Results 21 to 30 of about 11,234 (189)
Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan +5 more
wiley +1 more source
Advances in Elemene Nanodelivery Systems: From Material Design to Disease Treatment
ABSTRACT Elemene (ELE) is a bioactive sesquiterpenoid extracted from traditional Chinese herbs, demonstrating broad‐spectrum antitumor, anti‐inflammatory, and analgesic properties with significant therapeutic potential. However, its clinical utility is constrained by inherent physicochemical limitations, including volatility and hydrophobicity, which ...
Xiao Wang +9 more
wiley +1 more source
Recent Progress in the Development of Metal‐Based Radiosensitizations for Cancer Therapy: A Review
ABSTRACT Radiotherapy (RT) remains an indispensable means in cancer treatment; however, its therapeutic efficacy is often limited by tumor radioresistance and side effect of damage to healthy tissue. The advances in nanotechnology have propelled metal radiosensitizers to forefront of precision medicine.
Xiao‐Xia Wu +12 more
wiley +1 more source
异位性皮炎(AD, 通常也称为湿疹)是儿童时期最常见的皮肤病之一, 英国和爱尔兰多达 1/4 的儿童受其影响。AD 患者经常在其皮肤上携带金黄色葡萄球菌。当患有 AD 的个体出现爆发时,即皮肤发红和瘙痒增加,皮肤上通常会有更多的金黄色葡萄球菌。因此通常用抗生素治疗 AD。这项研究在爱尔兰都柏林和英国圣安德鲁斯进行,旨在了解与未患 AD 的儿童相比, AD 患儿的金黄色葡萄球菌的抗生素耐药性(意味着细菌能够抵抗杀死它们的抗生素)的差异。从 50 名在皮肤病诊所就诊的患有 AD 的儿童中收集皮肤拭子 ...
C. Harkins +12 more
semanticscholar +1 more source
ABSTRACT The escalating issue of drug‐resistant pathogens, largely driven by the overuse of conventional antibiotics, has become a significant global health threat. Developing alternative therapeutic strategies and fabricating natural biological enzyme materials that mimic the high efficiency, selectivity, and mild‐operating conditions of natural ...
Shuai He +11 more
wiley +1 more source
The optimized expression technology of marine animal-sourced antimicrobial peptides in Pichia pastoris and the development of antimicrobial peptide as feedstuff additive [PDF]
抗生素污染问题是目前影响我国水产养殖业可持续健康发展的重大科技问题,抗生素(antibiotics)作为常用抗菌药物,被广泛应用于水产养殖业,但是抗生素超标所引起的细菌耐药性问题已成为全球公共健康问题,因此寻找抗生素的有效替代品是目前国内外本领域的研究热点之一。抗菌肽(antimicrobialpeptide)是先天性免疫的重要组分,广泛存在于生物界的各个门类,进化上相对保守,具有广谱抗菌活性、且不会产生细菌耐药性,被预言为最有希望替代抗生素的天然药物,具有广阔的应用前景 ...
彭会
core
To Ban or Not to Ban: The UK's Hamlet Moment With Farm Antibiotics
ABSTRACT This article applies the Multiple Streams Framework (MSF) to examine post‐Brexit antimicrobial resistance (AMR) governance in UK agriculture, focusing on the contested regulation of prophylactic antibiotic use in farm animals. The study reveals how Brexit created a structural policy window, yet political and ideological dynamics rendered it ...
George Asiamah
wiley +1 more source
貉源致病性肺炎克雷伯氏菌对喹诺酮类药物耐药表型及耐药基因检测
为了检测貉源致病性肺炎克雷伯氏菌对喹诺酮类药物的耐药性与耐药基因携带情况并分析其相关性,通过K-B药敏纸片和PCR方法分别检测24株貉源致病性肺炎克雷伯氏菌对喹诺酮类药物耐药性与耐药基因。结果表明:24株貉源致病性肺炎克雷伯氏菌呈现多重耐药性,对左氧氟沙星、恩诺沙星、环丙沙星、诺氟沙星耐药性为70.8%—79.2%,耐4种抗生素的菌株有16株,占分离菌株的66.7%;24株貉源致病性肺炎克雷伯氏菌的耐药基因gyrB、oqxA、parC、parE、oqxB、ompF检出率在70.8%以上 ...
张召兴 1 +1 more
doaj
ABSTRACT Background Chronic cases of canine otitis externa (OE) often develop infections with Pseudomonas aeruginosa (PA). Given the organism's high level of resistance, veterinary surgeons often turn to compounded solutions. Limited data describing the stability and potency of compounded ceftazidime (CAZ) solutions are available, which may affect ...
McKenna Snidow +6 more
wiley +1 more source
目的通过分析会阴侧切分娩产妇感染病原菌的分布和耐药性,为临床治疗和抗菌药物的使用提供参考。方法对2016年8月至2018年12月期间在攀枝花市妇幼保健院进行会阴侧切分娩发生感染的34例产妇的伤口分泌物进行细菌培养、鉴定及药敏试验。结果 34例发生感染的产妇侧切伤口分泌物中共检出49株病原菌,其中包括革兰阴性菌31株,占比63.27%;革兰阳性菌18株,占比36.73%;真菌0株,占比0.00%。主要革兰阴性菌对庆大霉素、克林霉素、氧氟沙星和多粘菌素的耐药性都较高,且耐药率都在50.00%以上 ...
张丽 +4 more
doaj

