Results 11 to 20 of about 570 (115)
Research Progresses of Tri-Allelic Patterns in Autosomal STR in Forensic DNA Analysis [PDF]
, 2023 Tri-allelic pattern in autosomal STR is a common abnormal typing phenomenon in forensic DNA analysis, which brings difficulties and uncertainties to the evaluation of the evidence weight in actual cases. This paper reviews the types, formation mechanism,
Xiao-yan MA, Hong-yu SUN, Qing LI
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Zhongshan Daxue xuebao. Yixue kexue ban, 2015 摘 要: 【目的】 采用多重置换扩增建立一种可靠?准确的植入前遗传学诊断方法,可应用于软骨发育不全的植入前遗传学诊断?【方法】 对软骨发育不全高危家系采用8个与成纤维细胞生长因子受体3(FGFR3)基因紧密连锁的短串联重复序列(STR)进行软骨发育与不全(ACH)的单体型分析?采用多重置换扩增(MDA)对单细胞进行全基因组扩增,对其产物采用在家系分析中具有多态性的STR位点及PCR-限制性酶切法检测FGFR3基因进行分析?【结果】 对家系分析中,共有5个STR位点具有多态性 ...
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Calculation of the Paternity Index for the Alleged Father Related to the Child’s Mother [PDF]
, 2023 Objective To derive the paternity index （PI） calculation formula of the alleged father （AF） when the AF is a relative （parent/child， siblings， grandparent/grandchild， uncle/nephew， first cousins） of the child’s biological mother.
Yu-ting WANG, Qiang ZHU, Yu-han HU, Yi-fan WEI, Ting-yun HOU, Ji ZHANG
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CiteSpace-based Document Information Visualization of Literature Published by Journal of Forensic Medicine from 1985 to 2018 [PDF]
, 2019 Objective To analyze a knowledge web of the literature published by Journal of Forensic Medicine from its founding in 1985 to 2018, describe the evolving process of forensic science research and explore the research hotspots and frontiers at present ...
XIE Xiao-ping, PAN Zhen-jie, WANG Kang,et al
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Evaluation of Detection Efficiency for Trio Full Sibling Testing [PDF]
, 2023 Objective To study the detection efficiency of trio full sibling with another known full sibling reference added under different number of autosomal STR typing systems. Methods Based on 43 detection systems consisting of 13 to 55 representative autosomal
Hui CHEN, Ran LI, Yu ZANG, Jing-yi YANG, Ri-ga WU, Hong-yu SUN
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Forensic Application of SiFaSTRTM 23plex DNA ID System in Han Population of Eastern China [PDF]
, 2018 Objective To investigate the genetic polymorphism of 21 autosomal STR loci and DYS391 locus of SiFaSTRTM 23plex DNA ID system in Han population of eastern China and to evaluate its application value in forensic science.
BAO Yun, SHENG Xiang, ZHANG Jia-shuo，et al
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, 2018 性染色体数目异常疾病是一类严重困扰人类生活的综合征,患者多能生存,但常有性腺发育不全、多发畸形、不育等异常表现。该病无法治愈,经激素替代治疗等干预措施可有效缓解症状,但早期确诊严重依赖于相关临床诊断技术的发展。该文拟就现今常见检测性染色体数目异常技术的发展作一综述,比较各技术优缺点及评价其在临床诊断中的应用价值,以方便检验工作者科学合理地采用相关技术,为临床提供更为准确可靠的实验室依据,推进对该类疾病的诊治与研究。国家自然科学基金面上项目(81572084);;厦门市科技重大专项 ...
周裕林, 郑欣怡
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Identification Strategy of Biological Half Sibling Relationship [PDF]
, 2023 Objective To compare the application value of the likelihood ratio （LR） method and identity by state （IBS） method in the identification involving half sibling relationships， and to provide a reference for the setting of relevant standards for ...
Zheng TAN, Guan-ju MA, Li-hong FU, Xiao-jing ZHANG, Qian WANG, Guang-ping FU, Qing-qing DU, Shu-jin LI
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Application of RapidHITTM 200 System in Forensic Medicine [PDF]
, 2018 Objective To validate the analysis capability of RapidHITTM 200 system for four kinds of routine forensic samples and the recyclable capability of template, template DNA and PCR products in the process of twice duplicate detection.
SUN Shuai, TIAN Yu-miao, TANG Ji-ming，et al
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Application of Familial Y-STR Haplotype Mismatch Tolerance in Genealogy Inference [PDF]
, 2023 Objective To provide a guideline for genealogy inference and family lineage investigation through a study of the mismatch tolerance distribution of Y-STR loci in Chinese Han male lineage.
Meng-jie TONG, Ke ZHANG, Cai-xia LI, Guang-feng ZHANG, Wen-jie ZHANG, Lan YANG, Qing-tang HOU, Jing LIU
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