[CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway]. [PDF]
Sichuan Da Xue Xue Bao Yi Xue BanWang J +5 more
europepmc +1 more source
, 2013 (7)降低耐药性的对策①病原菌产生耐药性的原因耐药性又称抗药性。耐药性是病原菌适应环境和化学药物作用的结果,可分为先天和后天耐药性2种。先天性耐药性是遗传学个体差异和种群差异的表现,同一种病原菌对不同药物的敏感性差异及同一群体中的某些个体对一种药物的敏感性差异均与先天耐药性有关 ...
汪建国
core
[Eculizumab resistance caused by C5 gene polymorphism in a patient with paroxysmal nocturnal hemoglobinuria: a case report]. [PDF]
Zhonghua Xue Ye Xue Za ZhiZhou RQ +5 more
europepmc +1 more source
[Advances in the diagnosis and treatment of patients with multidrug-resistant bacterial infections combined with severe liver disease]. [PDF]
Zhonghua Gan Zang Bing Za ZhiLu XL +5 more
europepmc +1 more source
[Rapid detection of fluconazole resistance in <i>Candida tropicalis</i> using MALDI-TOF mass spectrometry]. [PDF]
Nan Fang Yi Ke Da Xue Xue BaoHou J +5 more
europepmc +1 more source
, 2008 本发明涉及碳纳米管作为载体在抗癌药物转运中的应用。本发明中合成的氧化碳纳米管可以键合上不同的抗癌药物，键合后的药物分子可以透过细胞膜并在细胞中分布而不会被排出。实验结果表明，没有键合碳纳米管的药物分子在多药耐药细胞系和其母细胞系中的分布差异很大，而在键合之后其分布差异显著减小，这说明多药耐药细胞系上高表达的渗透性糖蛋白没有将键合在碳纳米管上的药物分子大量泵出细胞外，碳纳米管有效地抑制了渗透性糖蛋白外排的作用，从而证明碳纳米管可以作为载体并应用于抗癌药物转运中，这为研制新型的抗癌药物提供了新的思路 ...
孔 亮, 肖 华, 邹汉法
core
[Advances in single cell omics applications in mantle cell lymphoma]. [PDF]
Zhonghua Xue Ye Xue Za ZhiWang C, Zhang Q, Cao X.
europepmc +1 more source
, 1995 中成药在临床多应用于常见病和多发病,具有疗效好、服用方便、便于携带、便于保存的优点。但要充分发挥药效,又不产生毒副作用,应遵循,①根据疾病性质选择不同剂型;②根据不同剂型的特性选择药物;③便于患者服用;④中成药与西药应合理配用 ...
陈谦信, 韩秀珍
core
[A transition from targeting immune evasion to a multidisciplinary collaborative treatment framework for "homotherapy for heteropathy" in liver metastases]. [PDF]
Zhonghua Gan Zang Bing Za ZhiZhang Q, Zhang N, Lu YY.
europepmc +1 more source
[Multidrug resistant organisms in burn intensive care unit: strategies and opinions]. [PDF]
Zhonghua Shao Shang Za Zhi, 2021 Yuan ZQ, Peng YZ.
europepmc +1 more source