Results 121 to 130 of about 976 (164)

Antimalarials. 3. 1,2,4-Triazines

Journal of Medicinal Chemistry, 1976
The syntheses of a number of substituted 1,2,4-triazines as potential antimalarials are described. The structural requirements for antimalarial activity are discussed with reference to the substituents of a phenyl group in the 6 position and amino groups at the 3 and 5 positions.
L C, March, G S, Bajwa, J, Lee, K, Wasti, M M, Joullíe   +4 more
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1,2,4‐Triazine N‐Oxides

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
D.N Kozhevnikov, V.L Rusinov, O.N Chupakhin   +2 more
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3-Amino-1,2,4-triazine

Acta Crystallographica Section C Crystal Structure Communications, 2002
In the crystal structure of 3-amino-1,2,4-triazine, C(3)H(4)N(4), the molecules form hydrogen-bonded chains that are almost parallel to the b axis (3.2 degrees), and which are inclined to the a and c axes by approximately 21 and approximately 69 degrees, respectively.
Genivaldo Julio, Perpétuo, Jan, Janczak
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ChemInform Abstract: 1,2,4‐TRIAZINES PART 10, DIMERIZATIONS OF 1,2,4‐TRIAZINES

Chemischer Informationsdienst, 1973
AbstractAus den 1,2,4‐Triazinen (I) mit freier 5‐Stellung erhält man in der angegebenen Weise bei der Behandlung mit Methylat oder mit Kaliumcyanid über anionische Zwischenstufen Dimere wie (II).
D. K. KRASS, T.‐K. CHEN, W. W. PAUDLER
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Synthesis and Anti-Inflammatory Evaluation of 3-Methylthio-1,2,4-Triazines, 3-Alkoxy-1,2,4-Triazines, and 3-Aryloxy-1,2,4-Triazines

Journal of Pharmaceutical Sciences, 1980
To develop nonacidic, nonsteroidal anti-inflammatory agents without GI complications, a series of asymmetric triazines was synthesized and evaluated for anti-inflammatory efficacy in the carrageenan-induced pedal edema assay. Toxicity was estimated by determination of approximate LD50 values in mice.
W P, Heilman, R D, Heilman, J A, Scozzie, R J, Wayner, J M, Gullo, Z S, Ariyan   +5 more
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Synthesis of 1,2,4-Triazines; XIII. Regioselective Synthesis of Trialkyl-1,2,4-triazines

HETEROCYCLES, 1992
Trialkyl-1,2,4-triazines (3) were prepared by heating α-oxoacylhydrazones (4) or N,N-dimethylaminomethylene hydrazones (19) with ammonium acetate at 100°C.
Hans Neunhoeffer, Tadashi Ohsumi
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Chemistry of 1,2,4‐triazines, XV. First metalation of 1,2,4‐triazine derivatives

Liebigs Annalen der Chemie, 1993
Abstract5‐Methoxy‐1,2,4‐triazines 2 were lithiated with lithium 2,2,6,6‐tetramethylpiperidide and the formed 6‐lithio‐5‐methoxy‐1,2,4‐triazines 4 trapped with aldehydes or iodine.
Nelly Plé, Alain Turck, Guy Quéguiner, Bernd Glassl, Hans Neunhoeffer   +4 more
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1,2,4-Triazine

2001
[290-38-0] C3H3N3 (MW 81.09) InChI = 1S/C3H3N3/c1-2-5-6-3-4-1/h1-3H InChIKey = FYADHXFMURLYQI-UHFFFAOYSA-N (electron-deficient heteroaromatic azadiene capable of participation in inverse electron demand Diels–Alder reactions with electron-rich dienophiles1) Alternate Names: as-triazine; α-triazine; isotriazine ...
Dale L. Boger, Minsheng Zhang
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Condensed 1,2,4‐Triazines, III

Archiv der Pharmazie, 1980
AbstractAlkylation of 3‐mercaptophenanthreno[9,10‐e]‐1,2,4‐triazine (1b) yielded the S‐alkyl derivatives 2 a‐d. Amination of 1a afforded the 3‐amino derivatives 3a‐h. Reaction of 1a with hydrazine hydrate gave 3‐hydrazinophenanthreno[9,10‐e]‐1,2,4‐triazine (4) which underwent cyclisation with nitrous, formic or acetic acids giving the phenanthreno[9,10‐
Vishnu Ji Ram, Hrishi Kesh Pandey
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Kondensierte Dihydro‐1,2,4‐triazine

Archiv der Pharmazie, 1987
AbstractHydrazone von α‐Aminoketonen mit cyclischem Aminanteil ergeben mit Quecksilber (II)‐EDTA eine Cyclodehydrierung zu entspr. kondensierten Dihydrotriazinen.
Hans Möhrle, Peter Schillings
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