Results 11 to 20 of about 6,005 (169)
Abstract Background Diabetic foot infection, particularly osteomyelitis, is a major risk factor of amputation in persons with diabetes. Bone biopsy with microbial examination is considered the gold standard of diagnosis of osteomyelitis, providing information about the offending pathogens as well as their antibiotics susceptibility.
Hassan Al‐Balas +3 more
wiley +1 more source
The nose is not enough: Multi‐site sampling is best for MRSP detection in dogs and households
Abstract Background Following recovery from meticillin‐resistant Staphylococcus pseudintermedius (MRSP) infection of any type, dogs may continue to carry MRSP asymptomatically on skin and mucosae, contributing to the spread of this multidrug‐resistant, veterinary hospital‐associated pathogen with zoonotic potential to others and into the environment ...
Sian‐Marie Frosini +3 more
wiley +1 more source
Highlights To what extent NAFLD is associated with glycemic remission among the general population remains unclear. The study elaborated that presence of NAFLD and fibrosis status decreased the chance of glycemic remission whereas NAFLD improvement mitigated glycemic deterioration, emphasizing joint management to liver‐focused subgroups of diabetes ...
Zhuojun Xin +15 more
wiley +1 more source
Highlights Insulin degludec/liraglutide (IDegLira) has good efficacy and tolerability in Chinese adults with type 2 diabetes not controlled on oral antidiabetic drugs. IDegLira provides the clinical advantages of insulin and glucagon‐like peptide 1 receptor agonists, improving glycemic control while reducing the main adverse effects of insulin (weight ...
Weiqing Wang +11 more
wiley +1 more source
Background – Because of the increased incidence of multidrug‐resistant (MDR) bacteria, the use of disinfectants over antibiotics has been encouraged. However, the interactions between disinfectants and host local immunity are poorly understood. Objective – To assess the effects of chlorhexidine digluconate (Chx), with and without selected host defence ...
Domenico Santoro +3 more
wiley +1 more source
Background – Canine atopic dermatitis (cAD) is a common chronic relapsing pruritic skin disease for which management commonly relies on life‐long use of immunomodulatory drugs. A number of the medications used are associated with adverse effects and the potential for complications during long‐term use.
Adrian Watson +3 more
wiley +1 more source
Background Antimicrobial resistance in Staphylococcus pseudintermedius (SP) and the prevalence of meticillin‐resistant SP (MRSP) is increasing in dogs worldwide. Objectives To evaluate the influence of hospital size on antimicrobial resistance of SP and whether restricted use of antimicrobials based on antibiograms could reduce the identification of ...
Keita Iyori +5 more
wiley +1 more source
Background Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about micro‐organisms. Hypothesis/Objectives Oxford Nanopore technology enables quality sequencing and de novo assembly of the whole genome of S.
Lluís Ferrer +13 more
wiley +1 more source
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling +9 more
wiley +1 more source

