Results 11 to 20 of about 2,851 (224)

Pharmacological aspects of application of 1,2,4-triazole-3-thiol furan derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016
Introduction. Nowadays 1,2,4-triazole-3-thiol furan derivatives have established themselves as a separate class of promising bioactive compounds. Presented substance is practically non-toxic and exhibits various kinds of pharmacological activity.
O. A. Bihdan, V. V. Parchenko, О. І. Panasenko, E. G. Knysh   +3 more
doaj   +4 more sources

Discussion of antimicrobial and antifungal activity of 4-amino-5-methyl-4H-1,2,4-triazole-3-thiol

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
Studying new biologically active substances nowadays become increasingly important. The current range of the pharmaceutical market requires constant updating of domestic products.
T. V. Kravchenko, O. I. Panasenko, Ye. G. Knysh   +2 more
doaj   +4 more sources

Photostability and Performance of Polystyrene Films Containing 1,2,4-Triazole-3-thiol Ring System Schiff Bases. [PDF]

Molecules, 2016
Series of 4-(4-substituted benzylideneamino)-5-(3,4,5-trimethoxyphenyl)-4H-1,2,4-triazole-3-thiols were synthesized and their structures were confirmed. The synthesized Schiff bases were used as photostabilizers for polystyrene against photodegradation.
Ali GQ, El-Hiti GA, Tomi IH, Haddad R, Al-Qaisi AJ, Yousif E.   +5 more
europepmc   +5 more sources

Synthesis of Some New 4,5-Substituted-4H-1,2,4-triazole-3-thiol Derivatives [PDF]

Molecules, 2004
In this study appropriate hydrazide compounds, furan-2-carboxylic acidhydrazide (1) and phenylacetic acid hydrazide (2) were converted into 1,4-substitutedthiosemicarbazides 4a-e and 5a-e and 4-amino-5-(furan-2-yl or benzyl)-4H-1,2,4-triazole-3-thiols 7 and 10.
A. Demirdağ, A. Cansız, M. Koparır   +2 more
openaire   +3 more sources

Synthesis and antimicrobial activity of s-substituted derivatives of 1,2,4-triazol-3-thiol

ScienceRise: Pharmaceutical Science, 2021
The aim of the work. 1,2,4-triazole derivatives possess a wide range of pharmacological activity, so they are used for the development of drugs and active pharmaceutical ingredients. Due to the reactivity of 1,2,4-triazoles there are many options for their further structural modification on different reaction centers. Therefore, the aim of the work was
Yevhen Karpun, Nataliia Polishchuk
openaire   +3 more sources

Synthesis, characterization and biological activity of Hg(II), Fe(III) complexes with 1,3,4-oxadiazole, 1,2,4-triazole derivatives from L-methionine

Journal of Saudi Chemical Society, 2020
Four novel heterocyclic1,3,4-oxadiazole, 1,2,4-triazole derivatives, namely: 5-[1-amino-3-(methylsulfanyl)propyl]-1,3,4-oxadiazole-2(3H)-thione (4), 4-amino-5-[1-amino-3-(methylsulfanyl)propyl]-4H-1,2,4-triazole-3-thiol (5), 1-amino-3-[1-amino-3 ...
Khaled Briki, Adil Ali Othman, Mouna Souad Abbassi, Mokhtar Boualem Lahrech   +3 more
doaj   +1 more source

Synthesis and Characterization of the Triazole Derived from Thiosemicarbazide, 4-Amino-5-Phenyl-4H-1,2,4- Triazole-3-Thiol and Their Copper(II) and Nickel(II) Complexes [PDF]

Engineering and Technology Journal, 2013
Triazole N-(3-mercapto-5-phenyl-4H-1,2,4-triazol-4-yl)hydrazinecarbothioamide prepared in good yield via the condensation of 4-amino-5-phenyl-4H-1,2,4-triazole-3-thiol and thiosemicarbazide.
Hamdan Abood Aday
doaj   +1 more source

Antimicrobial and antifungal activity of new fluorophenyl-containing 1,2,4-triazoles

Фармацевтичний журнал, 2021
The achievements of the world organic chemistry are most clearly represented by scientific publications that prove the promising nature of heterocyclic substances.
O. A. Bihdan
doaj   +1 more source

Synthesis, antimicrobial and antifungal activity of 3-(2-bromophenyl)-5-(alkylthio)-4-phenyl-4H-1,2,4-triazoles

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
To select a molecule that could become a promising pharmacological agent, chemists use already-known heterocyclic bases by adding pharmacologically active groups. One such heterocyclic system is 1,2,4-triazole base, on the basis of which a huge number of
A. A. Safonov, O. I. Panasenko
doaj   +1 more source

Synthesis and properties of some pyrazole derivatives of 1,2,4-triazole-3-thiol

Current issues in pharmacy and medicine: science and practice, 2020
Nitrogen-containing heterocyclic compounds play an important role in the modern pharmaceutical industry. This is due to their significant biological potential. 1,2,4-Triazole and pyrazole are known pharmacophores that are responsible for the formation of a wide range of activities.
Hotsulia, A. S., Kulish, S. M.
openaire   +4 more sources