Results 21 to 30 of about 1,280 (139)
Progress in epigenetic modification of ferroptosis involved in chronic obstructive pulmonary disease [PDF]
Ferroptosis is a special type of programmed cell death, which is different from autophagy, apoptosis and other modes of death, and characterized by mitochondrial shrinkage, membrane density increase and ridge reduction.
CAI Xiaoyu +3 more
core +1 more source
Potential role of SUMO-specific proteases 1 in ferroptosis [PDF]
Objective·To explore the potential role of SUMO-specific protease 1 (SENP1) in ferroptosis.Methods·The Cancer Genome Atlas (TCGA) database was used to analyze the correlation between the expression levels of SENP1 and the ferroptosis-related genes, acyl ...
BAI Meng +5 more
core +1 more source
The research on FBW7 gene enhances antitumor effect of paclitaxel on pancreatic cancer through GSDME-mediated pyroptosis [PDF]
, 2023 Background and purpose: Pancreatic cancer is a highly malignant disease. Most patients are in advanced stage upon diagnosis. Systemic chemotherapy is an important treatment method, but the chemotherapy drug resistance to tumors brings many problems to ...
JIA Yuming, YE Zeng, DENG Yanli, LI Shengchao, ZHANG Zhilei, WANG Chao, XU Xiaowu, QIN Yi, PENG Li
core +1 more source
Agrimoiin promotes NRF2-mediated ferroptosis of gastric cancer cells by inhibiting the PI3K-AKT pathway [PDF]
Objective To observe the inhibitory mechanism of agrimoiin on human gastric cancer cell line HGC-27 and MKN-45. Methods Gastric cancer HGC-27 and MKN-45 cells were divided into control group, different doses of agrimoniin groups, capecitabine (positive ...
CHI Wencheng +4 more
core +1 more source
Regulatory effect of 5'tRF-LysCTT on ferroptosis in mouse cardiomyocytes and its mechanism [PDF]
Objective To investigate the regulatory effect of tRNA-derived small RNA (tsRNA) on ferroptosis in mouse cardiomyocytes and its mechanism. Methods RT-qPCR was used to measure the relative expression level of 5'tRF-LysCTT in the heart, liver, spleen ...
ZHAO Yan, WANG Kai, CHENG Xueli, WANG Kun
core +1 more source
Community‐informed and codesigned research to understand the impacts of railways on wildlife
Conservation Biology, Volume 39, Issue 5, October 2025.Abstract Trains cause mortalities of several animal species, but the ecological impacts of railways are understudied. Most research on wildlife–train collisions has focused on large mammals, but understanding railway‐specific risks for underrepresented taxa, especially vulnerable species, is important for developing effective mitigation strategies ...
Kyle D. Vincent +5 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2023 目的 本研究利用机器学习探索IgA肾病(IgAN)铁死亡的潜在诊断标志物及其生物学过程，并研究其与IgAN免疫细胞浸润的关系。方法 从GEO数据库中下载来自IgAN患者和对照组的肾小球组织的微阵列数据集(GSE93798,GSE104948),通过FerrDb数据库获取全部铁死亡相关基因数据，获得IgAN组和对照组中有差异表达的铁死亡相关基因 ...
杨柏新 +4 more
doaj
The role of ferroptosis suppressor protein 1 in tumors [PDF]
Ferroptosis suppressor protein 1 （FSP1） is a key suppressor in the process of ferroptosis， which can prevent cell death and has important biological functions and potential value in clinical application.
LI Hantong, LI Yuefan, ZHOU Yan, WANG Lin
core +1 more source
Zhongguo shiyan zhenduanxue, 2022 目的 在胆管癌（CCA）中用铁死亡相关长链非编码RNA(lncRNA)建立有较好的预测能力的预后模型。方法 从TCGA数据集下载CCA的转录组RNA-seq数据和相应的临床数据。采用Pearson相关法筛选与铁死亡相关的差异表达的lncRNAs。单因素Cox回归分析用来筛选与预后相关的lncRNAs。通过多因素回归分析构建预后模型，采用受试者工作特征曲线（ROC）下面积和Kaplan-Meier曲线对模型进行评价。结果 筛选出3个铁死亡相关的差异表达lncRNAs:LINC01714 ...
张琳, 石张镇, 白元松
doaj
Characterization of hub genes associated with ferroptosis in diabetic nephropathy [PDF]
Objective To identify hub genes associated with ferroptosis in the progression of diabetic nephropathy （DN） through bioinformatics analysis， offering novel insights into DN treatment.
ZHAO Sheng, LI Wenchuan, DONG Lan, LIAN Rong, LI Yuejiao, HE Feng
core +1 more source