Results 11 to 20 of about 6,978 (169)

Is fluoroscopy‐guided percutaneous bone biopsy of diabetic foot with suspected osteomyelitis worthwhile? A retrospective study 一项回顾性研究:怀疑骨髓炎的糖尿病足在透视引导下经皮骨活检是否具有价值?

Journal of Diabetes, Volume 15, Issue 4, Page 332-337, April 2023., 2023
Abstract Background Diabetic foot infection, particularly osteomyelitis, is a major risk factor of amputation in persons with diabetes. Bone biopsy with microbial examination is considered the gold standard of diagnosis of osteomyelitis, providing information about the offending pathogens as well as their antibiotics susceptibility.
Hassan Al‐Balas, Zeyad A. Metwalli, Aaditya Nagaraj, David M. Sada   +3 more
wiley   +1 more source

The nose is not enough: Multi‐site sampling is best for MRSP detection in dogs and households

Veterinary Dermatology, Volume 33, Issue 6, Page 576-580, December 2022., 2022
Abstract Background Following recovery from meticillin‐resistant Staphylococcus pseudintermedius (MRSP) infection of any type, dogs may continue to carry MRSP asymptomatically on skin and mucosae, contributing to the spread of this multidrug‐resistant, veterinary hospital‐associated pathogen with zoonotic potential to others and into the environment ...
Sian‐Marie Frosini, Ross Bond, Ruth H. King, Anette Loeffler   +3 more
wiley   +1 more source

Nonalcoholic fatty liver disease in relation to the remission and progression along the glycemic continuum 非酒精性脂肪性肝病与血糖的缓解和进展

Journal of Diabetes, Volume 14, Issue 9, Page 606-619, September 2022., 2022
Highlights To what extent NAFLD is associated with glycemic remission among the general population remains unclear. The study elaborated that presence of NAFLD and fibrosis status decreased the chance of glycemic remission whereas NAFLD improvement mitigated glycemic deterioration, emphasizing joint management to liver‐focused subgroups of diabetes ...
Zhuojun Xin, Jiaojiao Huang, Qiuyu Cao, Jialu Wang, Ruixin He, Tianzhichao Hou, Yi Ding, Jieli Lu, Min Xu, Tiange Wang, Zhiyun Zhao, Weiqing Wang, Guang Ning, Yufang Bi, Yu Xu, Mian Li   +15 more
wiley   +1 more source

DUAL I China: Improved glycemic control with IDegLira versus its individual components in a randomized trial with Chinese participants with type 2 diabetes uncontrolled on oral antidiabetic drugs DUAL I China:在一项对未服用口服降糖药物的中国2型糖尿病患者进行的随机试验中, IDegLira与其单独成分相比改善了血糖控制

Journal of Diabetes, Volume 14, Issue 6, Page 401-413, June 2022., 2022
Highlights Insulin degludec/liraglutide (IDegLira) has good efficacy and tolerability in Chinese adults with type 2 diabetes not controlled on oral antidiabetic drugs. IDegLira provides the clinical advantages of insulin and glucagon‐like peptide 1 receptor agonists, improving glycemic control while reducing the main adverse effects of insulin (weight ...
Weiqing Wang, Bue F. Ross Agner, Bin Luo, Lei Liu, Ming Liu, Yongde Peng, Shen Qu, Karolina Amelia Stachlewska, Guixia Wang, Guoyue Yuan, Qiu Zhang, Guang Ning   +11 more
wiley   +1 more source

Evaluation of the effects of chlorhexidine digluconate with and without cBD103 or cCath against multidrug‐resistant clinical isolates of Staphylococcus pseudintermedius

Veterinary Dermatology, Volume 33, Issue 1, Page 17-e6, February 2022., 2022
Background – Because of the increased incidence of multidrug‐resistant (MDR) bacteria, the use of disinfectants over antibiotics has been encouraged. However, the interactions between disinfectants and host local immunity are poorly understood. Objective – To assess the effects of chlorhexidine digluconate (Chx), with and without selected host defence ...
Domenico Santoro, Lopamudra Kher, Vanessa Chala, Christelle Navarro   +3 more
wiley   +1 more source

A novel therapeutic diet can significantly reduce the medication score and pruritus of dogs with atopic dermatitis during a nine‐month controlled study

Veterinary Dermatology, Volume 33, Issue 1, Page 55-e18, February 2022., 2022
Background – Canine atopic dermatitis (cAD) is a common chronic relapsing pruritic skin disease for which management commonly relies on life‐long use of immunomodulatory drugs. A number of the medications used are associated with adverse effects and the potential for complications during long‐term use.
Adrian Watson, Ana Rostaher, Nina M Fischer, Claude Favrot   +3 more
wiley   +1 more source

Influence of hospital size on antimicrobial resistance and advantages of restricting antimicrobial use based on cumulative antibiograms in dogs with Staphylococcus pseudintermedius infections in Japan

Veterinary Dermatology, Volume 32, Issue 6, Page 668-e178, December 2021., 2021
Background Antimicrobial resistance in Staphylococcus pseudintermedius (SP) and the prevalence of meticillin‐resistant SP (MRSP) is increasing in dogs worldwide. Objectives To evaluate the influence of hospital size on antimicrobial resistance of SP and whether restricted use of antimicrobials based on antibiograms could reduce the identification of ...
Keita Iyori, Taku Shishikura, Kenta Shimoike, Kenichi Minoshima, Ichiro Imanishi, Yoichi Toyoda   +5 more
wiley   +1 more source

Whole genome sequencing and de novo assembly of Staphylococcus pseudintermedius: a pangenome approach to unravelling pathogenesis of canine pyoderma

Veterinary Dermatology, Volume 32, Issue 6, Page 654-663, December 2021., 2021
Background Staphylococcus pseudintermedius is the main aetiological agent of canine pyoderma. Whole genome sequencing is the most comprehensive way of obtaining relevant genomic information about micro‐organisms. Hypothesis/Objectives Oxford Nanopore technology enables quality sequencing and de novo assembly of the whole genome of S.
Lluís Ferrer, Rocío García‐Fonticoba, Daniel Pérez, Joaquim Viñes, Norma Fàbregas, Sergi Madroñero, Gabriele Meroni, Piera A. Martino, Sofía Martínez, M. Laura Maté, Sergio Sánchez‐Bruni, Anna Cuscó, Lourdes Migura‐García, Olga Francino   +13 more
wiley   +1 more source

Nanodrug delivery in reversing multidrug resistance in breast cancer cells [PDF]

, 2016
乳腺癌细胞产生多药耐药（Multidrugresistance，MDR）是乳腺癌化疗失败最主要的原因之一，深入研究拮抗或逆转乳腺癌多药耐药有着重要的理论和临床意义。紫杉醇（Paclitaxel，PTX)是目前临床上广泛应用的广谱抗癌药物。临床广泛使用的紫杉醇制剂（商品名“泰素”）毒副反应严重，超敏反应强烈，无明显靶向性，可诱发多药耐药，因此紫杉醇新制剂研究是当前国际国内的热点问题。 本文旨在研制出具有良好临床适应性、可逆转肿瘤多药耐药的紫杉醇纳米制剂，并使其具有磁靶向和光动力治疗的多重功能。首先 ...
王颖君
core  

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

Rare Metals, Volume 45, Issue 2, February 2026.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan, Shengjie Xue, Junyi Yin, Shaolei Wang, Yunlei Zhou, Jieyue Liao   +5 more
wiley   +1 more source