Results 11 to 20 of about 26,240 (223)
Synthesis of some New 1,2,4-Triazole derivatives [PDF]
مجلة جامعة الانبار للعلوم الصرفة, 2013 In the present work, compound 3-arylidene amino-5-methyl-1,2,4-triazole (IIIa-c), required as starting material obtained in one-pot reaction by condensing 5-methyl-3-amino-1,2,4-triazole with different aromatic aldehydes.
Ibtehal Kahtan Abdullah
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Synthesis and Antimicrobial Activity of 1,2,4-Triazoles [PDF]
E-Journal of Chemistry, 2005 Several 3-(4'-nitrophenyl)-4-(4"-chloro benzamido)-5-substituted phenyl)-4H-1,2,4-triazole (3a-3e) and 3-(4'-nitrophenyl)-4-(4"-methyl benzenesulphonamido)-5-substituted phenyl)-4H-1,2,4-triazole (4a-4e) have been synthesised.
R. U. Roy, A. R. R. Desai, K. R. Desai
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Synthesis and spectral characterization of 1,2,4-triazole derivatives [PDF]
AIP Conference Proceedings, 2022 The authors G. Sravya and N. Bakkthavatchala Reddy are thankful to Ural Federal University, Yekaterinburg, Russia for financial assistance and thankful to Prof. A. Padmaja for providing necessary lab facility to carry out this research work.
Reddy, N. B. +5 more
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1,2,4-Triazoles as Important Antibacterial Agents [PDF]
Pharmaceuticals, 2021 The global spread of drug resistance in bacteria requires new potent and safe antimicrobial agents. Compounds containing the 1,2,4-triazole ring in their structure are characterised by multidirectional biological activity. A large volume of research on triazole and their derivatives has been carried out, proving significant antibacterial activity of ...
Małgorzata Strzelecka, Piotr Świątek
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Synthesis methods of 1,2,3-/1,2,4-triazoles: A review
Frontiers in Chemistry, 2022 Triazole, comprising three nitrogen atoms and two carbon atoms, is divided into two isomers 1,2,3-triazole and 1,2,4-triazole. Compounds containing a triazole are one of the significant heterocycles that exhibit broad biological activities, such as antimicrobial, analgesic, anti-inflammatory, anticonvulsant, antineoplastic, antimalarial, antiviral ...
Jinlian Dai +3 more
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3-Nitro-1H-1,2,4-triazole [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 تحتوي الوحدة غير المتماثلة لمركب العنوان، C(2)H(2)N(4)O(2)، على جزيئتين مستقلتين بلوريًا تكون فيهما حلقات التريازول مستوية بشكل أساسي، مع انحرافات قصوى قدرها 0.003 (1) Å في كلا الجزيئين. الزاوية الثنائية السطوح بين حلقتي 1H -1،2،4 - triazole هي 56.58 (5)درجة.
Madhukar Hemamalini, Hoong‐Kun Fun
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Novel protein contact points among TP53 and minichromosome maintenance complex proteins 2, 3, and 5
Cancer Medicine, Volume 11, Issue 24, Page 4989-5000, December 2022., 2022 Using a next‐generation sequencing‐based protein‐protein interaction method, we identified interactions among MCM2, MCM3, and MCM5. While many of the interacting regions we detected overlap with existing structural data of the complex, we also recovered novel domains with higher resolution.
Stephanie Schaefer‐Ramadan +3 more
wiley +1 more source
Preparation and antitumor effects of 4-amino-1,2,4-triazole Schiff base derivative
Journal of International Medical Research, 2020 Objectives The purpose of this paper was to synthesize 4-amino-1,2,4-triazole Schiff base derivative and to evaluate its antitumor activity. Methods 2,4,6-Tris (4-formylphenoxy)-1,3,5-triazine was synthesized by nucleophilic substitution with reaction of
Guo-wei Jiang +5 more
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Theoretical Study of Tautomeric Conformations for 1,2,4-Triazole Derivatives
Orbital: The Electronic Journal of Chemistry, 2021 We have performing theoretical calculations of the 1,2,4-triazole derivatives using DFT B3LYP method to study the tautomeric conformations of 1,2,4-triazole-3-thiol (TL 2A and TL 2C) and 1,2,4-triazole-3-thione (TL 2B) derivatives.
Radia Mahboub
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Synthesis and alkylation of 5-aryl-1,2-dihydro-3H-1,2,4-triazole-3-thiones
Журнал органічної та фармацевтичної хімії, 2021 5-R-1,2,4-triazole-3-thiones and their derivatives are easy to obtain; they have low toxicity and a broad spectrum of the biological activity. It makes this class of heterocyclic compounds promising for creating potential drugs. Aim.
Dmytro V. Dovbnya +2 more
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