Results 151 to 160 of about 101,287 (245)

1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry. [PDF]

ACS Med Chem Lett, 2021
Aprile S, Riva B, Bhela IP, Cordero-Sanchez C, Avino G, Genazzani AA, Serafini M, Pirali T.   +7 more
europepmc   +1 more source

1,2,4-Oxadiazole Derivatives: Physicochemical Properties, Antileishmanial Potential, Docking and Molecular Dynamic Simulations of Leishmania infantum Target Proteins. [PDF]

Molecules
Barbosa DCS, Holanda VN, Lima EMA, Cavalcante MKA, Brelaz-de-Castro MCA, Chaves EJF, Rocha GB, Silva CJO, Oliveira RN, Figueiredo RCBQ.   +9 more
europepmc   +1 more source

Development of Diphenyl-1,2,4-Oxadiazole Analogues as Allosteric Modulators of the RXFP3 Receptor: Evaluation of Importance of the N-Substituted-2-Pyrrolidone Moiety in RLX-33. [PDF]

J Med Chem
Guan D, Chaminda Lakmal HH, Bender BN, Rahman MT, Gay EA, Barrus DG, Mosera AM, Kerr AT, Besheer J, Jin C.   +9 more
europepmc   +1 more source

Discovery of FO-4-15, a novel 1,2,4-oxadiazole derivative, ameliorates cognitive impairments in 3×Tg mice by activating the mGluR1/CaMKIIα pathway. [PDF]

Acta Pharmacol Sin
Luo ZH, Guo JS, Pang S, Dong W, Ma JX, Zhang L, Qi XL, Guan FF, Gao S, Gao X, Liu N, Pan S, Chen W, Zhang X, Zhang LF, Yang YJ.   +15 more
europepmc   +1 more source

Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-based derivatives as multitarget anti-Alzheimer agents. [PDF]

RSC Med Chem
Ayoup MS, Barakat MR, Abdel-Hamid H, Emam E, Al-Faiyz YS, Masoud AA, Ghareeb DA, Sonousi A, Kassab AE.   +8 more
europepmc   +1 more source

New Alpha9 nAChR Ligands Based on a 5-(Quinuclidin-3-ylmethyl)-1,2,4-oxadiazole Scaffold. [PDF]

ACS Chem Neurosci
Dallanoce C, Richter K, Stokes C, Papotto C, Andleeb H, Thakur GA, Kerr A, Grau V, Papke RL.   +8 more
europepmc   +1 more source

Novel late-stage radiosynthesis of 5-[18F]-trifluoromethyl-1,2,4-oxadiazole (TFMO) containing molecules for PET imaging. [PDF]

Sci Rep, 2021
Turkman N, Liu D, Pirola I.
europepmc   +1 more source

Correction: computational design, synthesis, and assessment of 3-(4-(4-(1,3,4-oxadiazol-2-yl)-1H-imidazol-2-yl)phenyl)-1,2,4-oxadiazole derivatives as effective epidermal growth factor receptor inhibitors: a prospective strategy for anticancer therapy. [PDF]

RSC Med Chem
Khedkar NR, Sindkhedkar M, Joseph A.
europepmc   +1 more source

1,2,4-Oxadiazoles: Synthesis and Applications

Revista Virtual de Química, 2012
Jucleiton José R. de Freitas, Edilma Elayne da Silva, Juliana L. L. F. Regueira, Suelâeny A. de Andrade, Phelipe Matheus M. Calvalcante, Ronaldo N. de Oliveira, João R. de Freitas Filho   +6 more
openaire   +1 more source

Synthesis and Bioactivity of 1,2,4-Oxadiazoles

Revista Virtual de Química, 2015
Felipe S. Cunha, Alcino P. de Aguiar
openaire   +1 more source