忠松   +6 more
doaj  

AI foundation models in plant biology

open access: yesNew Phytologist, EarlyView.
Foundation models decode genomes, engineer proteins, phenotype crops, and drive AI agents across plant biology. This figure was created in BioRender (BioRender.com/xcmmkel). Summary Rapid technological progress has enabled plant biologists to accumulate unprecedented volumes of multi‐scale, multi‐modal data, yet this abundance of data has intensified ...
Haopeng Yu
wiley   +1 more source

壳聚糖纳米粒子基因载体的制备与相关研究

open access: yesZhongguo shiyan zhenduanxue, 2013
目的制备CS/pcDNA3.1/GDNF混悬液,并对壳聚糖作为基因载体的相关性能进行检测。方法采用复凝聚法制备CS/pcDNA3.1/GDNF混悬液,观察壳聚糖纳米粒子的物理性能,稳定性,基因结合效率,基因保护功能,缓慢释放效果及基因负载力和负载率。结果壳聚糖大小为106-228nm,性质稳定,具有良好的基因携带功能,能够有效地保护所携带基因,基因负载力及基因负载率较高。结论应用复凝聚法制得壳聚糖纳米粒子,能够满足基因载体的需要,是一个较理想的基因载体。
李世龙, 邵国喜, 刘钦毅, 周贺
doaj  

Neutral interactions among non‐native plants are common

open access: yesNew Phytologist, EarlyView.
Global distribution of studies and overall effect of co‐invasion for all metrics of non‐native plant performance combined. Summary Globalization has accelerated the establishment of non‐native plant species, increasing the prevalence of multispecies co‐invasions; yet interactions among co‐invaders remain poorly understood.
Feng He   +7 more
wiley   +1 more source

Navigating the Algorithmic State: Public Values and Citizens' Preferences of AI‐Driven Public Service Delivery

open access: yesPublic Administration, EarlyView.
ABSTRACT As the public sector increasingly adopts AI‐powered automated decision systems (ADS), understanding how citizens experience and value ADS use in public decision‐making is both normatively and practically important. Therefore, we examine and compare the effects of seven attributes of public values on citizens' support for ADS adoption in two ...
Guimin Zheng   +4 more
wiley   +1 more source

吉林省地区朝鲜族和汉族健康人群LPL基因HindⅢ酶切位点多态性分布的研究

open access: yesZhongguo shiyan zhenduanxue, 2010
目的分析我国吉林省地区朝鲜族和汉族健康人群脂蛋白酯酶(lipoprotein lipase,LPL)基因HindⅢ酶切位点多态性的分布。方法应用聚合酶链反应(polimerase chain reaction,PCR)等技术检测66例朝鲜族和90例汉族LPL基因多态性,并将其基因型和等位基因在两族人群中的分布进行统计学分析。结果朝鲜族人群LPL基因P+P+基因型,P+P-基因型和P-P-基因型频率分别为57.58%,33.33%和9.09%;汉族人群分别为73.33%,24.44%和2.22 ...
安仙泉   +5 more
doaj  

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