Engineering Ferritin Nanoparticles for Theranostic Probes Development [PDF]
, 2016 疾病的诊断治疗学在近年来得到了巨大关注和广泛研究，以蛋白质为基础的纳米材料具有优异生物相容性、生物降解性、灵活的可修饰性等特点，在癌症的诊疗一体化研究上发挥着巨大作用。鉴于发展以蛋白质为核心的新型诊疗一体化探针具有重要的可应用和临床转化意义，我们在本论文中研究设计了多种以铁蛋白为核心的纳米材料，并着重探究了各种材料在诊疗一体化中的应用。主要内容概括如下： 第一章，我们简要介绍了肿瘤诊断治疗技术的发展和现状，着重探讨了肿瘤诊断治疗一体化的研究现状 ...
王占通
core
Powerful representation of the poor? German welfare associations' narrative advocacy during COVID‐19
Policy Studies Journal, EarlyView.Abstract The COVID‐19 pandemic sparked unprecedented experimentation in the German social assistance system, leading to changes previously considered impracticable by policymakers. This included a sanctions moratorium, easier access to benefits, and temporary cash transfers, all of which were advocated by welfare associations—key organized interests ...
Christopher Smith Ochoa
wiley +1 more source
Physiological analysis on long shelf-life in ripening mutants (rin, nor, alc) tomato and their F1 [PDF]
, 1993 English abstract: Changes in respiration, ethylene production, PG activity and firmness during ripening period were monitored in fruits of the 'alcobaca', 'nor', 'rin' mutants and those of normal tomato (Lycopersicon esculentum Mill.) In fruits of ...
Lu, C, Xu, H, Zhao, Y
core
Veterinary Dermatology, EarlyView.ABSTRACT Background Canine atopic dermatitis (cAD) is a multifactorial, inherited skin disease, estimated to affect ≤ 15% of dogs. Studies of skin messenger mRNA in cAD currently use invasive methods, including blood sampling and biopsy collection, whilst advances in human atopic dermatitis study methodology have demonstrated reliable use of minimally ...
Xavier Langon +5 more
wiley +1 more source
Functional analysis of Hedgehog gene in amphioxus embryogenesis and mutants construction related to the Hedgehog signaling pathway [PDF]
, 2015 Hedgehog（Hh）基因在动物胚胎发育过程中有着重要的作用，该基因最早在果蝇中发现，参与果蝇分节极性（segmentpolarity）的形成及翅原基前后组织中心的建立；在海胆中，参与中胚层的分化；而在脊椎动物中，该基因主要参与中枢神经系统（CNS）、轴旁中胚层及附肢的发育。在头索动物文昌鱼中，前人基于Hh的表达谱分析，推测该基因参与神经管的发育及左右轴的建立，提出Hh对神经管腹侧神经元分化的作用可能是一原始特征。 本文用基因敲低、过表达和敲除3种方法对文昌鱼Hh基因在胚胎发育中的功能做了进一步研究 ...
王慧
core
ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis
Veterinary Dermatology, EarlyView.ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake +2 more
wiley +1 more source
Genetic analysis and gene mapping of panicle branches stay-green trait in rice [PDF]
, 2016 水稻是重要的粮食作物之一，全球一半以上的人口以大米为主食。随着世界人口的增长，人们正面临着越来越严重的粮食危机。如何增加水稻产量一直是作物育种以及植物学研究的重要目标。近年来水稻遗传育种工作者发现了一些成熟期叶片的叶绿素不降解或仅少量降解而使叶片仍保持绿色的持绿型水稻品种，研究发现其叶片持绿性状多数属多基因控制的数量遗传，少数属隐性主效基因控制的质量性状遗传，相关基因大多已被鉴定及克隆。迄今为止，尚未见穗枝梗持绿性状的研究报道。佳辐占系本课题组育成的优质高产早稻品种，已在生产上大面积推广应用 ...
王永杰
core
Political Trust and Aspirations to Influence Social Media During a Crisis: A Longitudinal Study
Policy &Internet, Volume 18, Issue 1, March 2026.ABSTRACT This study investigated how political trust shaped citizens' aspirations to influence others on social media during a COVID‐19 pandemic. Using four‐wave longitudinal survey data (2017–2021; N = 2172) collected from 543 citizens in Finland, we first analysed how political trust moderated the temporal development of individuals' aspirations to ...
Aki Koivula +2 more
wiley +1 more source
Devouring the Invaders: The Racial‐Ecological Politics of the Chinese Crayfish Trade in Kenya
American Anthropologist, Volume 128, Issue 1, Page 183-194, March 2026.ABSTRACT This article examines entanglements of ecology, race, and foodways at Lake Naivasha in Kenya. Nonnative Louisiana red swamp crayfish (Procambarus clarkii), first introduced to Kenya in the 1960s, were once viewed as invasive but are now sought after as a delicacy among Kenya's Chinese community.
Amanda Kaminsky
wiley +1 more source
The Impact of Smoking Status on the Efficacy of Erlotinib in Patients with Advanced Non-small Cell Lung Cancer [PDF]
, 2009 Background and objective Erlotinib is a targeted treatment for advanced non-small cell lung cancer. Smoking status may be one of influencing factors of the efficacy of erlotinib.
Jinji YANG +5 more
core