Results 91 to 100 of about 29,220 (210)

Ring Transformation of Oxazolo [3,2-b][1,2,4] Triazines [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1995
6-Methyl-2-phenyl-7H-Oxazolo [3,2-b] [1,2,4] triazine (1) undersent ting transformation on treatment with ammonia and primary amines to afford the corresponding imidazol [1,2-b][1,2,4] triazine (2).
Majid M. Heravi, Mehdi Bakavoli, Zohreh Sadjadi Hashemi   +2 more
doaj  

Novel 5-Substituted 2-(Aylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl)benzenesulfonamides: Synthesis, Molecular Structure, Anticancer Activity, Apoptosis-Inducing Activity and Metabolic Stability

Molecules, 2016
A series of novel 5-substituted 2-(arylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl) benzenesulfonamide derivatives 27–60 have been synthesized by the reaction of aminoguanidines with an appropriate phenylglyoxal hydrate in glacial acetic acid.
Beata Żołnowska, Jarosław Sławiński, Aneta Pogorzelska, Krzysztof Szafrański, Anna Kawiak, Grzegorz Stasiłojć, Mariusz Belka, Szymon Ulenberg, Tomasz Bączek, Jarosław Chojnacki   +9 more
doaj   +1 more source

Two mutually complementary synthetic approaches towards 3-substituted 3,4-disubstituted and 1-(2-pyridyl)-substituted isoquinolines

Chimica Techno Acta, 2018
Two mutually complementary synthetic approaches towards 3- and 3,4-disubstituted 1-(2-pyridyl) isoquinolines were studied. The aryne-based method was successfully used for the obtaining of the corresponding the 3-cyano-1-(2-pyridyl)isoquinolines in one ...
I. L. Nikonov, D. S. Kopchuk, A. F. Khasanov, A. P. Krinochkin, E. S. Starnovskaya, Ya. K. Shtaiz, M. I. Savchuk, O. S. Tanya, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin   +10 more
doaj   +1 more source

Isoxazolyl-Derived 1,4-Dihydroazolo[5,1-c][1,2,4]Triazines: Synthesis and Photochemical Properties. [PDF]

Molecules, 2023
Sadchikova EV, Safronov NE, Beliaev NA, Nenajdenko VG, Belskaya NP.   +4 more
europepmc   +1 more source

The activity of pyrazolo[4,3-e][1,2,4]triazine and pyrazolo[4,3-e]tetrazolo[1,5-b][1,2,4]triazine sulphonamide derivatives in monolayer and spheroid breast cancer cell cultures

Journal of Enzyme Inhibition and Medicinal Chemistry
In the last decade, an increasing interest in compounds containing pyrazolo[4,3-e][1,2,4]triazine moiety is observed. Therefore, the aim of the research was to synthesise a novel sulphonyl pyrazolo[4,3-e][1,2,4]triazines (2a, 2b) and pyrazolo[4,3-e ...
Anna Szymanowska, Dominika Radomska, Robert Czarnomysy, Mariusz Mojzych, Katarzyna Kotwica-Mojzych, Krzysztof Bielawski, Anna Bielawska   +6 more
doaj   +1 more source

A Facile Synthesis of Pyrido[2′,3′:3,4]pyrazolo[1,5-a]pyrimidine and Pyrido[2′,3′:3,4]pyrazolo[5,1-c][1,2,4]triazine Bearing a Thiophene Moiety

Journal of Chemistry, 2013
Pyridinone derivative 8 was synthesized and transformed into the respective chloropyridine 9, which was allowed to react with hydrazine hydrate to afford pyrazolo[3,4-b]pyridin-3-amine derivative 11.
Tilal Elsaman, Mohamed Fares, Hatem A. Abdel-Aziz, Mohamed I. Attia, Hazem A. Ghabbour, Kamal M. Dawood   +5 more
doaj   +1 more source

Triazines, Tetrazines, and Fused Ring Polyaza Systems

, 2012
The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for 1,2,3-triazines, 1,2,4-triazines, 1,3,5-triazines, tetrazines, and purines are reviewed.
Prokhorov, Anton M., Kozhevnikov, Dmitry N., Dmitry N. Kozhevnikov, Anton M. Prokhorov   +3 more
core   +1 more source

The features of nucleophilic substitution of the nitro group in 4-alkyl-6-nitro-1,2,4-triazolo[5,1-c][1,2,4]triazines

Chimica Techno Acta, 2017
The nucleophilic substitution of the nitro group of 4-alkyl-6-nitro-4,7-dihydro-1,2,4-triazolo[5,1-c][1,2,4]triazine-7-ones on the example of interactionwith morpholine was studied.
E. N. Ulomsky, D. N. Lyapustin, V. V. Fedotov, O. S. El'tsov, I. M. Sapozhnikova, D. N. Kozhevnikov, E. M. Mukhin   +6 more
doaj   +1 more source

Synthesis of 3-(Alkylamino)-, 3-(Alkoxy)-, 3-(Aryloxy)-, 3-(Alkylthio)-, and 3-(Arylthio)-1,2,4-triazines by Using a Unified Route with 3-(Methylsulfonyl)-1,2,4-triazine

, 2016
In our attempts to synthesize 3‐(alkylthio)‐ and 3‐(alkoxy)‐1,2,4‐triazines without substituents at the 5‐ or 6‐position, the synthesis of their anticipated precursor 3‐(methylsulfonyl)‐1,2,4 triazine was also optimized.
Gable, RW, Shi, DH, Harjani, JR, Baell, JB   +3 more
core   +1 more source

Crystal Structure Analysis of 4-Oxo, 4-hydroxy- and 4-alkyl-7-bromopyrazolo[5,1-c][1,2,4]triazines. [PDF]

J Chem Crystallogr, 2022
Ivanov SM, Koltun DS.
europepmc   +1 more source