Effect of different vitamin D3 metabolites on intestinal calcium homeostasis-related gene expression in broiler chickens [PDF]
The purpose of this study was to investigate the effects of vitamin D3 metabolites 1α-hydroxycholecalciferol (1α(OH)D3), 25-hydroxycholecalciferol (25(OH)2D3), and 1,25-dihydroxycholecalciferol (1,25(OH)2D3) on growth performance, bone quality, and ...
Felix Shih-Hsiang Hsiao +4 more
doaj +3 more sources
- A 7 × 2 factorial experiment was designed to test the effects of calcium (Ca) to non-phytate phosphorus (NPP) ratio (1.14, 1.43, 1.71, 2.00, 2.29, 2.57, and 2.86) and different sources of vitamin D (1α-hydroxycholecalciferol (1α-OH-D3) and 25 ...
Jincheng Han +7 more
doaj +2 more sources
The Effect of Alpha-Hydroxycholecalciferol and Phytase on the Performance, Carcass Characteristics, Blood Factors, and Expression of Vdr and Cabp-D28k Genes in Broiler Chickens [PDF]
We evaluated the effect of alpha-hydroxycholecalciferol (1α-OH-D3) and phytase supplementation on the performance, carcass characteristics, blood factors, and the expression of vitamin D receptors (VDR) and Calbindin 28k (CaBP-D28k) genes in broiler ...
A Habibi, N Eila, M Paryani, A Zarei
doaj +3 more sources
25-Hydroxy- and 1α,25-Dihydroxycholecalciferol Have Greater Potencies than 25-Hydroxy- and 1α,25-Dihydroxyergocalciferol in Modulating Cultured Human and Mouse Osteoblast Activities. [PDF]
Despite differences in the phamacokinetics of 25-hydroxycholecalciferol (25(OH)D3) and 25-hydroxyergocalciferol (25(OH)D2) in man, the effects of these and their 1α-hydroxylated forms (1,25(OH)2D3 and 1,25(OH)2D2) on cellular activity of vitamin D ...
Allahdad Zarei +4 more
doaj +3 more sources
Safety and efficacy of a feed additive consisting of 25-hydroxycholecalciferol monohydrate produced with <i>Saccharomyces cerevisiae</i>CBS 146008 for all ruminants (DSM Nutritional Products Sp. z.o.o.). [PDF]
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of 25‐hydroxycholecalciferol monohydrate produced with Saccharomyces cerevisiae CBS 146008 as a nutritional feed additive for all ruminants.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +25 more
europepmc +2 more sources
Safety and efficacy of a feed additive consisting of 25-hydroxycholecalciferol (produced by <i>Pseudonocardia autotrophica</i>DSM 32858) for all pigs, all poultry for fattening and ornamental birds and other poultry species (Huvepharma NV). [PDF]
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of 25‐hydroxycholecalciferol (produced by Pseudonocardia autotrophica DSM 32858) for all pigs, all poultry for fattening and ornamental birds and other poultry species.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +32 more
europepmc +2 more sources
Impact of Polymorphisms in Genes Related to Vitamin D Metabolism on Serum Response to Supplementation in Adults and Elderly: A Systematic Review and Meta-Analysis Protocol. [PDF]
ABSTRACT Background and Aims Vitamin D deficiency is a major public health issue, with varying individual responses to supplementation. Genetic factors, especially single‐nucleotide polymorphisms (SNPs) in Vitamin D metabolism genes, likely play a key role.
Franco-Gedda LP +4 more
europepmc +2 more sources
The Hidden Burden of Water-Binding Additives in Meat Products: Biochemical, Clinical, and Psychosocial Implications. [PDF]
Graphical abstract illustrating how brining technology introduces water‐binding additives into processed meat. Their cumulative exposure may promote oxidative stress, inflammation, dysbiosis, and endothelial dysfunction, contributing to cardiovascular disease, chronic kidney disease, colorectal cancer, and metabolic burden, while highlighting the need ...
Kamyshnyi O +9 more
europepmc +2 more sources
Supraphysiological 25-Hydroxyvitamin D<sub>3</sub> and Calcipotriol Induce Reactive Oxygen Species, Mitochondrial Dysfunction and Apoptosis in HeLa Cervical Cancer Cells. [PDF]
Supraphysiological 25(OH)D3 and calcipotriol induced ROS accumulation or redox disturbance, increased mitochondrial membrane depolarization, reduced antioxidant enzyme activity, and caused apoptotic cell death in HeLa cells. ABSTRACT Cervical cancer remains a major global health challenge, necessitating continued advances in therapeutic strategies ...
Chan HCC +5 more
europepmc +2 more sources
ABSTRACT In a 36‐month randomized controlled trial examining the effect of high‐dose vitamin D3 on radial and tibial total bone mineral density (TtBMD), measured by high‐resolution peripheral quantitative tomography (HR‐pQCT), participants (311 healthy males and females aged 55–70 years with dual‐energy X‐ray absorptiometry T‐scores > −2.5 without ...
Lauren A. Burt +6 more
wiley +1 more source

