Results 61 to 70 of about 37,751 (208)

15N-Labelling and structure determination of adamantylated azolo-azines in solution

open access: yesBeilstein Journal of Organic Chemistry, 2017
Determining the accurate chemical structures of synthesized compounds is essential for biomedical studies and computer-assisted drug design. The unequivocal determination of N-adamantylation or N-arylation site(s) in nitrogen-rich heterocycles ...
Sergey L. Deev   +10 more
doaj   +1 more source

Tailored Covalent Organic Framework Interphase Layer for High‐Performance Anode‐Free Lithium Metal Batteries

open access: yesAngewandte Chemie Novit, Volume 2, Issue 3, September 2026.
High‐performance anode‐free lithium (Li) metal batteries have been achieved using a covalent organic framework interphase layer, where its abundant nitrogen‐containing functional groups enable uniform Li+ adsorption and well‐defined porous architecture ensures dense Li metal deposition.
Zhaofeng Ouyang   +9 more
wiley   +1 more source

Triazines, Tetrazines, and Fused Ring Polyaza Systems

open access: yes, 2012
The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for 1,2,3-triazines, 1,2,4-triazines, 1,3,5-triazines, tetrazines, and purines are reviewed.
Prokhorov, Anton M.   +3 more
core   +1 more source

Enaminones as Building Blocks for the Synthesis of Substituted Pyrazoles with Antitumor and Antimicrobial Activities

open access: yesMolecules, 2011
Novel N-arylpyrazole-containing enaminones 2a,b were synthesized as key intermediates. Reactions of 2a,b with active methylene compounds in acetic acid in the presence of ammonium acetate afforded substituted pyridine derivatives 5a-d.
Sayed M. Riyadh
doaj   +1 more source

Broccoli Sprout Extract Restores Renal Lipid Metabolism in High‐Fat Diet‐Fed Mice Involving Modulation of AMPK/Nrf2 Signaling and the NLRP3 Inflammasome

open access: yesFood Science &Nutrition, Volume 14, Issue 9, September 2026.
High‐fat diet (HFD) induces renal lipid accumulation, AMPK suppression, oxidative stress, and NLRP3 inflammasome activation, leading to renal injury. Broccoli sprout extract (BSE) concurrently activates AMPK signaling (promoting fatty acid oxidation and inhibiting lipogenesis), enhances Nrf2‐mediated antioxidant defense, and suppresses NLRP3‐driven ...
Chunting Wu   +9 more
wiley   +1 more source

Synthesis of 3,4-dihydro-1,8-naphthyridin-2(1H)-ones via microwave-activated inverse electron-demand Diels–Alder reactions

open access: yesBeilstein Journal of Organic Chemistry, 2014
Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels–Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain.
Salah Fadel   +5 more
doaj   +1 more source

Nitrogen‐Rich 5,5′‐Azotetrazolates: A Broad Spectrum of Technologically Accessible Gas‐Generating Pyrotechnic Materials

open access: yesChemistryOpen, Volume 15, Issue 9, September 2026.
A series of ten 5,5′‐azotetrazolate salts with nitrogen‐rich bases is prepared and assessed as technologically accessible gas‐generating materials. Structural, safety, and ballistic evaluations reveal several compounds combining high bulk density, acceptable sensitivities, and favorable gas‐generation performance, highlighting the potential of ...
Adam Votýpka   +8 more
wiley   +1 more source

Dengue Virus Molecular Targets and Antiviral Drug Development: Advances, Challenges and Therapeutic Perspectives

open access: yesChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This narrative review analyzes DENV molecular targets, including structural proteins (C, prM/M, E), non‐structural components (NS1NS5), and host factors, alongside small‐molecule candidates in preclinical and clinical phases. Owing to high structural conservation, the NS2B‐NS3 protease and NS5 (RdRp/MTase) remain primary drug discovery focuses, while ...
Aryane Lucia da Silva Aguiar De Oliveira   +8 more
wiley   +1 more source

Dimethyl‐, Diethyl‐, and Propylene Carbonates: An Emerging Class of Green Solvents for Organic Synthesis

open access: yesThe Chemical Record, Volume 26, Issue 8, August 2026.
This review highlights recent advances in the use of organic carbonates, dimethyl carbonate (DMC), diethyl carbonate (DEC), and propylene carbonate (PC), as solvents in organic synthesis. Based on over seventy studies from the past 6 years, it shows their application in different organic reaction types, emphasizing their role in safer and more ...
Gabriela T. Quadros   +5 more
wiley   +1 more source

Discovery of Potent and Fast-Acting Antimalarial Bis-1,2,4-triazines

open access: yes, 2021
Novel 3,3′-disubstituted-5,5′-bi(1,2,4-triazine) compounds with potent in vitro activity against Plasmodium falciparum parasites were recently discovered.
Beveridge, Julia G   +37 more
core   +1 more source

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